I’m a passionate scientist fueled by a love for uncovering the mysteries of the human body, especially the cellular and molecular mechanisms that drive chronic diseases, cancer, and autoimmune conditions. With over six years of hands-on experience in biomedical science, spanning molecular and cell biology, toxicology, and bioinformatics, I’ve had the privilege of working alongside a dynamic, multidisciplinary team, sharpening my skills in problem-solving, leadership, time management, and scientific communication. I thrive on challenges that push me to grow, and I’m always excited about the next breakthrough.In my experience as a postdoc, I focused on finding biomarkers and novel therapeutic targets to slow or halt the progression of chronic liver diseases, like MAFLD. This journey has been a mix of learning and discovery, as I’ve expanded my expertise to include techniques like organoids and extracellular vesicle analysis, powerful tools for exploring disease progression in liver and beyond. I’m driven to develop solutions with real-world impact, knowing each finding could be a game-changer for countless lives.And now, in my latest adventure, I’ve joined Johnson & Johnson as a scientist working on cell and gene therapies. Here, I’ve found a new fascination with the incredible potential of microorganisms as tools to fight diseases, from cancer to rare genetic disorders. I’m learning the ins and outs of CAR-T cells, uncovering the complexities of immune cells, and discovering just how powerful viral vectors can be for delivering information with precision. Although these technologies are still emerging, I’m thrilled to be part of their advancement and can’t wait to tackle the next challenge they bring my way.If you’re interested in connecting, I’d love to chat and share ideas, or geek out over the endless possibilities in science!
Umcg Research
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Postdoctoral ResearcherUmcg ResearchNetherlands -
ScientistJohnson & Johnson Innovative Medicine Apr 2024 - PresentLeiden, South Holland, Netherlands• Managed multiple stability studies for novel products, including plasmids and vaccines (e.g., for COVID-19, Ebola, and influenza viruses), during clinical development.• Developed and reviewed stability plans and reports under Good Manufacturing Practices (GMP) and Good Documentation Practices (GDP).• Defined storage conditions following regulatory guidelines and ensured product stability during manufacturing transitions.• Presented strategies and results at scientific meetings and contributed to cross-functional project discussions.• Gained knowledge in CAR-T cells, adeno-associated viruses (AAVs), and lentiviral vector biology, as well as experience in identifying attributes that directly impact therapeutic outcomes in cancer and other genetic disorder-related diseases.• Acquired knowledge in addressing the challenges of treating solid and liquid cancers using next-generation technologies such as cell therapy.• Acquired knowledge in defining CQAs essential for product development, ensuring both safety and efficacy in gene and cell therapy applications.• Familiar with regulatory requirements and guidelines for biopharmaceutical development (FDA, EMA, ICH)• Managed multiple stakeholders across departments, ensuring the timely completion of technical documentation and alignment of goals.• Facilitated cross-functional collaboration to streamline processes, improve project outcomes, and drive the advancement of clinical products. -
Postdoctoral ResearcherUmcg Research Oct 2021 - PresentNetherlands -
Postdoctoral ScientistUmcg Research Oct 2021 - Feb 2024Groningen, Netherlands -
Phd StudentUmcg Research Jan 2018 - Feb 2023Groningen, Netherlands- Established, authored, and concurrently developed the experimental designs for four original projects, honing project management skills, including time management and research project progression.- Executed experimental designs on primary cells as macrophages, myofibroblasts (HSC), hepatocytes, PBMC among others as well in liver organoids developed from liver adult stem cells, gaining extensive experience in cell culture and cell isolation and various cellular and molecular techniques.- Developed, analyzed, and validated the cytotoxic effects of various compounds in in vitro studies, and documented and recorded results in an electronic laboratory notebook. -
Phd CandidateUniversidad Autónoma De Aguascalientes Jan 2018 - Sep 2021MexicoGained fellowship to perform PhD studies.- Designed and authored two original research projects for in vivo and in vitro studies and established in vivo studies focused on liver fibrosis. - Conducted experiments for both in vitro and in vivo studies and analyzed results and authored comprehensive reports. - Published research manuscripts and presented findings at international conferences.- Standardized, implemented, and developed experimental protocols for the isolation of primary liver cells in a laboratory lacking prior experience in cell isolation.- Provided supervision to undergraduate students. -
University LecturerUvm Feb 2019 - Dec 2019Aguascalientes, Mexico- Developed and implemented dynamic lesson plans, fostering student engagement and improving overall comprehension.- Led initiatives to integrate technology into the science curriculum, enhancing interactive learning experiences.- Collaborated with a cross-functional team to revise and update the biology curriculum, ensuring alignment with educational standards.- Successfully implemented project-based learning activities, resulting in a 15% improvement in student performance on standardized tests.- Actively participated in ongoing professional development, attending workshops on modern teaching methodologies and incorporating innovative strategies into daily instruction.- Demonstrated effective classroom management skills, creating a positive and inclusive learning environment.- Initiated and coordinated after-school science club, providing students with additional opportunities for hands-on learning and exploration.- Regularly communicated with parents to provide updates on student progress and address any concerns promptly. -
College LecturerUniversidad Del Valle De México Aug 2017 - Jul 2018Aguascalientes, MexicoLaboratory, Mathematics, chemistry, physics. -
University LecturerUniversidad Cuauhtémoc Plantel Aguascalientes Jul 2017 - Jan 2018Aguascalientes, MexicoBiochemistry, Research Methodology -
University LecturerUniversidad De Guadalajara Feb 2017 - Jul 2017Guadalajara, Jalisco, MexicoToxicology lecture -
Laboratory ManagerMicroanalisis De Occidente Jul 2016 - May 2017Guadalajara, Mexico Metropolitan AreaEnvironmental Toxicology Lab- Conducted comprehensive tests and experiments, analyzing environmental samples to identify and quantify contaminants.- Proficiently operated and maintained a diverse range of laboratory instruments crucial for precise toxicology analysis.- Interpreted and assessed data derived from experiments, drawing insightful conclusions about environmental risks and impacts.- Demonstrated unwavering commitment to safety by strictly adhering to protocols during the handling and disposal of hazardous materials.- Maintained meticulous records of experiments, procedures, and results, ensuring accuracy and accessibility for future reference.- Collaborated seamlessly with team members to effectively achieve research goals and objectives, fostering a productive and cooperative work environment.- Ensured compliance with environmental regulations and standards, demonstrating a strong understanding of the regulatory landscape.- Identified challenges within experiments and proposed innovative solutions, contributing to continuous process improvement.- Communicated findings and results effectively to colleagues, supervisors, and audiences at conferences, showcasing strong presentation and interpersonal skills. -
InvestigadorUniversidad Autónoma De Aguascalientes Jan 2015 - Jun 2016Aguascalientes
Sandra A. Serna S. Education Details
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Phd Medical Science -
Ciencias En El Área De Toxicología -
Instituto Tecnológico De AguascalientesIngeniería Química
Frequently Asked Questions about Sandra A. Serna S.
What company does Sandra A. Serna S. work for?
Sandra A. Serna S. works for Umcg Research
What is Sandra A. Serna S.'s role at the current company?
Sandra A. Serna S.'s current role is Postdoctoral Researcher.
What schools did Sandra A. Serna S. attend?
Sandra A. Serna S. attended University Of Groningen, Universidad Autónoma De Aguascalientes, Universidad Autónoma De Aguascalientes, Instituto Tecnológico De Aguascalientes.
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