Ryan Mceachern Email & Phone Number

Boston, MA, US

Amsterdam, NL

Validation Engineer (Contract)Moderna, Norwood, MAJune 2021 - Present

Amsterdam, NL

• Validation Engineer (Contract), Sanofi Genzyme, Framingham, MANov 2020 - May 2021Validation Engineer (Contract), Pfizer, Andover, MA Jan 2020 - Nov 2020Validation Engineer (Contract), Rubius Therapeutics, Smithfield.
• Generated User Requirement Specifications, Risk Assessments and Qualification Protocols/Reports from scratch in support of a new single-use manufacturing facility.
• Operated and qualified the following single-use systems: bioreactors, centrifuges, mixing vessels, LOVO cell processors.
• Commissioned and qualified critical utilities supplied to manufacturing space including clean compressed air, process gas (Nitrogen, Oxygen, Carbon Dioxide) and HVAC systems.
• Commissioned the site building automation system (BAS) used to control air, gas and HVAC systems.
• Utilized DeltaV Distributed Control System to operate process equipment and simulate alarms.

St Louis, Missouri, US

• Validation Engineer (Contract), Pfizer, North Andover, MAJuly 2018 - Dec 2018
• Validation activities required for the modification of an existing suite to introduce a new drug substance
• Partnered with automation and process teams to commission new CIP, SIP, process, and transfer phases
• Drafted and executed installation qualifications, operational qualifications, and CIP/SIP performance qualifications of process tanks, ultrafiltration skids, chromatography skids and associated transfer piping
• Qualified SIP cycles using Kaye datalogger and biological indicators
• Assisted CIP cycle development through specification of flow rates and rinse times required for suitable cleaning

Hatboro, Pennsylvania, US

• Validation Engineer II (Contract), Novo Nordisk US Bio Production Inc., West Lebanon, NH
• Collaborated with cross-functional team (Engineering, Validation, Manufacturing, Automation, Metrology, etc.) on commissioning and qualification for new process area startup
• Executed installation and operational qualification of major production equipment (Bioreactor, homogenizer, microfiltration and ultrafiltration skids, chromatography skids, process tanks, buffer tanks) and.
• Managed Hardest to Clean Area cleaning validation study
• Performed CIP circuit development testing used for cleaning recipe optimization

Hatboro, Pennsylvania, US

• Project Manager / Technical Writer (Contract), Regeneron Pharmaceuticals Inc., Rensselaer, NY April 2017 – September 2017
• Authored SOPs, Work Instructions and Training Evaluations to develop Plant and Clean Utility documentation packages
• Gained an in-depth understanding of Water-For-Injection, Clean Steam, Plant Steam, and Domestic Water systems through close collaboration with plant personnel
• Supplied on-time project deliverables through development of successful timelines and detail-oriented project management
• Presented weekly project reports to client
• Managed the on-boarding process and weekly deliverables of an additional project resourceValidation Engineer I (Contract), Novo Nordisk US Bio Production Inc., West Lebanon, NHJune 2016 – April 2017

Durham, New Hampshire, US

• Developed and executed test scripts focused on synchronization of clocks in networked devices
• Gained valuable industry experience in the formof generating reports and communicating with vendors
• Coded using Tcl and gained familiarity with the Linux Operating System
• Trained incoming employees on testing protocols and scripting

Bolton, Connecticut, US

• Analyzed physical and chemical properties of Simoniz products such as pH, refractive index, viscosity, percent of solids, etc., in order to ensure that the quality requirements of each product were fulfilled.
• Assisted in formula reworking in order to improve the quality and stability of Simoniz products

Durham, New Hampshire, US

• Worked to understand and utilize laccase secretion in "Geobacillus Thermoglucosidasius".
• Techniques include bacterial cell culture, PCR, gDNA extraction, DNA gel electrophoresis, DNA and plasmid isolation, protein purification, molecular cloning

US

• Recognized for impressive item scan time. Fastest store-wide scan time in 2011