Developing & executing high-level Analytical Research strategies, making high-stakes decisions and overcoming complex business challenges using experience-backed judgment, strong work ethics and irreproachable integrityReviewing reports, monitoring scientific staff and inter-department coordination; performing routine analysis in HPLC, GC, GCHS and Wet lab activity; assisting in chemical analysis of API, intermediates & raw materials and purity analysis by auto sampler GCExecuting… Show more Developing & executing high-level Analytical Research strategies, making high-stakes decisions and overcoming complex business challenges using experience-backed judgment, strong work ethics and irreproachable integrityReviewing reports, monitoring scientific staff and inter-department coordination; performing routine analysis in HPLC, GC, GCHS and Wet lab activity; assisting in chemical analysis of API, intermediates & raw materials and purity analysis by auto sampler GCExecuting reaction monitoring and raw materials analysis by HPLC, GC & GCHSSpearheading continual excellence in execution of manufacturing schedules while developing resource requirement plans to meet the growth of the businessProviding raw data documentation, assessing and interpreting outcomes from sophisticated but established methodologies or processes, and reviewing and confirming raw data produced by others via eLn / LNBExecuting compendia method verification of analytical methods for supporting stabilities studies and implementing 5S and maintenanceAdministering queries related to Regulatory affairs & customers and regular analysis including water content, loss on drying, residue on ignition, heavy metals, volumetric titrations colour value and chromatography developmentCreating and sustaining a dynamic environment that fosters the development opportunities and motivates the high performance amongst the group Managing proper maintenance of instrument logbooks and column books as per gmp and all type of analysis online entry by using Bio via ELN.INSTRUMENT HANDLED: (i) HPLC (ii) GC& GCHS(iii)GCMS (Agilent & Thermo ) (iv)Ion Chromatography (Metrohm) (v) AT-IR Spectrophotometer (Agilent)(vi)UV-Visible Spectrophotometer (Perkin Elmer)(vii) Auto Titrator (Metrohm)(viii)Karl-fischer Titrator (Metrohm)(x) LCHRMS (Thermo) Show less

 Calibration of Instruments like HPLC, pH meter, KF Titrator and Weighing Balances as per SOP.  Co-ordination with vendor for completion of preventive maintenance of lab instruments as per GLP In-process samples testing by HPLC (includes purity and Assay analysis).  Routine analysis for Moisture content & Melting point analysis.  Perform Method development and HPLC monitoring support for API, Pfizer network support Impurities and early stage development drugs as required… Show more  Calibration of Instruments like HPLC, pH meter, KF Titrator and Weighing Balances as per SOP.  Co-ordination with vendor for completion of preventive maintenance of lab instruments as per GLP In-process samples testing by HPLC (includes purity and Assay analysis).  Routine analysis for Moisture content & Melting point analysis.  Perform Method development and HPLC monitoring support for API, Pfizer network support Impurities and early stage development drugs as required.  Generation and maintenance of quality records in line with ALCOA principles. Instruments Handled: • HPLC - Agilent (Software: Open lab)• KF Titration - Metrohm• pH Meter -Metrohm• Combiflash EZ Prep - Teledyne ISCO • Melting Point - Buchi• Semi-micro balance –Sartorius Show less

Process Development for Zolmitriptan, Sumatriptan succinate, Levofloxacin hemihydrate and Succinyl choline chloride.  Performing Literature search and identifying various synthetic routes. Ability to execute chemical reactions with appropriate laboratory equipment and purification techniques. Knowledge on scale up of chemical Reactions Interpretation of Analytical results and propose cost effective process improvements for API (quality, yield, cost etc) Purification… Show more Process Development for Zolmitriptan, Sumatriptan succinate, Levofloxacin hemihydrate and Succinyl choline chloride.  Performing Literature search and identifying various synthetic routes. Ability to execute chemical reactions with appropriate laboratory equipment and purification techniques. Knowledge on scale up of chemical Reactions Interpretation of Analytical results and propose cost effective process improvements for API (quality, yield, cost etc) Purification of compounds by manual/automated column chromatography and re-crystallization techniques  Record observations of experiments, results, utilization of resources and other activities related to the reaction in the laboratory or e-notebook in a timely manner. Responsible for ensuring the instrument/equipment are calibrated, undergone privative maintenance. Supporting KGL/MS&T departments in resolving all the issues during scale up and suggest modifications in order to develop a scalable and robust process. Designing experiments in order to develop safest, scalable and robust process as per process development for API (lab feasibility, optimization, lab validation, CPP, validation in Commercial plants.) Good experience in process validations in lab and commercialization in plant.  Highly motivated, innovative and having good communication and interpersonal skill. To responsible for assisting regulatory queries in EDQM, Investigation, etc Show less