Senior Scientist
CurrentSynthesis and downstream process of modified oligonucleotide therapeutics.- Use of the MerMade 12 synthesiser to synthesise hybrid DNA/modified RNA oligonucleotides;- Cleavage from different supports and deprotection of synthesised oligonucleotides;- Purification via anion exchange and/or ion pairing RP preparative HPLCs;- Desalting of the.