Scott Harpstrite Email & Phone Number

Greater St. Louis Area

Responsibilities:- Oversee laboratory facilities- Maintain instruments and inventories- Develop SOPs- Promote laboratory compliance with established guidelines- Manage shipping and receiving

Vijay Sharma laboratory, ICCE/BRIGHT Institute, Molecular Imaging CenterResearch: The discovery and preclinical in vivo validation of novel imaging agents, including substrates of cellular transporter proteins for investigation of their functional activity, and molecules designed to target biomarkers of neurodegenerative diseasesResponsibilities and Accomplishments:- Lead researcher on multidisciplinary and collaborative projects- Oversaw tissue culture facilities- Developed and executed in vivo animal imaging projects- Evaluated preclinical compounds: in vitro, in cellulo, and in vivo- Served as Honest Broker- Established and fulfilled project milestones for data collection and presentation- 15 peer reviewed publications, 5 first author publications- Presented 6 posters at international meetings- Mentored several post-docs and over 20 graduate, undergraduate, and high school students- Managed, operated, and maintained a small-animal 3D in vivo imaging system (NanoSPECT/CT)- Established laboratory compliance with university regulatory committees (EH&S, Radiation Safety)- Served as webmaster for laboratory websites and lab liaison for department computer section

Vijay Sharma and David Piwnica-Worms laboratories, Molecular Imaging CenterResearch: The synthesis, characterization, and in vitro biochemical analysis of molecular imaging reagents, including the metal-polydentate radiotracer probes for monitoring multidrug resistance (MDR) transporters, and peptides and small organic molecules for visualization of β-amyloid plaquesResponsibilities and Accomplishments:- Oversaw and executed projects and experiments- Synthesized and characterized developmental compounds- Instrument and inventory maintenance (HPLC, FT-IR, UV/Vis)- IT experience, including proficiency in various software (Word, Excel, Photoshop, Illustrator)- Served aswebmaster for laboratory websites and lab liaison for department computer section

James R. McClure laboratoryResearch: The synthesis and characterization of substituted pyrazolesResponsibilities and Accomplishments:- Developed a multi-step synthesis for substituted pyrazoles- Presented data at lab meetings, student seminars, and institutional poster sessions- Taught laboratory classes (prepared and presented lectures, demonstrated procedures)- Tutored students

James R. McClure laboratoryResearch: The synthesis and characterization of novel drug-like heterocyclic molecules.

Ms, Chemistry

James R. McClure laboratory | Thesis: The Synthesis of 3(5)-Substituted Pyrazoles I developed a multi-step synthetic method.

Bs, Chemistry, Acs Certified

General Research: I synthesized novel organic molecules to learn various reactions and techniques, which include: alkyne coupling; use.