• Managed research focused on targeted anticancer therapy and cancer multidrug resistance, successfully Identified small molecules for on potential cancer targets as PLK1, TCTP, and Aurora kinase. Leveraged advanced in vitro molecular biology methodologies and pharmacogenomic investigations to comprehensively evaluate target mechanisms.• Spearheaded a comprehensive study utilizing in vitro and in silico methodologies to identify potential compounds with inhibitory properties against the main protease (Mpro), methyltransferase and nucleocapsid of coronaviruses.• Led projects and in SARS-CoV-2 drug discovery by developing and applying pseudotyping techniques to optimize neutralization assays targeting the Spike protein, and enabling more effective assessment of potential small molecule drugs.• Conducted groundbreaking research utilizing a highly sensitive transcriptomic approach to assess the impact of low concentrations of Pyrrolizidine alkaloids (PAs) on human cytochrome P450 3A4-overexpressing HepG2 clone 9 hepatocytes, revealing disruption of key signaling pathways related to cell cycle regulation and DNA damage repair, providing insights into the potential carcinogenic effects of PAs.• Collaborated with the informatics department, developed a robust workflow for structure-based virtual ligand screening, ensuring accurate target-drug interaction investigations and potential hit candidate identification. Utilized a structure-based approach and incorporated comprehensive features for effective virtual screening, including the option for re-screening promising ligands across related target proteins, enhancing scientific reproducibility and efficiency.• Supervised and mentored master and PhD students• Developed and delivered lectures on molecular biology of cancer for undergraduate pharmacy students.• Published 30 research articles in internationally well-reputed journals

Lead Discovery of Anticancer Molecules acting as Polo-like Kinase inhibitors ‘’ This project we applied high throughput screening methods with in-silico molecular docking to identify hit candidates. Advanced molecular techniques were used to validate the in-vitro mode of action of molecules that bind selectively to the PLK1 enzyme.

• Developed and delivered engaging lab protocols and assignments for courses like Physical Pharmacy, Pharmaceutical Calculations, and Pharmacokinetics.• Cultivated a dynamic learning environment in labs through effective activity management, hands-on guidance, and meticulous evaluation, ensuring quality and student success.• Taught pharmacy students essential pharmacokinetic and bioavailability skills, preparing them to evaluate clinical effectiveness and ensure optimal drug treatment efficacy.

• Act as primary contact to the Sudan local Health Authority for assigned products and ensure professional and trustful communication. • Registration of drug items; Ensure local regulatory compliance by properly documented submission of registration dossiers.• Contribute to the preparation of answers to deficiency letters and other authority requests in cooperation with global Regulatory Affairs