LabWare LIMS version 7.0 all the activities regarding master data creation which includes the product, sample plan, item codes, chemicals, inventory, CAS #, Standard solution preparatory, chemical preparatory, instruments verification preparation, LIMS error, discrepancy, and so on, moreover, migration of prepared and modified master data from training server to validation followed by the production server. All the performed activities were documented as per the SOP following GDP, all the documents were stored and maintained till archival to the QA department.Caliber LIMS version 3.5.0 E includes product codes, sample plans, worksheets, instruments, chemicals, standard solution preparation, troubleshooting when required, and batch release from LIMS. All the processed activities were documented according to the SOP and maintained.Microbiological testing i.e. BET analysis, Bioburden, MLT, Media preparation, BET and Bioburden Validation, Media preparation, growth promotion test, inoculum preparation, pure culture handling, cryovials preparation, microorganism isolation obtained from environmental monitoring of classified areas, environment monitoring of classified areas using settle plates, active air sampling, surface and contact monitoring including personnel monitoring using RODAC plates and 90 mm plates, and APC (Air Particle Counter), autoclave operation for media standard cycles and HPHV cycles, Sterility testing, autoclave validation, performance verification of balance, biosafety hood and laminar hood, periodic qualification of incubators refrigerators, water baths, and cooling chambers by using a 21 CFR temperature recorder, periodic cleaning of incubators, refrigerators, freezers, handling of QMS, OOS handling, SOP modification, protocol preparation.