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My professional journey across bench science, clinical medicine, and regulatory science at FDA, has provided a uniquely broad background in drug development. As a clinical fellow and then an investigator and attending physician at NIH, I developed a program at the intersection of infectious diseases, autoimmunity, and oncology. I became a leading international authority in diagnosing and managing patients with acquired, genetic, and malignancy-associated immunodeficiencies related to endogenous production of high-titer, neutralizing anticytokine autoantibodies. Subsequently, I brought my scientific and clinical experience to the FDA, first as a clinical reviewer, then progressing quickly in management as Senior Advisor for Clinical Review and Office Lead for Biomarkers. In 2020, I joined Altimmune and have been clinical development lead for all programs in obesity, metabolic, and liver disease. While at Altimmune, I have built a diverse team encompassing clinical development, pharmacovigilance, medical affairs, and medical monitoring to advance programs from First-in-Human through Phase 2. I have established multiple scientific advisory boards, managing internationally recognized experts across the fields of obesity, cardiometabolic, hepatology, renal, and body composition. I strive to bring vision and pragmatism to execute evidence-based, creative, and ambitious clinical development programs through hands-on engagement, team-building, and cross-disciplinary collaboration.
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Vice President Clinical DevelopmentAltimmune, Inc. Jan 2023 - PresentGaithersburg, Maryland, Us -
Senior Director, Clinical DevelopmentAltimmune, Inc. Oct 2020 - Mar 2023Gaithersburg, Maryland, Us -
Senior Director, Clinical DevelopmentAltimmune, Inc. Jul 2021 - Feb 2023Gaithersburg, Maryland, Us -
Senior Advisor-ClinicalFda Oct 2018 - Oct 2020Silver Spring, Md, UsSenior Management for Division of Vaccines and Related Product Applications (DVRPA) for Office of Vaccines Research and Review (OVRR), Center for Biologics Evaluation and Research (CBER), US FDA-Functional role was deputy division director for clinical review; promoted from medical officer (see below) to manage the toxicology branch and the two clinical branches (each comprised of about 13 medical offers, 2 team leads and led by a branch chief).-Oversee clinical review activities along with other division leadership-OVRR lead on biomarkers for use as drug development tools and regulatory decision-making-Lead for medical officer recruitment, hiring, and professional development -
Medical OfficerFda Aug 2014 - Oct 2018Silver Spring, Md, UsClinical Reviewer for DVRPA/OVRR/CBER/FDA-Subject matter expert for clinical review, preventive vaccines, live biotherapeutic products, bacteriophage, and human challenge models-Clinical reviewer for 2 original BLAs, 3 efficacy supplements, over 65 INDs, and type V master files -FDA speaker at 2 advisory committee meetings-Organizing committee for multiple advisory committee meetings including 2017 VRBPAC discussing development of vaccines to prevent RSV in RSV-naïve children (see Browne et al, Vaccine, 2019, publication # 1 on attached CV) -
Assistant Clinical InvestigatorNational Institutes Of Health Jul 2010 - Aug 2014Bethesda, Md, UsTranslations scientist and infectious diseases attending-Principal investigator on 1 clinical trials and one natural history protocol and co-investigators on multiple clinical studies -Ran laboratory based translational research program diagnosing (see Ding et al., Browne senior author, J of CI, 2011, publication #32 on attached CV) and treating (see Browne et al, Blood, 2012 publication #29 on attached CV) and consulting (nationally and internationally) on patients with anti-cytokine autoantibody-associated immunodeficiencies (see Browne et al. NEJM, 2012, Rosen et al., Browne senior author, J Immunol 2012, and Rosen et al., Browne senior author, CID, 2015 on attached CV, publications # 30, 28, and 16, respectively)-Attending on infectious diseases consult service at NIH Clinical Center-Served as lab mentor to individuals ranging from high-school students to post-doctoral fellows
Sarah Browne Skills
Sarah Browne Education Details
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Virginia Commonwealth University School Of MedicineMedicine -
Williams CollegeBiology -
Brigham And Women'S Hospital And Harvard Medical SchoolInternal Medicine Residency Program -
National Institutes Of Allergy And Infectious DiseasesInfectious Diseases Fellowship Program
Frequently Asked Questions about Sarah Browne
What company does Sarah Browne work for?
Sarah Browne works for Altimmune, Inc.
What is Sarah Browne's role at the current company?
Sarah Browne's current role is Vice President, Clinical Development.
What is Sarah Browne's email address?
Sarah Browne's email address is sa****@****ail.com
What is Sarah Browne's direct phone number?
Sarah Browne's direct phone number is +130179*****
What schools did Sarah Browne attend?
Sarah Browne attended Virginia Commonwealth University School Of Medicine, Williams College, Brigham And Women's Hospital And Harvard Medical School, National Institutes Of Allergy And Infectious Diseases.
What skills is Sarah Browne known for?
Sarah Browne has skills like Infectious Diseases, Translational Research, Clinical Research, Internal Medicine, Medicine.
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