Ryan Gruber

Ryan Gruber Email and Phone Number

Associate Director, Precision Medicine Oncology Biomarker and Diagnostic Operations @ Johnson & Johnson Innovative Medicine
United States
Ryan Gruber's Location
Abington, Pennsylvania, United States, United States
Ryan Gruber's Contact Details

Ryan Gruber work email

Ryan Gruber personal email

About Ryan Gruber

Ryan Gruber is a Associate Director, Precision Medicine Oncology Biomarker and Diagnostic Operations at Johnson & Johnson Innovative Medicine. He possess expertise in drug discovery, biotechnology, in vivo, biochemistry, pharmacology and 7 more skills.

Ryan Gruber's Current Company Details
Johnson & Johnson Innovative Medicine

Johnson & Johnson Innovative Medicine

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Associate Director, Precision Medicine Oncology Biomarker and Diagnostic Operations
United States
Website:
jnj.com
Employees:
100890
Ryan Gruber Work Experience Details
  • Johnson & Johnson Innovative Medicine
    Associate Director, Precision Medicine Oncology Biomarker And Diagnostic Operations
    Johnson & Johnson Innovative Medicine
    United States
  • The Janssen Pharmaceutical Companies Of Johnson & Johnson
    Associate Director, Oncology Biomarker & Diagnostic Operations
    The Janssen Pharmaceutical Companies Of Johnson & Johnson May 2023 - Present
  • The Janssen Pharmaceutical Companies Of Johnson & Johnson
    Program Leader, Biomarker & Diagnostic Operations Oncology Translational Research
    The Janssen Pharmaceutical Companies Of Johnson & Johnson Mar 2021 - May 2023
  • Ecog-Acrin Cancer Research Group
    Director Of Translational Sciences, Oncology Biomarkers
    Ecog-Acrin Cancer Research Group Jul 2017 - Mar 2021
    Greater Philadelphia Area
    ● Director of the Translational Science Team, lead 6 direct reports located in Boston, MA.● Lead and managed the Translational Science Team, including overall biomarker clinical operations, infrastructure, communications, and planning and execution of activities for clinical trial development and correlative cancer research● Set priorities, timelines, and drove the overall deliverables for the Translational Science Team. Served as bridge between clinical development, operations, stats, labs, sites, CROs, vendors, and the specimen biorepository.● Oversaw and interacted with the ECOG-ACRIN biospecimen biorepository located at MD Anderson in Houston, TX. ● Performed biomarker research and presented at bi-annual conferences and meetings. Tracked biomarker research in trials. ● Developed protocols across multiple cancer disease areas, provided scientific input on biomarker strategy● Created, managed, and reviewed budgets, contracts, SOPs, and reports.● Interacted regularly with the National Cancer Institute (NCI), and other government, industry, and academic institutions. ● Lead and developed appropriate informatics platforms, including NCTN Navigator and LIMS for the National Cancer Institute.● Participated in Group Banking Subcommittees, and manages biospecimen banking activities, including consolidation efforts● Participated in working group and review committee meetings, and provided scientific and operational guidance.● Authored and submits various grants (U10, U24, BIQSFP) and progress reports● Participated in publication activities● Traveled to the bi-annual Group Meeting, and other scientific conferences as an ECOG-ACRIN representative.
  • Innovative Programming Associates
    Chief Scientific Officer
    Innovative Programming Associates Sep 2013 - Jun 2017
    ● Performed research in the field of oncology, including model development and methodology, data acquisition, meta-analysis, and discovery & development efforts related to cancer research and therapeutics. ● Oversaw scientific aspects of a small software programming company as lead scientist. ● Organized and presented capabilities of LABCAT software; a propriety data acquisition, analysis, and reporting software suite for in-life oncology research, necropsy, toxicology, pathology, pharmacology, and basic research. ● Interacted with a team of programmers to develop acquisition modules and macros for scientific research. ● Communicated with current and prospective clients, including training and troubleshooting. ● Tested and troubleshooted medical devices for data acquisition.
  • Gsk
    Program Manager - Biothreat Infectious Diseases
    Gsk May 2014 - Nov 2016
    Collegeville, Pa
    ● Member of the GSK Antibacterial Biothreat team focusing on discovery and development of therapeutics to treat multiple drug-resistant bacterial infections, including anthrax, plague, spotted fever, and other fatal diseases contributed to bioterrorism.● Oversaw study management for in-house and outsourced animal biothreat studies, including study design, proposals, protocol development, budgeting, scheduling, regulatory, and reporting.● Participated in animal model study design, including pathogen natural history, PK/PD, POC, single and multi-dose efficacy, tolerability, and survival studies. ● Interacted with government agencies, including Defense Threat Reduction Agency (DTRA), and the Biomedical Advanced Research and Development Authority (BARDA) to progress studies through drug development.
  • Galleon Pharmaceuticals
    Manager Of Preclinical Outsourcing - Drug Discovery
    Galleon Pharmaceuticals Apr 2013 - May 2014
    ● Identified and collaborated with CRO's and academic laboratories for appropriate preclinical assays for Drug Discovery projects.● Acquired and negotiated quotes, and managed budgets for assigned projects reported directly to the Executive VP of Discovery.● Collaborated with and managed contacts, oversaw shipping, tracked study progress, and reported on a variety of studies including in vitro toxicology screens, receptor and channel profiling, in vivo toxicology, PK, safety studies, cell-based functional assays, general laboratory maintenance, and other relevant projects.
  • Galleon Pharmaceuticals
    Scientist Iii
    Galleon Pharmaceuticals Feb 2008 - May 2014
    Horsham, Pa
    Department of Biology; Drug Discovery & DevelopmentInnovative Respiratory MedicinesScientist III - Nov 2011 - May 2014Scientist I - Feb 2008 - Nov 2011● Communicated and collaborated with colleagues, contributing to the development of an efficient, integrated, high-performance Drug Discovery group in the field of respiratory therapeutics.● Researched and developed appropriate in vivo models to evaluate whole-body and molecular physiology of ventilatory control disease models, effects of compounds on experimental variables, and site of action for the impact on ventilatory control, cardiorespiratory systems, nociception, behavior, and safety profiles of novel compounds.● Participated in the identification and installation of several drug discovery programs, including two programs that led to the founding of 2 clinical drug candidates, one of which was tested in phase I/II clinical trials in 2011 and 2012.● Ran and reported on appropriate drug discovery assays relevant to ventilatory control including plethysmography, telemetry, pulse oximetry, spirometry, arterial blood gases, tail-flick, rotarod, behavioral assays, audio recordings, blood sampling, tissue harvest, and PK/PD studies● Performed small mammal survival surgery and post-operative care, including telemetry surgery (Millar, Inc.), transections, and cannulations.● Authored scientific reports, SOPs, general and IACUC protocols, IND/IMPD reports, manuscripts, and scientific posters.● Attended professional seminars and lectures, and served as an ambassador for the company’s university affiliations at The University of the Sciences in Philadelphia, the University of Virginia, East Carolina University, and the University of Pennsylvania.● Contributed to the overall running of the Drug Discovery and Development group, including operational aspects as a member on various committees.● Trained as a Project Manager and Clinical Research Associate.
  • Gsk
    Bench Scientist
    Gsk Aug 2007 - Dec 2007
    King Of Prussia, Pa
    Cardiovascular Centre of Excellence for Drug Discovery● Participated in a variety of experiments involving cardiovascular and urogenital responses to GSK compound through the use of telemetry blood pressure and biopotential implants in various strains of rodents.● Performed phenotyping and metabolic experiments in knock-out mouse strains. Oversaw and performed dosing and sample processing for PK/PD analysis. ● Actively participated in data analysis and interpretation for project meetings. ● Authored protocols, ran experiments, assisted with surgeries, and performed tissue harvesting.
  • University Of Pennsylvania
    Research Specialist
    University Of Pennsylvania Jul 2005 - Aug 2007
    University Of Pennsylvania - University City, Pa
    Department of Molecular Ophthalmology● Oversaw and performed a variety of experiments involving molecular identification, quantification, and purification of human and rodent DNA/RNA samples, snps, and other PCR-based assays including sequencing and genotyping.● Utilized appropriate bioinformatics techniques including molecular databases and nucleotide/protein alignment tools.● Oversaw all DNA sequencing projects for the department, maintained a genomic DNA library and knock out mouse colony.● Performed tissue culturing, cryosectioning, in situ hybridization and immunoblotting
  • Glaxosmithkline
    Associate Safety Pharmacology Technician
    Glaxosmithkline Jan 2005 - Jun 2005
    King Of Prussia, Pa
    Department of Safety Assessment● Participated in the design and analysis of preclinical safety assessment procedures and monitoring of respiratory and cardiovascular parameters in non-human primates, canines, and rodents using telemetry, plethysmography, and other safety and toxicology assays.● Performed laboratory techniques including dosing, bleeds, tissue harvest, PK/PD, and processing for in vivo studies.
  • The Pennsylvania State University
    Research Assistant
    The Pennsylvania State University Jan 2004 - Dec 2004
    University Park, Pa
    Department of Entomology● Assisted in research on sex pheromone-mediated behavior and peripheral olfactory events in various moth species and other insects.● Oversaw all insect rearing procedures and general laboratory maintenance.
  • Penn State University
    Laboratory Technician
    Penn State University May 2004 - Aug 2004
    University Park, Pa
    Department of Biochemistry● Performed a variety of laboratory procedures including electrophoresis, and plating bacteria and cells.● Prepared solutions and culture plates for cell growth.
  • Brukner Nature Center
    Student Intern In Wildlife Rehabilitation & Environmental Education
    Brukner Nature Center May 2002 - Aug 2002
    Troy, Ohio
    ● Organized, managed, and instructed a variety of environmental education programs for the general public.● Maintained and rehabilitated many species of wild birds, reptiles, and mammals.

Ryan Gruber Skills

Drug Discovery Biotechnology In Vivo Biochemistry Pharmacology Neuroscience Assay Development Immunology Laboratory Drug Development Genetics Clinical Development

Ryan Gruber Education Details

Frequently Asked Questions about Ryan Gruber

What company does Ryan Gruber work for?

Ryan Gruber works for Johnson & Johnson Innovative Medicine

What is Ryan Gruber's role at the current company?

Ryan Gruber's current role is Associate Director, Precision Medicine Oncology Biomarker and Diagnostic Operations.

What is Ryan Gruber's email address?

Ryan Gruber's email address is rb****@****ail.com

What is Ryan Gruber's direct phone number?

Ryan Gruber's direct phone number is +181436*****

What schools did Ryan Gruber attend?

Ryan Gruber attended University Of Maryland Global Campus, University Of Pennsylvania, Penn State University.

What skills is Ryan Gruber known for?

Ryan Gruber has skills like Drug Discovery, Biotechnology, In Vivo, Biochemistry, Pharmacology, Neuroscience, Assay Development, Immunology, Laboratory, Drug Development, Genetics, Clinical Development.

Who are Ryan Gruber's colleagues?

Ryan Gruber's colleagues are Margaret Mccauley, Adrian Tupangiu, Denise Rencevicz, N Akhaya Kumar Dora, Kanu Parmar, Marta Ruberte Casado, Serban Satruc.

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