Sandra A. Serna S. Email & Phone Number

Netherlands

Netherlands

Leiden, South Holland, Netherlands

• Managed multiple stability studies for novel products, including plasmids and vaccines (e.g., for COVID-19, Ebola, and influenza viruses), during clinical development.• Developed and reviewed stability plans and reports under Good Manufacturing Practices (GMP) and Good Documentation Practices (GDP).• Defined storage conditions following regulatory guidelines and ensured product stability during manufacturing transitions.• Presented strategies and results at scientific meetings and contributed to cross-functional project discussions.• Gained knowledge in CAR-T cells, adeno-associated viruses (AAVs), and lentiviral vector biology, as well as experience in identifying attributes that directly impact therapeutic outcomes in cancer and other genetic disorder-related diseases.• Acquired knowledge in addressing the challenges of treating solid and liquid cancers using next-generation technologies such as cell therapy.• Acquired knowledge in defining CQAs essential for product development, ensuring both safety and efficacy in gene and cell therapy applications.• Familiar with regulatory requirements and guidelines for biopharmaceutical development (FDA, EMA, ICH)• Managed multiple stakeholders across departments, ensuring the timely completion of technical documentation and alignment of goals.• Facilitated cross-functional collaboration to streamline processes, improve project outcomes, and drive the advancement of clinical products.

Netherlands

Groningen, Netherlands

Groningen, Netherlands

- Established, authored, and concurrently developed the experimental designs for four original projects, honing project management skills, including time management and research project progression.- Executed experimental designs on primary cells as macrophages, myofibroblasts (HSC), hepatocytes, PBMC among others as well in liver organoids developed from liver adult stem cells, gaining extensive experience in cell culture and cell isolation and various cellular and molecular techniques.- Developed, analyzed, and validated the cytotoxic effects of various compounds in in vitro studies, and documented and recorded results in an electronic laboratory notebook.

Mexico

Gained fellowship to perform PhD studies.- Designed and authored two original research projects for in vivo and in vitro studies and established in vivo studies focused on liver fibrosis. - Conducted experiments for both in vitro and in vivo studies and analyzed results and authored comprehensive reports. - Published research manuscripts and presented findings at international conferences.- Standardized, implemented, and developed experimental protocols for the isolation of primary liver cells in a laboratory lacking prior experience in cell isolation.- Provided supervision to undergraduate students.

Aguascalientes, Mexico

- Developed and implemented dynamic lesson plans, fostering student engagement and improving overall comprehension.- Led initiatives to integrate technology into the science curriculum, enhancing interactive learning experiences.- Collaborated with a cross-functional team to revise and update the biology curriculum, ensuring alignment with educational standards.- Successfully implemented project-based learning activities, resulting in a 15% improvement in student performance on standardized tests.- Actively participated in ongoing professional development, attending workshops on modern teaching methodologies and incorporating innovative strategies into daily instruction.- Demonstrated effective classroom management skills, creating a positive and inclusive learning environment.- Initiated and coordinated after-school science club, providing students with additional opportunities for hands-on learning and exploration.- Regularly communicated with parents to provide updates on student progress and address any concerns promptly.

Aguascalientes, Mexico

Laboratory, Mathematics, chemistry, physics.

Aguascalientes, Mexico

Biochemistry, Research Methodology

Guadalajara, Jalisco, Mexico

Toxicology lecture

Guadalajara, Mexico Metropolitan Area

Environmental Toxicology Lab- Conducted comprehensive tests and experiments, analyzing environmental samples to identify and quantify contaminants.- Proficiently operated and maintained a diverse range of laboratory instruments crucial for precise toxicology analysis.- Interpreted and assessed data derived from experiments, drawing insightful conclusions about environmental risks and impacts.- Demonstrated unwavering commitment to safety by strictly adhering to protocols during the handling and disposal of hazardous materials.- Maintained meticulous records of experiments, procedures, and results, ensuring accuracy and accessibility for future reference.- Collaborated seamlessly with team members to effectively achieve research goals and objectives, fostering a productive and cooperative work environment.- Ensured compliance with environmental regulations and standards, demonstrating a strong understanding of the regulatory landscape.- Identified challenges within experiments and proposed innovative solutions, contributing to continuous process improvement.- Communicated findings and results effectively to colleagues, supervisors, and audiences at conferences, showcasing strong presentation and interpersonal skills.

Aguascalientes

Phd Medical Science

Doctor Of Philosophy - Phd, Biology/Biological Sciences, General, Phd

Maestría, Ciencias En El Área De Toxicología

Grado En Ingeniería, Ingeniería Química