Ruth Bauer, M.S. Ascp(Mb) Email and Phone Number
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Highly skilled Senior Scientist with 20+ years of experience in molecular biology, assay development, and diagnostic technologies. Proven track record of evaluating emergent technologies and integrating 5 technologies into new devices, driving innovation in sample preparation, detection and chemistry stabilization.Leading with innovation, the fusion of my expertise in point-of-care (POC) assay development and dedication to medical diagnostics drives our advancements in ultrafast molecular testing. Our team's collaborative efforts have led to significant milestones for FDA submissions, reflecting a shared commitment to operational excellence and quality healthcare solutions.With a hands-on approach, I have formulated advanced PCR chemistries that enhance both assay reliability and speed, underpinning our mission to revolutionize patient care. My guidance in mentoring a dynamic team aligns with our company's strategic vision, ensuring that we continue to deliver groundbreaking results in the healthcare technology landscape.RESEARCH & DEVELOPMENT, ASSAY DEVELOPMENT, MOLECULAR DIAGNOSTICSAn analytical problem-solver with a keen eye for detail and a proven capacity to implement unique solutions to complex problems. Thrives in fast-paced and diverse environments that champion change and the use of cutting-edge technology.Self-motivated, creative, critical-thinking person highly regarded for creating complex molecular diagnostic assays, performing in-depth testing, and evaluating results to determine success of developed products within the Point of Care Molecular Diagnostics IVD field.Accountable, detail-oriented, hands-on scientist who fosters collaborative environments while inspiring high-performing, driven teams to deliver results that achieve technical success and personal growth. Leverages strong written and verbal communication skills to cultivate lasting relationships with members at all levels of an organization.
Vedabio
View- Website:
- vedabio.com
- Employees:
- 25
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VedabioUnited States
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Senior Scientist R&D Molecular Assay DevelopmentSekisui Diagnostics, Llc Apr 2019 - Jul 2024Burlington, Ma, UsLed the research and evaluation of 12+ companies with emergent technologies, integrating 5 technologies into a new device and new IP, driving innovation and expansion of the company's portfolio.Researched and tested 100+ combinations of excipients for assay lyophilization and rehydration leveraging deep knowledge of molecular biology, chemistry formulation and analysis.Prepared highly organized reports, implemented an internal tracking system for planning, execution and analysis and recording of experimentation. Presented as SME to international and domestic teams.Formulated PCR master mix using a multipronged screening for 30 enhancers and 20 enzymes, resulting in flexible, ultra-rapid PCR (<15 minutes) chemistry. -
Lead Scientist, R&D Molecular BiologyDna Electronics May 2018 - Nov 2018London, Gb✤ Supervised and mentored two high-performing research teams consisting of six direct reports as they collaborated on several large projects while managing the clinical development and feasibility testing of the medical device product. ✤ Utilized LiDiaTM system to screen and detect a panel of over 30 blood pathogens and antimicrobial resistance markers (AMR).✤ Formulated and allocated annual budgets, identifying essential personnel, CAPEX and non-CAPEX equipment, and service contracts needed for the department. ✤ Shared testing results with all team members and gathered findings into comprehensive reports to support all design process decisions made by executive management.✤ Negotiated and finalized terms of the contract that enabled the continued delivery of lyophilization materials companywide. ✤ Motivated and inspired cross-functional teams comprised of manufacturing, quality, product integration, and R&D members to attain the successful integration of workflow into a developed automated medical device, thus boosting overall efficiency over 100%. ✤ Partnered with executive management, business development, and R&D teams to assess project needs, determine scientific direction, and ensure milestone achievement. -
Senior Scientist I, Group LeaderDna Electronics May 2015 - Apr 2018London, Gb✤ Created and implemented a multiplexed model ‘6-plex’ qPCR assay tool that promptly assessed pH-PCR chemistry and overall performance of the pathogen capture system, while increasing process productivity.✤ Ensured compliance with all CDC requirements, applied approved permits to all purchases and maintained inventory for the blood pathogen bank containing hundreds of research microorganisms (level BSL-1/2). ✤ Applied for USDA plant pathogen permit for use as an internal control on a highly multiplexed molecular platform.✤ Devised and oversaw molecular migration procedures to QA/QC team for implementation including PCR swab tests and DNA plasmid preparation. ✤ Analyzed 20 molecular assays, a ’20-plex’, to identify and promptly resolve such issues as human DNA interference reduction using nuclease, qPCR optimization, DNA isolation and end to end performance. ✤ Calculated mass balance of process to determine total loss of sample at each step which resulted in an 50-90% improvement in overall sample yield. ✤ Evaluated 5 DNA isolation methodologies for assay compatibility and analyzed data to make critical recommendations for the commercialization of the final product.✤ Spearheaded efforts to gain additional lab space and three Core Lab personnel, supervising the newly formed laboratory and earning a 10-fold throughput increase across all technical teams.
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Scientist IiDna Electronics May 2012 - May 2015London, Gb✤ Oversaw all aspects of molecular assay development, including Taqman® probe-based and nested PCR, to target blood pathogens. ✤ Validated an in-house fungal multiplex ‘5-plex’ qPCR assay for use with Candida species targeted capture system. ✤ Collaborated with 20 team members over three years on $21.5M BARDA government contract to develop an innovative product that enabled Bacillus anthracis to be detected directly from blood. ✤ Leveraged knowledge of molecular DNA isolation to create six ‘DNAfree’ reagents and consumables for efficient pathogen DNA extraction. ✤ Submitted patent idea on the removal of DNA from the chaotropic reagent used in the extraction process.
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Senior Molecular Biology TechnologistExagen Diagnostics Jun 2011 - Mar 2012Vista, California, Us✤ Confirmed Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS) lab developed gene expression real-time PCR assays for CLIA lab. ✤ Isolated RNA using automated Qiagen QiaCube, RT-PCR, and LDT above on ABI 7300 real-time PCR instrument. ✤ Performed 100+/month clinical tests with 3 PCR assays using automated qPCR plate setup instrument (Eppendorf EpMotion 5070) and Real-Time PCR instruments (Applied Biosystems 7300, 7500). -
Molecular Technologist IiiTricore Reference Laboratories Jul 2008 - Jun 2011Albuquerque, Nm, Us✤ Conducted 500+/month clinical patient samples on multiple platforms and instruments to screen for genetic testing or acquired mutations in Molecular Diagnostics department. ✤ Provided ongoing assistance to two senior scientists as the lab introduced two additional esoteric testing validations for colorectal tumors and blood clotting polymorphism detection. ✤ Participated in annual CAP and CLIA accreditation and earned the Presidential Award for H1N1 support to virology during 2009 outbreak. ✤ Facilitated molecular esoteric testing including: BCR-ABL, PML-RARA, Factor II/V, IVGH, JAK2, CTFR, MGMT. ✤ Worked with 5 medical directors to analyze data and obtain results that delivered the best-care to clinical patients. -
Molecular TechnologistExagen Diagnostics, Inc. Oct 2005 - Jul 2008Vista, California, Us✤ Contributed to the research and development of two FDA submitted studies on breast cancer prognostic kit. ✤ Specialized in transferring technology to the manufacturing department and optimizing molecular assays. ✤ Participated in the creation of assays and diagnostics tests via fluorescent in-situ hybridization (FISH) and quantitative PCR techniques, including estrogen receptor negative breast cancer and Hepatitis C virus inflammatory response. ✤ Managed laboratory staffs of five or more scientists during projects that lasted for one month, per the request of executive management. ✤ Handled, organized, tracked, and inventoried large sample database and specimens upon receipt for use with various studies.
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Graduate Research AssistantUt Southwestern Medical Center Oct 2002 - Jul 2005Dallas, Texas, Us✤ Studied cell division and developed a new protocol to view larval fly brain cell development using FISH techniques.✤ Ran 50+ experiments on centrosomal protein Centrosomin (Cnn) to test for the biological functions of in vitro purified proteins. ✤ Researched chromosome segregation in Cnn mutants genetically and by FISH procedures. -
Research Technician Ii (Laboratory Of Dennis Mckearin, Ph.D)Ut Southwestern Medical Center Oct 2001 - Jul 2002Dallas, Texas, Us Garnered basic laboratory skills while performing entry-level fruit fly laboratory support work.
Ruth Bauer, M.S. Ascp(Mb) Skills
Ruth Bauer, M.S. Ascp(Mb) Education Details
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Ut Southwestern Medical CenterGenetics And Development -
The University Of New MexicoGeneral
Frequently Asked Questions about Ruth Bauer, M.S. Ascp(Mb)
What company does Ruth Bauer, M.S. Ascp(Mb) work for?
Ruth Bauer, M.S. Ascp(Mb) works for Vedabio
What is Ruth Bauer, M.S. Ascp(Mb)'s role at the current company?
Ruth Bauer, M.S. Ascp(Mb)'s current role is Senior Scientist/Lead Scientist R&D Molecular Assay Development leading innovative molecular solutions.
What is Ruth Bauer, M.S. Ascp(Mb)'s email address?
Ruth Bauer, M.S. Ascp(Mb)'s email address is ru****@****ail.com
What is Ruth Bauer, M.S. Ascp(Mb)'s direct phone number?
Ruth Bauer, M.S. Ascp(Mb)'s direct phone number is +181493*****
What schools did Ruth Bauer, M.S. Ascp(Mb) attend?
Ruth Bauer, M.S. Ascp(Mb) attended Ut Southwestern Medical Center, The University Of New Mexico.
What skills is Ruth Bauer, M.S. Ascp(Mb) known for?
Ruth Bauer, M.S. Ascp(Mb) has skills like Molecular Biology, Qpcr, Biotechnology, Laboratory, Fda, Clinical Research, Sequencing, Genetics, Pcr, Dna Extraction, Laboratory Skills, Life Sciences.
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