Scott Sauer Email & Phone Number

Boston, MA, US

Oversee and coordinate our patent portfolio as well as academic and industrial collaborations.

US

• (Laboratory of Gayathri Devi, PhD)
• Utiilized high-throughput and high content compound screening to identify environmental chemicals that increase proliferation of breast cancer cells and attenuate anticancer drug efficacy, while determining the.
• Investigated mechanisms of oxidative stress, proliferative signaling and acquired therapeutic resistance in inflammatory breast cancer (IBC) culminating in co-first author publication
• Elucidated mechanisms of resistance towards cancer immunotherapy and identification of targeting strategies to overcome this resistance, leading to second author publication
• Directly oversaw the design and execution of individual projects, as well as projects for undergraduate mentees, developed and wrote individual postdoctoral grants (5) as well as co-wrote laboratory grants with PI (15.

Durham, North Carolina, US

This is a program that seeks to increase diversity and undergraduate engagement in biomedical research. I helped coordinate the research and activities of 10-20 undergraduate researchers in various biomedical laboratories for the Duke Summer Research Opportunity Program by scheduling seminars, planning and executing social events, working as a liaison.

Durham, North Carolina, US

• Graduate Student in Organic Chemistry in the lab of Dr. Don Coltart
• Developed new methods for direct carbon—carbon bond formation through the reductive enolization of α-halothioesters in the context of the aldol and Mannich reactions, leading to first author publication in JACS and.
• Synthesized (+)-mefloquine, a potent anti-malarial drug, in enantiomerically pure form using an ACC-directed chiral auxiliary approach developed in our lab, led to second author manuscript
• Modeling CDC25 phosphatase with potential allosteric-site small molecule inhibitors using DOCK and visualizing these interactions in Chimera
• Trained in the Pharmacological Sciences Training Program, mentored high school student in organic research, taught and tutored general and organic chemistry for 6 years

Franklin Lakes, New Jersey, US

• (Under supervision of project head Stacy Holdread)
• Synthesized chemically defined cell culture media, along with various growth factors and cytokines of interest; led to identification of optimum culture conditions for contract partner to create a media formulation to.
• ICP and HPLC to evaluate the amino acid and metallic makeup of various commercial peptones
• Benchtop and bio-reactor/industrial growth of E. coli in various media; optimized pharmacological protein yield from E. coli, generating data used for BD’s presentation at the American Society for Microbiology
• Aided in the programming and validation of a robotic system for the handling, culturing and analysis of cells cultured with proprietary media formulations for an automated process that was subsequently used at BD
• Employed large-scale sterile filling for the pilot production of developmental media formulations used by contract partners

Ph.D., Organic Chemistry

B.S. Chemistry, Chemistry