Sameer Joshi, Ph.D. Email & Phone Number
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Sameer Joshi, Ph.D. is listed as Radiochemist at PharmaLogic Holdings Corp., a with 454 employees, based in Columbia, Missouri, United States. AeroLeads shows a matched LinkedIn profile for Sameer Joshi, Ph.D..
Sameer Joshi, Ph.D. previously worked as Postdoctoral Researcher at University Of North Carolina At Chapel Hill and Postdoctoral Research Fellow at Ut Health San Antonio. Sameer Joshi, Ph.D. holds Doctor Of Philosophy - Phd, Organic Chemistry, Cum Laude from University Of Basque Country, Spain.
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About Sameer Joshi, Ph.D.
Doctorate (Organic Chemistry) degreed Organic Chemist with 10+ years of experience in the synthesis of small molecules, Medicinal Chemistry and synthetic methodology. Handling of moisture and air-sensitive reactions for the multi step organic synthesis.(using Glove box) Specialized in Process Chemistry. Large scale synthesis of antibiotic compounds. (>50 grams) Reactions were handled from few milligrams to 100 grams scale. Employed in various coupling reactions, oxidation, reduction, reductive amination and protection–deprotection of various functional groups and name reactions. Development of structure activity relationship (SAR) study for Hit-to Lead molecules in drug discovery. Troubleshoot a wide array of synthetic chemistry issues at the bench scale and apply corrective measures. Understand and apply complex and advanced chemical concepts in a laboratory setting. Collect and consolidate data from multiple sources including laboratory notebooks records and chemical literature to enable evaluation of experimental outcomes by identifying important information, tracing possible causes of problems, and searching for practical solutions. Purification of organic compounds by using column chromatography, Prep-TLC, Prep-Hplc etc. Characterizations of compounds by NMR spectroscopy, LC-MS, GC-MS, HRMS and IR etc.Radiochemist with 5 years of experience in radio labeling small molecules for the potential preclinical research. Synthesis of precursors for the subsequent radio-labeling steps. Excellent problem-solving skills. Bulk of my experience in handling radioisotopes such as 13N, 18F, 11C etc. Specialized in radiolabeling methodology development and radiotracer production under GMP regulation for the diagnosis of neurodegenerative disease. Experience with fully automated synthesis with GE TRACERlabTM FX-N Pro module. Development of Photoredox 18F radiofluorination. (Deoxyfluorination) for the potential preclinical and clinical studies. Prepares written reports on all phases of laboratory and/or field experimental work with limited direction. Experience in writing technical documents using templates, long-term strategic goals and SOP systems. Skilled in purification of radioactive compounds by using semi-preparative Hplc. Quality control of the radioactive products by using Radio-Hplc, Radio-TLC.Synthetic Chemist & Radiochemist Excellent written and oral communication skills as evidence by 10 scientific publications in peer-reviewed International Journals and presentations at international conferences.Please contact me at Email: sameerjoshi94@gmail
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Sameer Joshi, Ph.D. work experience
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Radiochemist
Radiochemist
Postdoctoral Researcher
• Synthesis of small molecules.• Synthesis of 18F labeled novel radiotracers by using photoredox radiofluorination for the potential preclinical studies.
Postdoctoral Research Fellow
• Synthesis of [18F] AV-1451 and [18F] PI-2620 by using automated synthetic process with GE TRACERlabTM FX-N Pro module. • Synthesis of novel F-18 and C-11 radiotracers for the potential diagnosis of neurodegenerative disease. • Synthesis of small molecules for targeting Alpha Synuclein and Tau proteins. Project was supported by Michael J Fox Foundation (MJFF).
Postdoctoral Research Associate
• Synthesis of novel fluorine compounds and their (SAR) studies. Fluorogenic enzymatic assays of those compounds for Histone deacetylation (HDACs) for the development of potential F-18 radiotracer. • Synthesis of heterocyclic compounds for hyper-polarization and MRI imaging agents.• Synthesis of [15N3]Metronidazole Antibiotic in large scale (~54 grams) and synthesis of [15N3]Fluoro Metronidazole.• Synthesis of heterocyclic compounds/antibiotic compounds for the potential hypoxia sensing.•
Postdoctoral Fellow
• Click chemistry of triazoles via Azide-Aldehydes or Ketones [3+2]-cycloaddition reactions in water as a green solvent. • Multi-step synthesis of heterocyclic compounds.
Phd Student
Marie Curie Ph.D. student at CIC biomaGUNE, San Sebastian, Spain October 2013- June 2017Project name: RADIOMI (FP7-PEOPLE-2012-ITN/316882) • Synthesis of 13N labeled Azide• Mechanistic study: Elucidation of most plausible reaction mechanism for the synthesis of 13N-labelled arylazide from diazonium salt. • Synthesis of 13N labeled Triazoles• Synthesis of 13N labeled Tetrazoles• Synthesis of 123I labeled Iododiflunisal.Supervised by Dr. Jordi Llop
Researcher
• Synthesis of various bio-active & heterocyclic compounds. • Reactions were handled from few mg to 100 g scale. • Handling of various reactions such as reductive amination, Suzuki coupling, Buchwald coupling, Sonogashira Coupling and acid-amide coupling on various substrates.• Employed protection–deprotection of various functional groups and dry reactions.
Researcher
• Synthesis of organic compounds.• Synthesis of organic compounds by using heterogeneous catalyst.
Colleagues at PharmaLogic Holdings Corp.
Other employees you can reach at radiopharmacy.com. View company contacts for 454 employees →
Radyofarmasi Derneği
Colleague at Pharmalogic Holdings Corp.Türkiye, Turkey
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Petrit Dema
Colleague at Pharmalogic Holdings Corp.Helsinki, Uusimaa, Finland
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Ágota Szűcs
Colleague at Pharmalogic Holdings Corp.Budapest, Hungary
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Adam Powell
Colleague at Pharmalogic Holdings Corp.Greater Evansville Area, United States
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Keith Brinkman
Colleague at Pharmalogic Holdings Corp.Newburgh, Indiana, United States
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Ágota Szűcs
Colleague at Pharmalogic Holdings Corp.Budapest, Hungary
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Charlie Gruner
Colleague at Pharmalogic Holdings Corp.Evansville, Indiana, United States
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Sameer Joshi, Ph.D. education
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University Of Basque Country, Spain
Frequently asked questions about Sameer Joshi, Ph.D.
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What company does Sameer Joshi, Ph.D. work for?
Sameer Joshi, Ph.D. works for PharmaLogic Holdings Corp..
What is Sameer Joshi, Ph.D.'s role at PharmaLogic Holdings Corp.?
Sameer Joshi, Ph.D. is listed as Radiochemist at PharmaLogic Holdings Corp..
Where is Sameer Joshi, Ph.D. based?
Sameer Joshi, Ph.D. is based in Columbia, Missouri, United States while working with PharmaLogic Holdings Corp..
What companies has Sameer Joshi, Ph.D. worked for?
Sameer Joshi, Ph.D. has worked for Pharmalogic Holdings Corp., University Of North Carolina At Chapel Hill, Ut Health San Antonio, Wayne State University, and National Chemical Laboratory.
Who are Sameer Joshi, Ph.D.'s colleagues at PharmaLogic Holdings Corp.?
Sameer Joshi, Ph.D.'s colleagues at PharmaLogic Holdings Corp. include Radyofarmasi Derneği, Petrit Dema, Ágota Szűcs, Adam Powell, and Keith Brinkman.
How can I contact Sameer Joshi, Ph.D.?
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What schools did Sameer Joshi, Ph.D. attend?
Sameer Joshi, Ph.D. holds Doctor Of Philosophy - Phd, Organic Chemistry, Cum Laude from University Of Basque Country, Spain.
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