Sanghoon Lee Email and Phone Number
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Throughout my career, I have extensively explored the fields of Bioinformatics, Cancer Genomics, Cancer Biology, multi-omics data analyses, and prediction modeling. My current research focuses on analyzing vast genomic datasets, including single-cell RNA-seq, bulk RNA-seq, ATAC-seq, Cut&Run-seq, Whole Exome Sequencing (WXS), and Whole Genome Sequencing (WGS), to uncover associations with clinical and phenotypic data of cancer patients.I leverage a wide array of computational analysis tools and statistical programming languages, such as R, Perl, and Shell scripting within Unix/Linux server environments and High-Performance Computing (HPC) platforms. My expertise extends to accessing and utilizing various genomic databases, including ICGC, GDC, EGA, GDSC, CCLE, dbGaP, GEO, cBioPortal, and the Single Cell Atlas, to acquire and analyze data in formats like CEL, fastq, BAM, SAM, VCF, and more.While I have not developed NGS-based software directly, I have significant experience in designing and optimizing such software for variant calling, detecting somatic mutations, gene fusions, gene rearrangements (structural variants), copy number variations (CNVs), and extracting gene expression data. I have integrated multi-omics data and applied them to therapeutic response prediction algorithms, machine learning models, and AI-based models (such as Autoencoder). My extensive knowledge and experience across various scientific disciplines enable me to collaborate effectively with experts in Bioinformatics, Cancer Genomics and Biology. This interdisciplinary approach allows me to successfully contribute to and fulfill research projects, driving forward our understanding and treatment of cancer.
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Postdoctoral ResearcherUniversity Of PittsburghPittsburgh, Pa, Us -
Sr. Research ScientistNyu Langone Health Aug 2024 - PresentNew York, Ny, UsA high-throughput single cell whole genome sequencing (scWGS) for clonal decomposition, DNA replication states, and subclonal mutations. -
Postdoctoral ResearcherUniversity Of Pittsburgh Aug 2021 - Aug 2024Pittsburgh, Pa, Us -
Graduate StudentUniversity Of Pittsburgh Jul 2015 - Apr 2021Pittsburgh, Pa, UsResearch1: An Algorithm for Direct Causal Learning of Influences on Patient Outcomes Research2: Modeling miRNA-mRNA Interactions That Cause Phenotypic Abnormality in Breast Cancer PatientsResearch3: Landscape analysis of adjacent gene rearrangements reveals BCL2L14–ETV6 gene fusions in more aggressive triple-negative breast cancer -
Lab TechnicianUniversity Of Utah School Of Medicine Oct 2012 - Feb 2015Salt Lake City, Ut, Us• Research: Identification of master or transcription regulators that regulate White or Brown Adipose Tissue (WAT or BAT) differentiation. • Data analysis: RNA-seq data normalization and clustering analysis; examine signal pathway in BAT thermogenesis. -
Research AssistantUniversity Of Utah Health Aug 2010 - May 2012Salt Lake City, Utah, UsDepartment of Biomedical Informatics, Program in Personalized Healthcare, University of UtahTitle: Structuring genomic variant data for the electronic health record (EHR)o Designed and developed an automatic software tool to annotate genomic variant data in text and XML format of Genome Variation Format (GVF), which is a standard genomic variation file format and uses standardized terms and relationships for whole genomic sequence and variants from the Sequence Ontology.o Integrated genomic variant data in HL7 CDA Genetic Test Report Template. -
Research CoordinatorVeteran Affairs Clinic Jan 2010 - Dec 2011Center for Health Information and Research (CHIR) Information Extraction Methods and Ejection Fraction• Coordinated IRB and R&D approval among the sites. • Annotated clinical concepts from clinical free text using annotation tools, such as Knowtator and eHOST.
Sanghoon Lee Skills
Sanghoon Lee Education Details
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University Of PittsburghBiomedical Informatics -
University Of UtahBiomedical Informatics
Frequently Asked Questions about Sanghoon Lee
What company does Sanghoon Lee work for?
Sanghoon Lee works for University Of Pittsburgh
What is Sanghoon Lee's role at the current company?
Sanghoon Lee's current role is Postdoctoral Researcher.
What is Sanghoon Lee's email address?
Sanghoon Lee's email address is sa****@****ail.com
What schools did Sanghoon Lee attend?
Sanghoon Lee attended University Of Pittsburgh, University Of Utah.
What skills is Sanghoon Lee known for?
Sanghoon Lee has skills like Bioinformatics, Microsoft Powerpoint, Microsoft Word, Data Analysis, Molecular Biology, Genomic Data Analysis, Java, R, Perl, Cell Culture, Biochemistry.
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