Sasheen Hamilton, Ph.D., M.A. Email & Phone Number

Rockville, Maryland, United States

Rockville, Maryland, United States

- Led over 12 products through the design control and quality standard processes for release to the market.- Execute multiple project planning and writing of product design documentations. Technical lead of CAPA Documents and Material Review Board (MRB) meetings. - Schedule experiments, conduct analysis and critical review of data while trouble-shooting and optimizing experiments; communicate issues and solutions to senior management team- Manage and coordinate the activities of… Show more - Led over 12 products through the design control and quality standard processes for release to the market.- Execute multiple project planning and writing of product design documentations. Technical lead of CAPA Documents and Material Review Board (MRB) meetings. - Schedule experiments, conduct analysis and critical review of data while trouble-shooting and optimizing experiments; communicate issues and solutions to senior management team- Manage and coordinate the activities of over 15 Research Associates and Scientists, including but not limited to: training, establishing work assignments and deadlines, set priorities, and ensure compliance to document and record control. - Cross-functional collaboration with other groups, including but not limited to: Quality Assurance, Quality Control, Manufacturing, Operations, and Assay Development. Show less

Bethesda, Maryland, United States

Current research aims to develop a novel hepatocellular carcinoma targeted therapeutic agent against glypican-3 utilizing: 1) humanized monoclonal antibody (Codrituzumab, in phase II clinical trial), and 2) de novo nanobodies. - Initiate and plan experimental protocols to effectively create detailed project road maps, risk management, and milestone deadlines. - Execute hands-on experiments involving phage display library generation (TG1 cells, M13 helper phage), binding affinity assays… Show more Current research aims to develop a novel hepatocellular carcinoma targeted therapeutic agent against glypican-3 utilizing: 1) humanized monoclonal antibody (Codrituzumab, in phase II clinical trial), and 2) de novo nanobodies. - Initiate and plan experimental protocols to effectively create detailed project road maps, risk management, and milestone deadlines. - Execute hands-on experiments involving phage display library generation (TG1 cells, M13 helper phage), binding affinity assays (ELISA, biolayer interferometry), quality assurance (chromatography, gel electrophoresis), and radiotherapy animal studies (pharmacokinetics, biodistribution, and therapy). - Create analytical data reports, present key accomplishments/obstacles and strategic troubleshooting to the principal investigator, collaborators, senior management, and conferences. - Organizes and participates in lab team-building events and provides training to post-baccalaureate fellows. Show less

Buffalo/Niagara, New York Area

Ph.D. thesis defined the impact of light-induced tissue heating during the interstitial photodynamic therapy of a locally advanced squamous cell carcinoma tumor model. - Wrote a successful supplemental grant application to NCI, resulting in funding for my translational Ph.D. project for 3 years. Communication with 12 multidisciplinary team members, achieved 2 co-author peer-reviewed publications. - Organized, analyzed, and presented detailed progress reports… Show more Ph.D. thesis defined the impact of light-induced tissue heating during the interstitial photodynamic therapy of a locally advanced squamous cell carcinoma tumor model. - Wrote a successful supplemental grant application to NCI, resulting in funding for my translational Ph.D. project for 3 years. Communication with 12 multidisciplinary team members, achieved 2 co-author peer-reviewed publications. - Organized, analyzed, and presented detailed progress reports, strategic plans, and budget reviews to the principal investigator weekly, committee members (senior management) quarterly, and department seminars yearly. - Initiated a strategy for my lab's histology services following the shutdown of the core facility due to the COVID-19 pandemic. The protocol changes and collaborations led to a decrease in histology budget cost by 66% and a substantial improvement in turnaround time of < 4 days.- Supervised projects and monitored milestone deadlines with summer interns, undergraduates, and graduate students. Show less

Buffalo, New York, United States

My primary project characterized the effects of the linker domain length on DNA-single-stranded binding target protein. - Completion of my project resulted in the successful funding of a Ph.D. dissertation proposal from NIH and 2 co-author publications. - Documented and maintained files for 2 projects, including research plans, experimental results, budgets, and vendors. Consults weekly with the principal investigator and team members on project updates/setbacks, and quarterly at… Show more My primary project characterized the effects of the linker domain length on DNA-single-stranded binding target protein. - Completion of my project resulted in the successful funding of a Ph.D. dissertation proposal from NIH and 2 co-author publications. - Documented and maintained files for 2 projects, including research plans, experimental results, budgets, and vendors. Consults weekly with the principal investigator and team members on project updates/setbacks, and quarterly at department seminars. - Managed and mentored post-baccalaureate and graduate students on the elements of performing good laboratory practice. Show less

Doctor Of Philosophy - Phd, Biophysics (Biophysical Oncology)

Master Of Arts - Ma, Biochemistry

Bachelor Of Science - Bs, Biology/Biological Sciences, General

Transferred, Mathematics And Science