Sara Klose Email & Phone Number

Bornheim, North Rhine-Westphalia, Germany

In my role as a Research and Development Project Manager for AST/ART at MERLIN, a Bruker company, I am managing projects focused on Antimicrobial Susceptibility and Resistance Testing products, which are crucial for the phenotypic detection of anmicrobial resistance. My role involves development and optimisation of these diagnostics, with the ultimate goal of improving the health of both humans and animals.

Bonn, North Rhine-Westphalia, Germany

- Co-leading working package 1 of the MyMIC project, a global industry funded project comprised of international academic institutions and diagnostic laboratories to standardise the antimicrobial susceptibility testing of animal mycoplasmas- Co-leading an Australian industry funded project investigating coinfection dynamics between viral and bacterial pathogens of cats, and drafting 3 manuscripts from this work for peer-reviewed publications - Collaborating on a government… Show more - Co-leading working package 1 of the MyMIC project, a global industry funded project comprised of international academic institutions and diagnostic laboratories to standardise the antimicrobial susceptibility testing of animal mycoplasmas- Co-leading an Australian industry funded project investigating coinfection dynamics between viral and bacterial pathogens of cats, and drafting 3 manuscripts from this work for peer-reviewed publications - Collaborating on a government funded project to improve vaccine efficacy against mycoplasmas using the CRISPR system developed in own earlier work - Acting on the Scientific Program Committee of the 24th Congress of the International Organisation for Mycoplasmology (IOM) to be held in Osaka, Japan, in July 2023- Co-supervising a PhD project in functional genomic and metabolomic studies of mycoplasmas Show less

Werribee, Victoria, Australia

- Initiated and managed parallel projects, from logistics and budget management to execution and problem solving. Prepared progress reports, and delivered on milestones outlined by funding bodies - Managed large poultry clinical trials, from initial ethics applications and experimental design to translational application of the research outcomes, including logistics, budget management, delegation of tasks with collaborators, and coordination of a team of scientists assisting in the… Show more - Initiated and managed parallel projects, from logistics and budget management to execution and problem solving. Prepared progress reports, and delivered on milestones outlined by funding bodies - Managed large poultry clinical trials, from initial ethics applications and experimental design to translational application of the research outcomes, including logistics, budget management, delegation of tasks with collaborators, and coordination of a team of scientists assisting in the trials- Led the collection of samples from prominent mycoplasma diagnostic laboratories in Europe resulting in development of an archive of more than 100 live MS-H vaccine isolates obtained from poultry farms enabling further comprehensive studies of vaccine behaviour- Utilised genomic and metabolomic approaches to investigate the stability of the live bacterial MS-H vaccine resulting in insight into the behaviour of this vaccine in poultry farms- Organised and chaired several steering committee meetings on project outcomes with industry partner, Bioproperties Pty Ltd, which consistently received positive feedback- Implemented systems to ensure a well-run laboratory compliant with Australian Gene Technology regulations and Occupational Health and Safety requirements- Staff responsibility for one laboratory technician including funds acquisition, budget management, hiring, training, and supervision- Trained industry partner staff in metabolomics methods to enhance vaccine production- Published and submitted 4 peer-reviewed publications in journals with impact factors above the top decile in veterinary microbiology field- Promoted to Research Fellow Grade 2 (Level B) in 2022 Show less

Werribee, Victoria, Australia

- Presented lectures in Veterinary Public Health for Doctor of Veterinary Medicine postgraduate students- Presented lectures in Animal Disease Biotechnology for Bachelor of Science students

Parkville, Victoria, Australia

- Contributed to New Zealand’s Mycoplasma bovis eradication programme by investigating effective disinfectants against this cattle pathogen, and providing strategies to improve national disinfection protocols- Drafted progress reports and managed project progress according to endorsed timelines by New Zealand Ministry for Primary Industries, and published 1 peer-reviewed publications in a journal with impact factor above the top decile in veterinary microbiology field- Led the… Show more - Contributed to New Zealand’s Mycoplasma bovis eradication programme by investigating effective disinfectants against this cattle pathogen, and providing strategies to improve national disinfection protocols- Drafted progress reports and managed project progress according to endorsed timelines by New Zealand Ministry for Primary Industries, and published 1 peer-reviewed publications in a journal with impact factor above the top decile in veterinary microbiology field- Led the organising committee of the Asia-Pacific Centre for Animal Health Symposium to demonstrate the research portfolio of the centre over the past 20 years with more than 100 attendees- Accomplished the best logo design among 10 participants, resulting in an updated official logo for the Asia-Pacific Centre for Animal Health, University of Melbourne Show less

Parkville, Victoria, Australia

- Developed the endogenous CRISPR system of mycoplasmas as a genome engineering tool- Established the first targeted knock-out and knock-down method available for mycoplasmas attracting interest from some of the most prominent international mycoplasmologists- Utilised metabolomics to study the gene function of mycoplasmas- Published 3 peer-reviewed publications in journals with impact factors above the top decile in veterinary microbiology field

Parkville, Victoria, Australia

- Trained Doctor of Veterinary Medicine postgraduate students in routine laboratory techniques in Veterinary Microbiology, Microbiology in Agriculture, and Veterinary Virology subjects- Demonstrated practical workshops in Animal Production Systems and Production Animal Health subjects

Bonn, North Rhine-Westphalia, Germany

- Managed a European funded project to improve knowledge on pathophysiology of Age-related Macular Degeneration (AMD) and identify novel diagnostic biomarkers and therapeutic approaches.- Facilitated national and international collaborations to conduct comprehensive assessments of the microbiome, metabolome, cytokine, and complement activation levels throughout the disease progression, as well as coordinating sample shipments.- Supervised technical assistants to organise the… Show more - Managed a European funded project to improve knowledge on pathophysiology of Age-related Macular Degeneration (AMD) and identify novel diagnostic biomarkers and therapeutic approaches.- Facilitated national and international collaborations to conduct comprehensive assessments of the microbiome, metabolome, cytokine, and complement activation levels throughout the disease progression, as well as coordinating sample shipments.- Supervised technical assistants to organise the laboratory based on regulations and ensure compliance.- Managed the advertisement of staff and student positions, as well as conducting selection processes for new staff interviews including organising interviews, coordinating the prospective staff’s visits, and assessing their suitability to join the laboratory.- Developed and managed budgets for research projects, forecasting expenses, monitoring spending, and ensuring financial accountability in alignment with project objectives and funding constraints.- Selected and organised lab rotation opportunities for master's students, allocating time and staff resources accordingly.- Organised regular lab meetings to facilitate collaborative discussions, knowledge sharing, and effective communication among team members.- Conducted comprehensive assessments of the microbiome composition's correlation with AMD.- Evaluated cytokine profiles and complement activation levels throughout the progression of AMD.- Established microglial cell cultures and to serve as a reliable and consistent model for conducting phagocytosis assays. Show less

Bonn, North Rhine-Westphalia, Germany

- Contributed to the preparation of a review paper focusing on the role of cytokines in pathophysiology of AMD.

- Supervised and assessed safety and quality of meat products resulting in a reduced burden of foodborne diseases and thus, an improved public health- Expanded engagement with the industry stakeholder- Facilitated and managed the consultation process between personnel and management

Melbourne Teaching Certificate, Higher Education/Higher Education Administration

Doctor Of Philosophy (Ph.D.), Veterinary Microbiology

Doctor Of Veterinary Medicine (Dvm), Veterinary Medicine

Activities and Societies: Veterinary Science