Samyuktha Suresh, Phd Email and Phone Number

- Lead and executed in vitro experiments to evaluate drug synergy between PARP and PRMT5inhibitors for the treatment of triple-negative breast cancer using cell-based drug combinationassays.- Developed stable knockout cell lines using CRISPR/Cas9 to screen potential drug targets,contributing to preclinical drug development and validation.- Mentored junior researchers, including training an undergraduate summer intern on drugsensitivity assays, fostering a collaborative and educational lab environment.- Expertise in cell culture, flow cytometry, qPCR, and Western blotting, providing strongfoundational skills for validating targets, screening drug candidates, and determiningmechanisms of action (MoA).

- Performed literature search on protein-arginine methylation approaches and techniques todevelop the research plan for my Ph.D. thesis.- Led collaborative research projects on protein methylation in breast cancer, resulting inmultiple publications and successful identification of novel therapeutic targets.- Designed and validated in vitro and in vivo assays to explore the role of PRMT1 andPRMT5 in breast cancer, contributing to strategic drug development plans .- Analyzed and interpreted data from cancer databases and experimental results.- Prepared comprehensive reports and communicated findings to both internal teams andexternal collaborators.- Supervised and mentored graduate and undergraduate students, enhancing the team'sexpertise in molecular biology and cancer research techniques.

- Managed and organized the abstracts received for the conference.- Contacted potential sponsors for obtaining funding.- Managed the registration desk during the conference.

Master's Thesis under Dr Rupak Datta at the Lysosome Biology and Related Diseases group.Project Title: Age-related changes in Beta-glucuronidase and other lysosomal genes.

Worked on 'Function of the Pentatrico-peptide repeat protein, Ppr1, in the mitochondria of Schizosaccaromyces pombe'

Worked on 'Mitochondrial Haplogroups and their role in obesity in the Balinese population'

Worked on a project on Gene Cloning and Expression.

Worked in the Department of Molecular Reproduction,Development and Genetics and got exposed to basic techniques in the field of Molecular Biology and Biochemistry.