Ryan Kyger

Ryan Kyger Email and Phone Number

Bioinformatics, Data Science @ Amgen
Ryan Kyger's Location
Thousand Oaks, California, United States, United States
Ryan Kyger's Contact Details

Ryan Kyger work email

Ryan Kyger personal email

n/a
About Ryan Kyger

I am a bioinformatics & data scientist. I have experience programming in R, Python, Linux (bash), SQL, C++. I have experience doing next generation sequencing (NGS) data analysis (variant calling, RNAseq, ATACseq, WGS, WGBS, Illumina, Nanopore, PacBio). I have experience with Frequentist & Bayesian statistical methods. I have molecular biology laboratory & experimental design experience. I have an accredited business management certification. I am capable of working independently or collaboratively in functional & cross-functional teams.

Ryan Kyger's Current Company Details
Amgen

Amgen

View
Bioinformatics, Data Science
Website:
amgen.com
Company phone:
+ 0120-790-549
Ryan Kyger Work Experience Details
  • Amgen
    Data Scientist
    Amgen Mar 2024 - Present
    Thousand Oaks, Ca, Us
  • Amgen
    Associate Scientist (Contracted Via Donatech)
    Amgen Jun 2021 - Mar 2024
    Thousand Oaks, Ca, Us
    • Completed genomic DNA sequence variant analysis using fastp, bwa, GATK, octopus, samtools, bcftools, SnpEff, shinyGO on Illumina short-read whole genome sequence (WGS) data from different CHO cell lines on an AWS EC2 Linux instance to measure genetic differences between the cell lines. • Completed genomic DNA sequence variant analysis using fastp, pbmm2, GATK, pbsv on Pacific Biosciences (PacBio) HiFi long-read whole genome sequence (WGS) data from different CHO cell lines on an AWS EC2 Linux instance to measure genetic differences between the cell lines. • Completed differential expression analysis using a nextflow nfcore rnaseq pipeline (FastQC, STAR, stringtie, salmon), DESeq2, pathfindR on bulk RNAseq data (Illumina) from different CHO cell lines on an AWS EC2 Linux instance to measure mRNA expression differences between the cell lines.• Completed ATACseq analysis of CHO cells using a nextflow nfcore atacseq pipeline, HMMRATAC on an AWS EC2 Linux instance. • Completed Oxford Nanopore long-read structural variant calling using pycoQC, minimap2, NGMLR, SVIM, sniffles, cuteSV on an AWS EC2 Linux instance. • Collaborated with team members to develop an automated variant calling pipeline using fastp, bwa, GATK, octopus, lofreq, samtools, bcftools, SnpEff, that runs on AWS EC2 Linux instances, for protein quality control.• Collaborated with cross-functional team members to develop machine learning models to predict high protein producing CHO cell clones.• Completed de novo assembly of DNA sequences of proteins using MEGAHIT, Flye. • Created heatmaps of Nanostring nCounter gene expression data using R. • Developed an R script that outputs an interactive visualization & regression of mutation frequency vs time data.• Documented code in company GitLab repositories.
  • University Of Nevada, Reno
    Phd Student (Cell & Molecular Biology)
    University Of Nevada, Reno Aug 2018 - Feb 2020
    Reno, Nv, Us
    • Published discovery that myxozoans (parasitic jellyfish) lack cytosine DNA methylation, by analyzing Whole Genome Bisulfite Sequence (WGBS) data (DOI: http://dx.doi.org/10.1093/molbev/msaa214).
  • San Francisco State University
    Master’S Student
    San Francisco State University Aug 2015 - Jun 2017
    San Francisco, Ca, Us
    • Investigated the Endoplasmic Reticulum in D. melanogaster embryos, using molecular biology & fluorescence microscopy.
  • University Of California, Davis
    Undergraduate Student & Laboratory Assistant
    University Of California, Davis Jun 2014 - Jul 2015
    Davis, California, Us
    • Investigated Kinesin-5 motor proteins in S. cerevisiae, using molecular biology, biochemistry, & fluorescence microscopy.

Ryan Kyger Skills

Spyder Ide Bioconductor R Shiny Rnaseq Analysis R Git Public Speaking Linux Microsoft Onenote Sequence Alignment Microsoft Powerpoint Computer Hardware Assembly Data Analysis Listening Biopython Resource Management Microsoft Visual Studio Code Tableau Analytical Reasoning Bayesian Statistics Openrefine Ngs Analysis Microsoft Office Budgeting Microsoft Word Microsoft Excel Bioinformatics Jupyter Time Management R Markdown Sequence Analysis Sql Python Google Cloud Shell Microsoft Power Bi Rstudio Problem Solving Statistics Organization Skills Video Conferencing Shell Scripting Github

Ryan Kyger Education Details

  • San Francisco State University
    San Francisco State University
    Cell/Cellular And Molecular Biology
  • Uc Riverside Extension
    Uc Riverside Extension
    Business Management
  • Uc San Diego Extended Studies
    Uc San Diego Extended Studies
    Applied Bioinformatics
  • University Of California, Davis
    University Of California, Davis
    Cell/Cellular And Molecular Biology

Frequently Asked Questions about Ryan Kyger

What company does Ryan Kyger work for?

Ryan Kyger works for Amgen

What is Ryan Kyger's role at the current company?

Ryan Kyger's current role is Bioinformatics, Data Science.

What is Ryan Kyger's email address?

Ryan Kyger's email address is rk****@****gen.com

What schools did Ryan Kyger attend?

Ryan Kyger attended San Francisco State University, Uc Riverside Extension, Uc San Diego Extended Studies, University Of California, Davis.

What skills is Ryan Kyger known for?

Ryan Kyger has skills like Spyder Ide, Bioconductor, R Shiny, Rnaseq Analysis, R, Git, Public Speaking, Linux, Microsoft Onenote, Sequence Alignment, Microsoft Powerpoint, Computer Hardware Assembly.

Who are Ryan Kyger's colleagues?

Ryan Kyger's colleagues are Adam Biddlecome, Ana Clary, David Scacco, Ao Santiwong, Sean Santillano, Ken Johnson, Galin Spicer.

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