Sarah Griner, Phd

Sarah Griner, Phd Email and Phone Number

Research Scientist at ADRx, Inc. @ ADRx, Inc.
Sarah Griner, Phd's Location
Los Angeles, California, United States, United States
Sarah Griner, Phd's Contact Details

Sarah Griner, Phd work email

Sarah Griner, Phd personal email

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About Sarah Griner, Phd

I am a research scientist working to understand the molecular mechanisms of disease in order to rationally design therapeutics. My expertise spans all stages of the research process: project design, experimental implementation, data analysis and interpretation, and communicating results. Specific fields of interest include neurodegenerative diseases, auto-immune diseases, antibody therapeutics, and peptide-based pharmaceuticals.Areas of significant contribution include:- Expression, purification, biophysical characterization, and structure determination of protein targets- Inhibitor validation using a wide array of biochemical and in vitro assays- Formation of Antibody complexes for structural characterization

Sarah Griner, Phd's Current Company Details
ADRx, Inc.

Adrx, Inc.

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Research Scientist at ADRx, Inc.
Sarah Griner, Phd Work Experience Details
  • Adrx, Inc.
    Research Scientist Ii
    Adrx, Inc. Jan 2022 - Present
    Thousand Oaks, California, Us
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  • Adrx, Inc.
    Research Scientist
    Adrx, Inc. Apr 2021 - Jan 2022
    Thousand Oaks, California, Us
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  • University Of California, Los Angeles
    Postdoctoral Researcher
    University Of California, Los Angeles Apr 2019 - Apr 2021
    Los Angeles, Ca, Us
    -isolated Amyloid Beta species from patient tissue-purified and characterized stable Amyloid Beta oligomers-formed Amyloid Beta and antibody/nanobody/Fab complexes for structural studies-purified COVID-19 Nucleocapsid protein constructs-mentored graduate students
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  • University Of California, Los Angeles
    Gradute Student
    University Of California, Los Angeles Sep 2011 - Apr 2019
    Los Angeles, Ca, Us
    -Engineered and purified full length Amyloid Beta constructs from recombinant expression, synthesized peptides-Crystallized and solved structures of Amyloid Beta peptides using X-Ray and Micro-Electron Diffraction data collection-Characterized amyloid aggregation by Thioflavin T (ThT) aggregation assay and electron microscopy-Designed peptide inhibitors of Amyloid Beta aggregation and characterized efficacy using cell-based toxicity assays and negative stain EM-Determined potential interfaces on Amyloid Beta allowing cross-amyloid seeding of aggregation with Tau (Alzheimer's Disease) and IAPP (Type 2 diabetes)
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  • University Of California, San Francisco
    Staff Reseach Assoc. Iii
    University Of California, San Francisco Nov 2005 - Jul 2011
    San Francisco, California, Us
    -Engineered tethering sites on HIV-I Integrase to complex with DNA to enable drug design-Protein expression and purification of proposed Human Pre-Integration complex proteins - Protein interaction testing of Human Pre-Integration complex proteins with Integrase-Crystallized and assayed activity of RNA modifying enzymes. -Successfully expressed and purified Fabs, and crystallized with target protein-Responsible for supply ordering and basic equipment maintenance
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Sarah Griner, Phd Skills

Molecular Cloning Pcr Protein Purification Protein Expression

Sarah Griner, Phd Education Details

  • Ucla
    Ucla
    Biochemistry And Molecular Biology
  • Reed College
    Reed College
    Chemistry

Frequently Asked Questions about Sarah Griner, Phd

What company does Sarah Griner, Phd work for?

Sarah Griner, Phd works for Adrx, Inc.

What is Sarah Griner, Phd's role at the current company?

Sarah Griner, Phd's current role is Research Scientist at ADRx, Inc..

What is Sarah Griner, Phd's email address?

Sarah Griner, Phd's email address is sg****@****cla.edu

What is Sarah Griner, Phd's direct phone number?

Sarah Griner, Phd's direct phone number is +150351*****

What schools did Sarah Griner, Phd attend?

Sarah Griner, Phd attended Ucla, Reed College.

What skills is Sarah Griner, Phd known for?

Sarah Griner, Phd has skills like Molecular Cloning, Pcr, Protein Purification, Protein Expression.

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