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• PhD (Biomedical Science) with postdoctoral research experience in the preclinical development of antibody/polymer therapeutics for cancer treatment.• Track record of scientific accomplishments - Filed 6 patent applications, and published 8 first-authored research articles as well as more than 30 co-author papers in top-tier journals. • Experience in the development and evaluation of antibody-based therapeutics (ADCs, Ab-oligos, and Ab-peptide) and other nanomedicines - Developed antibody/polymer therapeutics for targeting cancer treatment. Characterized the pharmacokinetics, biodistribution, metabolism, targeting effect, and therapeutic efficacy in various preclinical animal models.• Extensive experience and knowledge in pharmaceutics/pharmaceutical chemistry, biomedical science (oncology, biochemistry, molecular and cellular biology), preclinical animal models, and biomedical imaging (PET, SPECT, CT, fluorescence, bioluminescence, FRET).• Leadership and project management: - Successfully managed multiple projects, mentored students, and wrote the reports. Leveraged experts in problem solving.• Work in a multidisciplinary drug-development team for medicinal translation. .
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Senior Scientist IiProteologix Inc Apr 2024 - Present -
Senior Scientist IProteologix Inc Apr 2023 - Apr 2024 -
Scientist IiProteologix Inc Aug 2021 - Apr 2023 -
Senior Associate ScientistAmgen Jan 2019 - Aug 2021Thousand Oaks, Ca, Us -
Senior ScientistExcel Biopharm Feb 2018 - Jan 2019Develop and evaluate large panel of engineered antibodies or recombinant proteins for multiple projects.
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Contractor Associate ScientistGenentech Feb 2016 - Sep 2016South San Francisco, California, UsThe job focuses on investigating the pharmacokinetics, biodistribution, and PKPD relationships of novel antibody-based therapeutics in preclinical models to identify lead candidates for further development, and for bridging preclinical PKPD information to patients. -
ScientistTheratarget, Inc. Oct 2015 - Feb 2016Salt Lake City, Utah, UsThe work mainly focuses on the preclinical evaluation of antibody/copolymer-drug conjugates in vitro/in vivo for cancer treatment. Establishes cross-functional collaborations among institution, hospital and industry for clinical translation. -
Postdoctoral FellowUniversity Of Utah Nov 2011 - Feb 2016Salt Lake City, Utah, UsCurrent research focuses on the development of targeting drug delivery systems, including antibody conjugates (i.e., antibody-drugs (ADCs), antibody-peptide, antibody-oligos) and polymeric conjugates for the treatment of hematological malignancy and ovarian cancer. During this period, I had 1 patent application and 5 first-author research publications in top-tier journals, including PNAS, Advanced Healcare Materials, Theranostics, and Journal of Controlled Release. -
Graduate Research AssistantMd Anderson Cancer Center Sep 2006 - Nov 2011Houston, Tx, UsThe research included the preclinical development of nano-scale drug formulations for cancer treatment, especially on the antibody or peptide-functionalized targeting therapeutics. In addition, I could conduct a variety of animal models and biological techs during development. In my 5-year Ph.D. training, I had more than 25 co-authored paper published and one patent filed. -
Graduate Research AssistantZhejiang University Sep 2003 - Jul 2006杭州Hangzhou, 浙江Zhejiang, CnThe work mainly focused on the isolation and purification of bioactive compounds from traditional medicine.
Rui Zhang Skills
Rui Zhang Education Details
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The University Of Texas M.D. Anderson Cancer CenterBiomedical Sciences -
Zhejiang UniversityBiochemistry And Molecular Biology -
Zhejiang UniversityBiotechnology
Frequently Asked Questions about Rui Zhang
What company does Rui Zhang work for?
Rui Zhang works for Proteologix Inc
What is Rui Zhang's role at the current company?
Rui Zhang's current role is Senior Scientist at Proteologix.
What is Rui Zhang's email address?
Rui Zhang's email address is zh****@****ail.com
What schools did Rui Zhang attend?
Rui Zhang attended The University Of Texas M.d. Anderson Cancer Center, Zhejiang University, Zhejiang University.
What skills is Rui Zhang known for?
Rui Zhang has skills like Antibodies, Oncology, Pharmaceutics, Molecular Imaging, Preclinical Animal Studies, Molecular And Cellular Biology, Radiochemistry.
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