Sade Ruffin, Ph.D. Email & Phone Number

Washington D.C. Metro Area

Madison, Wisconsin Area

• Provide detailed analysis to support mitigation plans and new product development strategies during design reviews by investigating failures, designing experiments, and integrating literature findings
• Create and implement test strategies using analytical methods to provide technical reports for customer programs
• Lead a cross-functional six sigma statistical analysis project focused on establishing specific modes of product contamination, leading to company-wide strategy to address product degradation; expected $2M cost savings
• Author and publish SOPs and test protocols to streamline laboratory quality with focus on safety, validation, and consistency
• Manage and provide guidance to junior staff by supervising standard test plans, ensuring productivity goals are met, and assisting with equipment repairs

Greater New York City Area

• Developed a model to simulate the effects of synthetic molecules on pulsed-field surface hybridization
• Purified and characterized nucleic acids and proteins using liquid chromatography and spectroscopy techniques
• Performed chemical modification of biomolecules with electrochemical tags to advance real-time biosensor detection methods
• Formulated and oversaw plans for junior researchers, which included experimental design, scientific data evaluation, and comprehensive literature review
• Defined the fundamental principles of a novel DNA biosensor device that suppressed cross-hybridized signals based on the preferential properties of synthetic biomolecules, which improved reaction stringency and reduced.

New York, NY

• Utilized solid-phase capture and MALDI-TOF mass spectrometry to characterize and purify modified nucleotides (3’-N3-dNTPs), during polymerase chain reaction (PCR)
• Integrated protein production and purification methods for peroxy sequencing, later adapted as the laboratory standard
• Made significant contributions in optimizing DNA sequencing by synthesis (SBS) based on cleavable fluorescent nucleotide reversible terminators, resulting in reduced limitations and increase of throughput

Doctor Of Philosophy (Phd), Chemical And Biomolecular Engineering

Activities and Societies: New York Academy of Sciences, National Society of Black Engineers (NSBE)Bio-Interfacial Engineering and.

Master Of Science (M.S.), Chemical Engineering

Activities and Societies: American Institute of Chemical Engineers (AIChe), National Society of Black Engineers (NSBE)Columbia Genome Center

Bachelor Of Science (B.S.), Chemical Engineering