Samuel Chen Email & Phone Number

Seattle, Washington, United States

• Developed a novel osmosis-driven biospecimen processing device to efficiently concentrate and purify analytes for research and clinical diagnostics applications
• Managed an interdisciplinary team of scientists, engineers, and business professionals to develop commercialization strategies
• Built entrepreneurial knowledge on the Lean startup model, competitive analysis, customer discovery, product development, intellectual property protection and medical device regulation
• Established partnerships with diagnostic assay developers, assay evaluation agencies, product designers and manufacturers
• Conducted periodic meetings with industry partners and advisory board members to deliver progress updates

Atlanta, Georgia, United States

• Developed a microfluidic cell deformability cytometry system for studying cell mechanical responses to high strain, fast timescale deformations
• Assessed the effects of mechanical stress in microfluidic processing systems on cell biological responses (e.g., gene expression, exosome secretion)
• Integrated a microfluidic mixer with mechanoporation platform to efficiently deliver hard-to-transfect hydrophobic reagents into cells for cell engineering and analytical applications
• Designed and fabricated silicon wafers using photolithography and two-photon lithography as microfluidic soft lithography molds
• Supervised 10+ undergraduate students to conduct interdisciplinary microfluidic research in cell deformability cytometry, mechanoporation, flow-focusing droplet generation, multiphase mixing, and.

Seattle, Washington, United States

• Developed an integrated single-cell micro-dispenser system to dispense single cells into microfluidic channels at high precision
• Optimized a high-throughput, microfluidic thin-layer chromatographic analysis workflow to characterize lipidomic cell death pathways for cancer drug screening

Seattle, Washington, United States

• Integrated FFPE tumor biopsy sample deparaffinization, cell lysis, protein digestion, and peptide purification procedures into a microfluidic system to improve triple negative breast cancer biomarker discovery workflow.
• Designed and fabricated novel magnetic test tube racks to increase the temperature-responsive magnetic nanoparticle biomarker capture efficiency

• Designed and prototyped a pulse oximeter with a melanin sensor and a skin tone correction algorithm to enable accurate and non-invasive oxygen saturation measurement across all skin tones
• Evaluated stakeholder needs, explored market opportunities, and reviewed potential regulatory pathways

Seattle, Washington, United States

• Compiled ongoing updates on testing methodologies, molecular targets, regulatory status, and procurement pathways for COVID-19 diagnostics dashboards with over fifteen thousand unique visits during the pandemic
• Evaluated existing COVID-19 diagnostic manufacturing capacity, conducted regulatory analysis to identify optimal channels to market, and developed strategies to increase supply for future epidemics

Doctor Of Philosophy - Phd, Bioengineering

Bachelor Of Science - Bs, Mechanical Engineering; Minor In Chemistry