Sara Silacci is a social entrepreneur with over 25 years of experience driving mission-oriented strategic growth initiatives. Passionate about creating sustainable programs and profitable businesses that enable healthcare transformation, she founded Mission4Margin in 2023 to achieve this vision. Sara collaborates with a diverse portfolio of clients across both the private and public sectors, offering guidance on strategic investments to diversify revenue, expand impact, and forge a lasting future through entrepreneurship, innovation, and sound business strategy.Formerly the Chief Strategy Officer for Research and Innovation at Massachusetts General Hospital and a founding member of Mass General Brigham, Sara played a pivotal role in advancing the largest hospital system-based research enterprise in the U.S., with an annual budget exceeding $2.3 billion.Sara's journey is defined by innovation, collaboration, and transformative leadership, making a profound impact on the healthcare landscape. She operationalized intricate public-private partnerships, investments, and transactions to expedite the development and commercialization of groundbreaking therapeutics and technologies. Her dynamic approach has created several self-sustaining and revenue-generating programs and ventures that set new standards in healthcare innovation. Notably, during her nine-year tenure as Senior Managing Director of Development for the Mass General Cancer Center, she achieved a 15X increase in annual philanthropic and sponsored research support.Sara also played a pivotal role as the Director of Development for National and International Growth Campaigns at Boston Children’s Hospital, where she spearheaded strategic initiatives in collaboration with the Board of Trustees and hospital leadership to establish a presence in key national and international markets. She began her career at Memorial Sloan Kettering Cancer Center, gaining experience in research operations, public affairs, and corporate relations.Sara's pioneering work in healthcare has garnered several prestigious awards, including the Partners Healthcare H. Richard Nesson Award for Excellence in Patient Safety and Innovation. Recognized as one of Boston Business Journal’s Top 40 Under 40, Sara continues to make substantial contributions to the field.As a co-author of numerous peer-reviewed healthcare publications spanning digital health, telemedicine, Electronic Health Records (EHRs), and COVID-19, Sara consistently demonstrates her unwavering commitment to advancing critical healthcare discourse.