Sara O'Brien Email & Phone Number

Cambridge, Massachusetts, United States

• Assist senior-level staff in designing statistical analysis plans and table/figure/listing (TFL) shells in accordance with study protocols• Assist in developing SAS programs to produce and/or QC analysis datasets and statistical tables/figures/data listings according to analysis data specifications and TFL shells• Assist senior-level staff in performing stat review of analysis datasets and tables/figures/data listings• Assist in developing SAS programs to produce randomization schedules• Review electronic case report form specifications and data validation guidelines to ensure quality and integrity of study data collection

Boston, Ma

• Run local and tissue-specific heritability analyses to capture genetic architecture of sleep apnea • Leverage Python/R, bash scripting, and genetic association/correlation software programs (PLINK, LDAK, LAVA, regenie) to navigate TOPMed and biobank data

Chapel Hill, North Carolina, United States

• Analyze the associations between various -omics measures, psychosocial stressors, and cardiovascular disease outcomes in the JHS through regression and causal mediation models in R• Prepare and contribute to conference presentations, manuscripts, and Honors Thesis to disseminate findingsLab website: https://www.med.unc.edu/genetics/raffieldlab/

Durham, North Carolina, United States

• Run descriptive statistics in R to better characterize the quantity and quality of biospecimens in Target’s biorepository• Link biospecimen data to clinical outcomes and treatment events to improve marketability of biorepository (a top 4 company priority for 2023 Q4)• Push data to Target’s proprietary SaaS tool, CausalStudio, to create interactive visualizations (cumulative incidence curves, sankey diagrams, charts and figures) for internal and external use• Assist in preparing manuscripts for publication

Chapel Hill, North Carolina, United States

• Draft and reference statistical computing requests and create quality control programs in SAS for data monitoring and management of the JHS Dementia study at the Collaborative Studies Coordinating Center• Write data dictionaries to catalog newly derived variables and run weekly reports to track the status of data queries in the ARIC ACHIEVE study

• Review automated data queries to provide feedback to ML model and address discrepancies in CRFs• Maintain accurate records through QC of study start-up documentation• Pull study metrics into weekly summary reports for study team

Chapel Hill, North Carolina, United States

• Conduct data cleaning, coding, analysis, and visualization in Atlas.ti• Develop regulatory and support documents (workflow visualizations, SOPs, summary sheets, meeting minutes, etc.)• Design surveys and perform data entry and cleaning in REDCap and Qualtrics• Screen articles and extract data for a systematic review

Rocky Mount, North Carolina, United States

• Developed an 8-week professional development curriculum for mappers• Conducted field checks, data cleaning, and quality assurance on asset database

Chapel Hill, Nc

Master Of Science - Ms, Biostatistics

Activities and Societies: Admissions Ambassador, FirstGen MentorEmma Gildersleeve Lane Scholarship Recipient

Bachelor Of Science In Public Health - Bsph, Biostatistics

Graduated with Highest Honors and Highest Distinction

Bachelor Of Arts - Ba, Hispanic Literatures And Cultures

Activities and Societies: Honors Carolina (2019-2023), Public Health 360 Co-President (2021-2023), Carolina Firsts Scholar (2019-2023).