Sam Bourque Email & Phone Number

Singapore, Sg

Production of oligonucleotides- RNAi• Independently responsible for solid phase synthesis method creation and fast paced production of highly modified oligo with various conjugates using Mermade12 and AKTA OP-100 • Purification and cleanup of synthesized sequences by SAX-HPLC /RP HPLC/ SEC HPLC• Verify acceptable impurity profiles by LC-MS/SEC-HPLC/SAX-HPLC• Lab management, equipment installation, and method creation/qualification of LC-MS and HPLC• Generation of quality process documentation (ELN)• Source and manage inventory of needed reagents and process equipment • Communicate and present key production issues and improvements

Milford, Ma, Us

Managed project planning and development which involves forecasting in materials, creation of production procedures, and process deliverables to meet client demands. • Safety analysis of products and raw materials. • Raw material projections using excel with extensive functionality. • Created GMP manufacturing procedure. • Created GMP manufacturing process materials lists. • Implemented cross site SAP material management software involving development and maintenance. • Implemented controlled change requests (CCRs) for changes in validated processes.

Milford, Ma, Us

Performed GMP manufacturing as an operator in the production of oligonucleotides. • Led, scheduled, and operated on all oligo purification processes. • Led "5s" team, maximizing work efficiency and organization. • Generated new process methods for GMP operations. • Drafted documentation for CAPAs, and exceptions by root cause investigation. • Assisted facilities, engineering, and metrology in material/equipment acquisition and maintenance and implementation. • Developed and led processes in new large-scale Oligo manufacturing lab expansion.