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Sam Brook Email & Phone Number

Lab and Facilities Operations at Arvinas
Location: Fairfield, Connecticut, United States 7 work roles 4 schools
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Current company
Role
Lab and Facilities Operations
Location
Fairfield, Connecticut, United States
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Who is Sam Brook? Overview

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Quick answer

Sam Brook is listed as Lab and Facilities Operations at Arvinas, a company with 360 employees, based in Fairfield, Connecticut, United States. AeroLeads shows a matched LinkedIn profile for Sam Brook.

Sam Brook previously worked as Senior Associate Scientist and Laboratory Manager at Alphina Therapeutics and Senior Research Associate at Phasebio Pharmaceuticals, Inc.. Sam Brook holds Bachelor'S Degree, Neuroscience from Skidmore College.

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Arvinas

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Profile bio

About Sam Brook

Accomplished Research Biologist with extensive experience in managing BSL2-certified labs, optimizing lab operations, and driving drug discovery projects. Proven ability to establish and maintain high-functioning lab environments, manage critical supplies, and coordinate with key vendors.Expert in establishing and maintaining high-functioning lab environments, managing critical supplies, and coordinating with key vendors to ensure seamless operations and project success.Currently, I lead the development of a state-of-the-art BSL2-certified lab, significantly advancing small molecule compounds through SAR and lead optimization. My strategic management of CRO partnerships has been instrumental in conducting comprehensive ADME/PK studies, propelling our drug candidates closer to clinical application. I excel at building and nurturing relationships with CROs and key vendors, ensuring collaborative efforts are aligned with our research goals and operational needs.At PhaseBio, Inc., I pioneered the design of novel fusion peptides using proprietary ELP biopolymer technology, contributing to a robust pipeline of protein therapeutics and biologics. My work in protein engineering has been pivotal in advancing therapeutic platforms from concept to preclinical trials.My professional focus is on leveraging cutting-edge screening technologies and innovative research approaches to accelerate therapeutic development. Through strategic laboratory management and comprehensive drug discovery expertise, I am dedicated to advancing novel treatments that address critical unmet medical needs.I am passionate about driving scientific innovation and fostering collaborative environments to develop groundbreaking treatments. My goal is to continue contributing to the advancement of personalized medicine and improving patient outcomes.

Current workplace

Sam Brook's current company

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Arvinas
Arvinas
Lab and Facilities Operations
Fairfield, CT, US
Website
Employees
360
AeroLeads page
7 roles · 16 years

Sam Brook work experience

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Lab And Facilities Operations

Fairfield, CT, US

Senior Associate Scientist And Laboratory Manager

New Haven, CT, US

In-House Screening and Discovery: Orchestrate end-to-end development of a comprehensive small molecule screening funnel, directing in vitro assays, ADME/PK profiling, and in vivo efficacy testing to advance compounds through SAR and lead optimization.Lab Operations Management: Pioneered the buildout of a BSL2-certified oncology drug discovery lab from.

Senior Research Associate

Phasebio Pharmaceuticals, Inc.

Engineered recombinant fusion proteins that advanced to preclinical trials, contributing to the development of biopharmaceutical product candidates.Instrumental in the development of PhaseBio's proprietary ELP biopolymer technology platform, a recombinant biopolymer that extends the circulating half-life of protein therapeutics. Contributed significantly.

Sep 2019 - Apr 2022

Laboratory Technician - Human Oncology & Pathogenesis Program, Baselga Lab

New York, NY, US

Contributed to the development and establishment of a nanoparticle-based targeted drug delivery system for delivery of small molecule kinase inhibitors the tumor microenvironment.- achieved tumor-specific drug delivery resulting in durable control of tumor growth - enhanced efficacy by combined administration of radiation therapy and anti-tumor kinase.

2013 - 2016 ~3 yrs

Research Assistant - Neurosurgical Laboratory For Translational Braim Tumor And Stem Cell Research

New York, NY, US

Applied xenograft disease models to explore novel treatment options for patients with high grade glioma Extraction, purification, and culture of tumor stem cells derived from human glioma tissue; characterization of potential therapeutic agents via analysis of gene and protein expression

2013 - 2013

Laboratory Technician - Stem Cell & Regenerative Biology, Macklis Lab

Cambridge, Massachusetts, US

Investigated the developmental biology (and sub-type specification) of neocortical projection neurons; experiments aimed to elucidate the molecular genetic controls underlying segmental specificity in corticospinal projection neurons.Performed mechanistically-relevant studies using transgenic mouse models and engineered cell lines; Provided support to the.

2012 - 2013 ~1 yr

Research Assistant - Inflammation & Allergic Disease Research

US

Studied mast cell function and immune response in a rodent model of asthma by performing preclinical studies of asthma pathophysiology including in vivo drug treatment, bronchoalveolar lavage, tail vein injection, organ dissection to harvest and isolate murine HSCs, culturing these cells for in vitro characterization, targeted differentiation of stem cells.

2010 - 2010
Team & coworkers

Colleagues at Arvinas

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4 education records

Sam Brook education

Bachelor'S Degree, Neuroscience

Skidmore College

Education record

Temple University

Graduate School Of Biomedical Science, Biomedical Sciences, General

Rutgers University

Neuroscience

Skidmore College
FAQ

Frequently asked questions about Sam Brook

Quick answers generated from the profile data available on this page.

What company does Sam Brook work for?

Sam Brook works for Arvinas.

What is Sam Brook's role at Arvinas?

Sam Brook is listed as Lab and Facilities Operations at Arvinas.

Where is Sam Brook based?

Sam Brook is based in Fairfield, Connecticut, United States while working with Arvinas.

What companies has Sam Brook worked for?

Sam Brook has worked for Arvinas, Alphina Therapeutics, Phasebio Pharmaceuticals, Inc., Memorial Sloan Kettering Cancer Center, and Joan & Sanford I. Weill Medical College Of Cornell University.

Who are Sam Brook's colleagues at Arvinas?

Sam Brook's colleagues at Arvinas include Dustin Revell, Chu Ngo, Goutham Pattabiraman, Peter Nower, and William Butcher.

How can I contact Sam Brook?

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What schools did Sam Brook attend?

Sam Brook holds Bachelor'S Degree, Neuroscience from Skidmore College.

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