Saifullah Saifullah, Ph.D. Email and Phone Number

Development of RNA editing therapy for neuromuscular disease

Development of RNA editing therapy for neuromuscular disease

Area of Bioscience and Biotechnology, Tsukahara Laboratory, JAIST, JapanMy Ph.D. project is a down-regulation of toxic RNAs for the treatment of disease. Firstly, I have characterized the CRISPR-Cas13a activity using luciferase transcript (FLuc) as a target model. Next, I developed a novel therapeutic strategy particularly for EML4-ALK-positive lung cancer using the CRISPR effector.

Area of Bioscience and Biotechnology, Tsukahara Laboratory, JAIST, JapanI demonstrated an economical DNA chip that can evaluate more than 1,000 Single Nucleotide Polymorphisms (SNPs) at a cost of less than $10 per chip. Based on the achievement I am the first author of two journal articles and one international conference (poster).

Department of Molecular Therapy, National Institute of Neuroscience, NCNP, Tokyo, JapanMy work included the down-regulation of a protein using lentivirus-mediated shRNA and elucidation of its association in murine muscle cell proliferation, differentiation, apoptosis, and autophagy.

Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology (JUST), Jashore-7408, Khulna, BangladeshFor my six months Bachelor thesis, I learned how to conduct a survey from street food vendors about food safety attitudes and microbial evaluation of their vended foods in the laboratory. I am the first author of an international conference (poster).