Ryan Neff Email and Phone Number

Primary research goal was to study genes involved in the determination cognitive deficits seen in Down Syndrome (DS) and autism spectrum disorders (ASDs)

- Superuser and primary contact for Ambr250 HT 24-way automated bioreactor system to support the creation and delivery of mammalian cell lines expressing recombinant therapeutic proteins- Team leader of cell line development projects with responsibilities including coordination with team members, alignment with downstream processes, analyzing team data and drawing conclusions/cutoffs, presenting data, and organizing/running associated meetings- Process development for improving… Show more - Superuser and primary contact for Ambr250 HT 24-way automated bioreactor system to support the creation and delivery of mammalian cell lines expressing recombinant therapeutic proteins- Team leader of cell line development projects with responsibilities including coordination with team members, alignment with downstream processes, analyzing team data and drawing conclusions/cutoffs, presenting data, and organizing/running associated meetings- Process development for improving yield and throughput, including: cell sorting for high-expressers; limiting dilution plating; seeding verification by imaging; and basal media and feed evaluations Show less

- Investigated the impact of the oxidative stress-responsive transcription factor Nrf2 on fatty acid binding proteins (FABPs) in lung cells using small molecule Nrf2 activators and siRNA strategies - Developed a cell culture model of COPD exacerbation using flagellin and lipopolysaccharide to mimic bacterial infection in lung epithelial cells and alveolar macrophages, respectively