Sabrina Morelli Email and Phone Number

Development of membrane biohybrid systems for the in vitro realization of engineered tissues and/or organs and as potential systems for regenerative medicine.• Characterization of polymeric membranes to be used in Bioartificial Organs. • Isolation of mammalian cells: hepatocytes, neurons • Static and dynamic membrane systems for cell cultures • In vitro development of membrane biohybrid systems for adhesion, proliferation, differentiation and maintenance of the specific… Show more Development of membrane biohybrid systems for the in vitro realization of engineered tissues and/or organs and as potential systems for regenerative medicine.• Characterization of polymeric membranes to be used in Bioartificial Organs. • Isolation of mammalian cells: hepatocytes, neurons • Static and dynamic membrane systems for cell cultures • In vitro development of membrane biohybrid systems for adhesion, proliferation, differentiation and maintenance of the specific functions of cells (hepatocytes, neurons, cheratinocytes, lymphocytes, mesenchimal stem cells).• Development of membrane bioreactors for the in vitro regeneration of liver functions to be used as model systems for drug testing and toxicity as well as for studying metabolic diseases and therapeutic molecules, alternative to animal experimentation• Development of hollow-fiber membrane bioreactors for lymphocyte cultures.• Development of bio-hybrid systems based on neurons and hollow fiber or biodegradable membranes for neuro-biotechnology as in vitro model systems to investigate: -neuronal repair and/or regeneration processes after stress conditions (Oxydative stress) implicated in neurodegenerative diseases; -neuroprotective role of natural moleucules; -neuronal activity in order to highlight useful mechanisms regarding the evolution of adaptive responses and regenerative properties following neurotoxic events. Show less