Sara Gil Bernabé Email and Phone Number

Medicina genómica, predictiva y personalizada en tumores tiroideos huérfanos, agresivos y metastásicos, resistentes a radioyodo. Identificación de biomarcadores diagnósticos, pronósticos y terapéuticos.

Desde agosto de 2017 pertenezco al grupo de investigación de Patobiología del Cáncer: Heterogeneidad inter-, intra-tumoral y Dianas Moleculares del Instituto de Biología y Genética Molecular (IBGM), Centro mixto Universidad de Valladolid - Consejo Superior de Investigaciones Científicas. Donde actualmente realizo mi TFM del Máster de Investigación Biomédica. Current projects are focused in: - The study dynamic changes in mutational load distribution (clonal diversity) that occur through space and time.- The identification of new molecular mechanisms governing, at the cellular level, the transformation of indolent, morphological indistinguishable differentiated Papillary Thyroid Carcinomas or minimally invasive differentiated Follicular Thyroid Carcinomas into highly aggressive Poorly Differentiated Thyroid Carcinomas or Undifferentiated / Anaplastic Thyroid Carcinomas- The identification and characterization of new signalling pathways and molecules involved in thyroid follicular cell neoplastic transformation, which exert a pivotal role in tumor maintenance, tumor progression (appearance of recurrences, cell migration, acquisition of metastatic properties, epithelial- mesenchymal transition, stemness perpetuation) and intrinsic or acquired resistance to conventional therapies or targeted drugs.- The identification of interactions / cross-talks between activated effectors of the RAS/BRAF/ERK pathway, the PI3K/AKT pathway, the Wnt pathway or the activated TERT promoter and other unknown molecules, which may exert a key role in the partial, self-limited response observed so far to kinase inhibitors and other targeted drugs given to patients with advanced, metastatic, radioiodine resistant papillary thyroid carcinomas, poorly differentiated thyroid carcinomas and undifferentiated / anaplastic thyroid carcinomas

Visiting PhD Student at Landa Lab in Harvard Medical School and Brigham and Women’s Hospital

Prácticas de Gestión de Proyectos de I+D+i

Realicé mis prácticas curriculares en el departamento de Análisis clínicos del Hospital Universitario Río Hortega. Conocimientos en las áreas de recepción de muestras, bioquímica, serología, fluidos biológicos, inmunología y genética clínica.