Ruben Esse Email & Phone Number

London Area, United Kingdom

• Using in-house and publicly available multidimensional omics data, spearhead high-depth understanding of gene delivery and stem cell maintenance and differentiation processes.
• Establish novel computational pipelines for interrogation of multimodal omics data.
• Contribute to team upskilling in basic wrangling and plotting data in R.
• Champion team welfare and lab operational improvements by chairing monthly staff meetings, fostering a collaborative and productive environment.

London, England, United Kingdom

• Provided in-depth subject matter expertise in next-generation sequencing (NGS) approaches for biomarker discovery, supporting innovation in AAV manufacturing and iPSC product development processes.
• Working in a matrix environment, contributed to the effective design and planning of laboratory work, ensuring scientific rigor.
• Authored experimental plans, protocols, and reports.
• Mentored junior staff in molecular biology techniques, fostering both technical expertise and career development.

London, England, United Kingdom

• Conducted research on gene regulatory mechanisms in adipose tissue development, managing experimental design and execution.
• Actively mentored junior colleagues, providing one-on-one guidance in experimental planning, execution, and data interpretation.

Boston, Massachusetts, United States

• Led the discovery of a novel role for a histone methyltransferase in enhancer control, presenting findings at international scientific meetings.
• Developed and managed the deployment of a custom bioinformatics application for ChIP-seq data analysis, bridging the gap between wet-lab research and complex computational analysis.
• Mentored new lab members in experimental techniques and bioinformatics workflows.

New York, New York, United States

• Pioneered research establishing the connection between methyltransferase DOT1L and transcriptional activation by an oncogene.
• Guided junior researchers in lab procedures and complex data analysis, fostering a culture of knowledge-sharing and continuous learning.

Lisbon, Portugal

• Uncovered the role of protein methylation disturbance in homocysteine-related diseases.

Lisbon, Portugal

• Contributed laboratory work to diagnose inborn errors of metabolism using patient specimens.

Doctor Of Philosophy - Phd, Biochemistry, Summa Cum Laude

Thesis: "Disturbed protein arginine methylation in hyperhomocysteinemia"

Master Of Science - Ms, Biological Engineering, 18/20

Final thesis: "Study of the physiological and transcriptional responses of Saccharomyces cerevisiae to hop iso-α-acids"

Bachelor Of Science - Bs, Biotechnology, 16/20