Samuel Chen Email & Phone Number

Seattle, Washington, United States

• Developed a novel osmosis-driven biospecimen processing device to efficiently concentrate and purify analytes for research and clinical diagnostics applications• Managed an interdisciplinary team of scientists, engineers, and business professionals to develop commercialization strategies• Built entrepreneurial knowledge on the Lean startup model, competitive analysis, customer discovery, product development, intellectual property protection and medical device regulation• Established partnerships with diagnostic assay developers, assay evaluation agencies, product designers and manufacturers• Conducted periodic meetings with industry partners and advisory board members to deliver progress updates

Atlanta, Georgia, United States

• Developed a microfluidic cell deformability cytometry system for studying cell mechanical responses to high strain, fast timescale deformations • Assessed the effects of mechanical stress in microfluidic processing systems on cell biological responses (e.g., gene expression, exosome secretion)• Integrated a microfluidic mixer with mechanoporation platform to efficiently deliver hard-to-transfect hydrophobic reagents into cells for cell engineering and analytical applications• Designed and fabricated silicon wafers using photolithography and two-photon lithography as microfluidic soft lithography molds• Supervised 10+ undergraduate students to conduct interdisciplinary microfluidic research in cell deformability cytometry, mechanoporation, flow-focusing droplet generation, multiphase mixing, and machine-learning-enabled cell tracking

Seattle, Washington, United States

• Developed an integrated single-cell micro-dispenser system to dispense single cells into microfluidic channels at high precision • Optimized a high-throughput, microfluidic thin-layer chromatographic analysis workflow to characterize lipidomic cell death pathways for cancer drug screening

Seattle, Washington, United States

• Integrated FFPE tumor biopsy sample deparaffinization, cell lysis, protein digestion, and peptide purification procedures into a microfluidic system to improve triple negative breast cancer biomarker discovery workflow on MRM-mass spectrometry• Designed and fabricated novel magnetic test tube racks to increase the temperature-responsive magnetic nanoparticle biomarker capture efficiency

• Designed and prototyped a pulse oximeter with a melanin sensor and a skin tone correction algorithm to enable accurate and non-invasive oxygen saturation measurement across all skin tones• Evaluated stakeholder needs, explored market opportunities, and reviewed potential regulatory pathways

Seattle, Washington, United States

• Compiled ongoing updates on testing methodologies, molecular targets, regulatory status, and procurement pathways for COVID-19 diagnostics dashboards with over fifteen thousand unique visits during the pandemic• Evaluated existing COVID-19 diagnostic manufacturing capacity, conducted regulatory analysis to identify optimal channels to market, and developed strategies to increase supply for future epidemics

Doctor Of Philosophy - Phd, Bioengineering

Bachelor Of Science - Bs, Mechanical Engineering; Minor In Chemistry