Sara Abdelfatah Email & Phone Number

Seattle, WA, US

Mainz, Germany

• Managed research focused on targeted anticancer therapy and cancer multidrug resistance, successfully Identified small molecules for on potential cancer targets as PLK1, TCTP, and Aurora kinase. Leveraged advanced in.
• Spearheaded a comprehensive study utilizing in vitro and in silico methodologies to identify potential compounds with inhibitory properties against the main protease (Mpro), methyltransferase and nucleocapsid of.
• Led projects and in SARS-CoV-2 drug discovery by developing and applying pseudotyping techniques to optimize neutralization assays targeting the Spike protein, and enabling more effective assessment of potential small.
• Conducted groundbreaking research utilizing a highly sensitive transcriptomic approach to assess the impact of low concentrations of Pyrrolizidine alkaloids (PAs) on human cytochrome P450 3A4-overexpressing HepG2 clone.
• Collaborated with the informatics department, developed a robust workflow for structure-based virtual ligand screening, ensuring accurate target-drug interaction investigations and potential hit candidate.
• Supervised and mentored master and PhD students

Mainz Area, Germany

Lead Discovery of Anticancer Molecules acting as Polo-like Kinase inhibitors ‘’ This project we applied high throughput screening methods with in-silico molecular docking to identify hit candidates. Advanced molecular techniques were used to validate the in-vitro mode of action of molecules that bind selectively to the PLK1 enzyme.

Sudan

• Developed and delivered engaging lab protocols and assignments for courses like Physical Pharmacy, Pharmaceutical Calculations, and Pharmacokinetics.
• Cultivated a dynamic learning environment in labs through effective activity management, hands-on guidance, and meticulous evaluation, ensuring quality and student success.
• Taught pharmacy students essential pharmacokinetic and bioavailability skills, preparing them to evaluate clinical effectiveness and ensure optimal drug treatment efficacy.

Sudan

• Act as primary contact to the Sudan local Health Authority for assigned products and ensure professional and trustful communication.
• Registration of drug items; Ensure local regulatory compliance by properly documented submission of registration dossiers.
• Contribute to the preparation of answers to deficiency letters and other authority requests in cooperation with global Regulatory Affairs

Master'S Degree, Regulatory Affairs

Doctor Of Pharmacy - Pharmd, Summa Cum Laude (Excellent)

Master'S Degree, Molecular Medicine

Bachelor'S Degree, Pharmacy, B.A. Of Pharmacy Honours Degree Second Class Division 1