Sara Bertuzzi Email & Phone Number

Monza, Lombardy, Italy

Pharmaceutical Development Services (PDS) Project Manager I

Greater Bilbao Metropolitan Area

Postdoctoral scientist between the Chemical Glycobiology Lab and the Cancer Immunology and Immunotherapy Lab. Valorization of drug candidates for cancer immunotherapy.

Bilbao, Basque Country, Spain

Scientist in Jesús Jiménez-Barbero’s lab (Chemical Glycobiology lab). International double doctorate obtained with honors. PhD in cotutelle between the University of Basque Country (Synthetic and Industrial Chemistry program) and the University of Milano-Bicocca (Converging Technologies for Biomolecular Systems program). Research project focused on exploring molecular recognition events of biomedical interest involving glycans. Structure-based and fragment-based drug… Show more Scientist in Jesús Jiménez-Barbero’s lab (Chemical Glycobiology lab). International double doctorate obtained with honors. PhD in cotutelle between the University of Basque Country (Synthetic and Industrial Chemistry program) and the University of Milano-Bicocca (Converging Technologies for Biomolecular Systems program). Research project focused on exploring molecular recognition events of biomedical interest involving glycans. Structure-based and fragment-based drug discovery were applied targeting different lectin-sugar systems, selected considering their involvement in pathological phenomena (cancer and infectious diseases mainly). The fine details of the binding events have been decoded employing a multidisciplinary approach (NMR, ITC, cryo-EM, MD simulations, FACS, and genomic engineering) from the structural, conformational, and dynamic points of view. Show less

Bilbao, Basque Country, Spain

Junior Scientist in Jesús Jiménez Barbero's group (Chemical Glycobiology Lab).Project centered on deciphering the crucial molecular recognition of blood group antigens by human receptors.

Copenhagen Metropolitan Area

Visiting Researcher at the Copenhagen Center for Glycomics (University of Copenhagen, Department of Cellular and Molecular Medicine) under the supervision of Professor Hans Wandall. Stay focused on the production of controlled cellular knockouts through CRISPR-Cas9 technology and FACS experiments.

Milan, Lombardy, Italy

Visiting Researcher in the laboratory of Professor Alessandra Polissi, Department of Pharmacological and Biomolecular Sciences, University of Milano. Scientific collaboration within the development of an on-cell NMR method for the rapid and precise screening of putative inhibitors of bacterial adhesin with medical implications.

Bioorg Nmr Lab

Internship for MD Thesis in Cristina Airoldi’s group (bioOrg NMR lab at University of Milano-Bicocca). Combining NMR and UPLC-HR-MS the identification of ligands of biomedical relevance and preliminary characterization of their biological activity were achieved. In particular, selected bioactive plant extracts were tested for their ability to prevent Aβ1-42 peptide aggregation and neurotoxicity in a neuronal human cell line. The detailed identification of the molecules responsible for… Show more Internship for MD Thesis in Cristina Airoldi’s group (bioOrg NMR lab at University of Milano-Bicocca). Combining NMR and UPLC-HR-MS the identification of ligands of biomedical relevance and preliminary characterization of their biological activity were achieved. In particular, selected bioactive plant extracts were tested for their ability to prevent Aβ1-42 peptide aggregation and neurotoxicity in a neuronal human cell line. The detailed identification of the molecules responsible for the anti-amyloidogenic activity was assessed by NMR. Show less

Laboratory Of Biochemistry And Nanomedicine

Placement during bachelor degree in the Laboratory of Nanomedicine, University of Milan-Bicocca in Francesca Re’s group. Research project mainly focused on the preparation of nanoparticles multi-functionalized in vitro for uptake and transport through the blood-brain barrier.

Double Phd With International Mention, Biochemistry And Molecular Biology, Sobresaliente Cum Laude

Cotutelled PhD in Synthetic and Industrial Chemistry (UPV/EHU, Bilbao) and in Converging Technologies for Biomolecular Systems (Unimib.

Master'S Degree, Industrial Biotechnology, 110 Cum Laude/110

Thesis title: "Metabolic profiling and biological characterization of natural extracts from plant Peucedanum ostruthium"

Bachelor'S Degree, Biotechnology, 108/110

Thesis title: "NMR characterization of polar metabolites extracted from post-mortem brain tissues of patients affected by Alzheimer disease"

Classical And Ancient Studies

Doctoral Program In Converging Technologies For Biomoleculars Systems (Tecsbi), Sobresaliente Cum Laude

Cotutelled PhD in Synthetic and Industrial Chemistry (UPV/EHU, Bilbao) and in Converging Technologies for Biomolecular Systems (Unimib.