Sebastien Dazy, Phd Email & Phone Number

EVRY, FR

Paris, France, FR

Temporary position to support operational qualification and validation service. Upgrading qualification guide of air handling unit (AHU) and GxP cleanrooms of val-de-reuil plant. IQ, OQ of GxP equipments. software Geode, Gibraltar, pReference,...

La Plaine Saint-Denis, Île-de-France, FR

Ensuring successful cGMP manufacturing of CAR T-cell products as part of Phase I/II clinical trials established. Plan, manage and coordinate activities related to the buildout of the production site (oversight of qualification of cGMP suites, OQ, PQ, OOS, CAPA, Method Validation... ) Class A aseptic manufacturing facilities of human GMO primary T cells in.

quality and risk assesment of human injectable medicines in ampoule packagingGlass vials/Ampoule check using automated detection of particules and defects by high resolution CMOS area cameras in confocal tandem configuration combined with high voltage leak detection.Team work with respect of cGMPs, productivity and quality continuous improvement average.

manufacture of hydrogel bioreactors for 3D cellular cultures for applications -in preclinical drug screening assays for pharmaceutic companies-in agrobusiness industries to produce high-value enzymatic compounds or meat substitutes-in biodefense

Like my previous position, providing services in Grant and R&D projects management with 30 additional collaborators.follow projets (15) from multiple fields (structural chemistry, drug screening, cancer, Alzheimer, cell biology,...)improve technical efficiency of the laboratory (40% of cost reduction), write reports (national and international), follow.

follow projets (10) achieved by 30 people, improve technical efficiency of the laboratory, write reports (national and international), follow budget, prospect for additional funding (915 000 euros collected in 2010)...Field of research: providing new innovative anti-tumoral drugs based on humanized antibodies neutralizing Dependence Receptors.

Developping industrial application in regenerative medicine of a patented biomaterial made of natural sugar polymer macroscopic physical hydrogels.proof of concept development of the use of chitosan as suitable matrix for production of vascular substitutes giving rise to a new 3rd biodegradable generation.this work leads to gain knowledge in Intellectual.

Pharmacogenomics of RXRs homo and heterodimers nuclear receptors. Developping ChIP on chip to decipher complex RXR/RAR nuclear receptor transcription factor networks at a genome-­wide level.Acquisition of reporting skills at the European level, managing report, negotiating deliverables, discussing/modifying strategic plans according to new technology.

Characterization of HP1 functions by siRNA in murine erythropoiesis using in vitro differentiation of triple knock-out mES cells (CCE cell line).Acquisition of new technological skills in confocal microscopy (FISH) and living microscopy and siRNA as well as epigenetic.Management of a £50 000/year budget within a small team (4 people), transfer of knowledge.

Recipient of French Hematology Society postdoctoral grant fellowship

Paris, 13, FR

Phd, Molecular And Cell Biology

Level 1 In Animal Testing (Bachelor Of Science (French “Du”) Animal Experimentation Level 1), Special Level Allowing To Conduct Animal Testing Assays For Biologist Managers

Master (Dea) Differentiation Genetic And Immunology