Sebastian A. Brunemeier Email and Phone Number
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Sebastian A. Brunemeier personal email
Building and investing in longevity biotech ("LongBio") companies that address the molecular mechanisms of aging ("geroscience"). Bio: Sebastian A. Brunemeier is a biotech VC and company builder focused on longevity & regenerative medicine. He is Co-Founder and General Partner of Healthspan Capital, and CEO and Founder of ImmuneAGE Bio (stealth), focused on immune system rejuvenation. Over the last 5 years, he has co-founded 4 longevity biotech (“LongBio”) companies with a total equity value of >$600M. He was Co-Founder and Chief Investment Officer at Cambrian Biopharma, Founder and COO of Samsara Therapeutics, and Principal at Apollo Health Ventures (the first and largest aging-focused venture capital fund in the world with $200M AUM). Altogether, these organizations have raised ±$400M in the last 4 years. He was a Fulbright Fellow on the biology of aging, a Skaggs-Oxford Scholar at the Scripps Research Institute, and a SENS Foundation Scholar at the Buck Institute for Research on Aging. His education includes dropping out of the DPhil (PhD) program in biochemistry of aging at the University of Oxford as a Clarendon Scholar (to launch a biotech startup called Cambrian), a Master’s in Life Science Business Management and Molecular Neuroscience from the University of Amsterdam as an Amsterdam Excellence Scholar. He served as trustee of the British Society for Research on Aging, a mentor at The New York Academy of Sciences, and as an advisor or board member to: VitaDAO/Molecule.to, Equator Therapeutics, Revivo Therapeutics, and McKinsey & Company.A few of my presentations: https://www.youtube.com/playlist?list=PL1fK3UMPdqMvp_YbqK2fnPkTQBOYD2ww4
Longgame Ventures
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- longgame.vc
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- 6
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Partner And Co-FounderLonggame VenturesUnited Arab Emirates -
Ceo & FounderImmuneage Bio Jan 2022 - PresentUs, Oxford Uk & Lausanne ChDrug discovery platform for immune system rejuvenation. ImmuneAGE.bio -
FounderLongbio Institute Aug 2024 - PresentUnited StatesAdvancing the field of Longevity Biotech (LongBio). Launching soon! -
Co-Founder & General PartnerHealthspan Capital Aug 2021 - PresentSan FranciscoVenture fund focused on longevity biotech ("LongBio") & geroscience. -
AdvisorLongevity Biotech Fellowship Nov 2022 - PresentSan Francisco, California, United States -
Faculty LecturerGeneva College Of Longevity Science May 2024 - PresentGeneva, Switzerland -
Longevity Working GroupVitadao Sep 2020 - PresentSwitzerlandFinancing longevity biotech ("LongBio") and academic partnerships via a decentralized autonomous organization. https://www.vitadao.com/ -
Initiator & Committee MemberLongevity Prize Jun 2022 - PresentGlobalPrizes for novel ideas in the geroscience & LongBio fields. Supported by Foresight Institute, VitaDAO, LEAF, etc. https://www.longevityprize.com/ -
Advisory BoardAlpine Institute Jan 2022 - PresentZurich, SwitzerlandThe world's leading longevity clinic. In stealth mode -
AdvisorMolecule Ag Sep 2020 - PresentSwitzerlandA decentralized stock exchange and licensing platform for biotech intellectual property. Originators of the VitaDAO decentralized financing platform for longevity biotech. -
Board MemberRevivo Therapeutics Nov 2020 - PresentChapel Hill, North Carolina, United StatesRevivo Therapeutics is clinical-stage pharmaceutical company developing a new class of cognitive-enhancing small molecules: nomethiazoles, which act as nitric oxide donor prodrugs and GABA(A) positive allosteric modulators. This results in CREB activation, vasodilation, reduced neuroinflammation, and reduced excitotoxicity. This MoA is neuroprotective in many animal models of CNS disease and cognitive decline. Revivo has been funded by the NIH, ADDF, and private venture capital, and we are… Show more Revivo Therapeutics is clinical-stage pharmaceutical company developing a new class of cognitive-enhancing small molecules: nomethiazoles, which act as nitric oxide donor prodrugs and GABA(A) positive allosteric modulators. This results in CREB activation, vasodilation, reduced neuroinflammation, and reduced excitotoxicity. This MoA is neuroprotective in many animal models of CNS disease and cognitive decline. Revivo has been funded by the NIH, ADDF, and private venture capital, and we are raising capital for our clinical trials now Show less -
Advisory Board & InvestorEquator Therapeutics Dec 2020 - PresentSan FranciscoDeveloping safe mitochondrial uncoupling drugs for metabolic health and longevity. A spinout of UCSF and Y Combinator. Key paper: Bertholet & Kirichok 2019 in Nature. -
AdvisorSamsara Therapeutics Jan 2020 - Present -
Founder & CooSamsara Therapeutics Jan 2018 - Jan 2020Oxford, United KingdomSamsara Therapeutics, Inc. is biopharmaceutical platform company aiming to discover first-in-class therapeutics that extend healthy lifespan. Samsara's platform is the largest ever pipeline for the identification, chemical optimization, and in vivo validation of compounds that extend healthy lifespan and enhance autophagy. Samsara Therapeutics is a global virtual biotech company with operations in Oxford, Paris, and Graz, Austria. Voted the #1 biotech startup at the FT Global Pharmaceuticals… Show more Samsara Therapeutics, Inc. is biopharmaceutical platform company aiming to discover first-in-class therapeutics that extend healthy lifespan. Samsara's platform is the largest ever pipeline for the identification, chemical optimization, and in vivo validation of compounds that extend healthy lifespan and enhance autophagy. Samsara Therapeutics is a global virtual biotech company with operations in Oxford, Paris, and Graz, Austria. Voted the #1 biotech startup at the FT Global Pharmaceuticals and Biotech conference 2019 in London. Seed financing led by Apollo Ventures with participation by Cambrian Biopharma, Qatalyst Partners, and Kite Ventures. 25M raised to date. https://www.samsaratherapeutics.com/ Show less -
Venture ScoutPicus Capital Dec 2021 - PresentInvesting in biotech and health tech. Feel free to send me your pitch deck :-) https://www.picuscap.com/ -
Odlb -- Advisor & Founding Fellow - Longevity Biotech FellowshipOn Deck Jul 2021 - Apr 2023Helping build a community of biotech founders in the 'LongBio' sector. Launched by Nathan Cheng (See: longevitylist.com). https://beondeck.com/longevity-biotech -
AdvisorMckinsey & Company Oct 2019 - Jan 2021GlobalAdvising the pharma practice (PMP) and McKinsey Global Institute. -
Cio & Co-FounderCambrian Biopharma Sep 2019 - Sep 2020New York CityCambrian Biopharma is a biotech venture capital holding company that helps scientists transmit their discoveries from the lab into the clinic. Cambrian has raised ±$150M since founding, with >10 subsidiaries. Cambrian is uniquely focused on a specific field of biomedical research: the biology of aging, also known as geroscience. Cambrian is built on an emerging business model that we call a ‘Distributed R&D Company’ or ‘DisCo’ that blends the best aspects of the venture capital firm with the… Show more Cambrian Biopharma is a biotech venture capital holding company that helps scientists transmit their discoveries from the lab into the clinic. Cambrian has raised ±$150M since founding, with >10 subsidiaries. Cambrian is uniquely focused on a specific field of biomedical research: the biology of aging, also known as geroscience. Cambrian is built on an emerging business model that we call a ‘Distributed R&D Company’ or ‘DisCo’ that blends the best aspects of the venture capital firm with the capital efficient, agile domain expertise of a mid-sized biotech company. We partner with academic geroscientists to build companies, manage preclinical drug discovery, and finance clinical trials. We have launched 10 companies with leading geroscientists globally. Founded in 2019, Cambrian is a team of over 20 scientist-entrepreneurs, venture capitalists, pharma veterans, and drug hunters located in across the US and Europe. Show less -
Ceo & Co-FounderCyclone Therapeutics 2019 - 2020La Jolla (San Diego)"Black belt chemistry" on natural products targeting the biology of aging and proteostasis. Currently in stealth mode. A spinout of The Scripps Research Institute. A portfolio company of Cambrian Biopharma. -
PrincipalApollo Health Ventures Jan 2018 - Dec 2019Hamburg Area, GermanyApollo Ventures is a life science venture capital firm and company builder working across Europe and North America, with >$200M in funds raised across two transatlantic funds. Apollo is unique among venture funds due to its focus on a specific field of scientific research – the biology of aging.apollo.vc -
AssociateDeep Knowledge Ventures Jul 2016 - Dec 2017London, United KingdomDeep Knowledge Ventures (DKV) is a London and Hong Kong-based venture firm focused on disruptive technology. Deep Knowledge Life Sciences (DKLS) is a London-based DKV subsidiary focused on biotechnology and regenerative medicine. The firm is now known as Longevity.Capital. -
Fulbright Research FellowU.S. Department Of State Sep 2014 - Aug 2015Lisbon, PortugalFulbright fellowship to conduct research on the genetics of aging -- cellular senescence, telomere dynamics, and genomic instability at the Instituto Gulbenkian de Ciencia (IGC) in the laboratory of Dr. Miguel Godinho Ferreira (HHMI investigator). -
Lab ManagerPascal Chemistry Feb 2014 - Sep 2014Irvine, CaAs an early employee, I wore several hats. I left for a Fulbright fellowship. -
Research AssistantCaltech Sep 2013 - Feb 2014Pasadena, CaBiotechnology venture capital economics research, including research on the dynamics of venture-backed IPOs. Left to help launch Pascal Chemistry. -
Sens Research Foundation ScholarBuck Institute For Research On Aging Jun 2012 - Sep 2012Novato, CaProject on neuropeptides and aging in C. elegans. Funded by the SENS Research Foundation. -
Thesis ResearchIcahn School Of Medicine At Mount Sinai Jun 2011 - Aug 2011New York CityIn the lab of Dr. John H. Morrison, Dean of the Graduate School of Biomedical Sciences and Professor of Neuroscience. Excitatory glutamatergic AMPA receptors are the most common membrane-bound receptor in the central nervous system. They and the NMDA receptors are central to long-term potentiation, memory, and mechanisms of neurodegeneration. The AMPA receptor is an obligate heterotetramer, composed of subunits GluA1-4. Subunit permutation determines ion conductance and other functional… Show more In the lab of Dr. John H. Morrison, Dean of the Graduate School of Biomedical Sciences and Professor of Neuroscience. Excitatory glutamatergic AMPA receptors are the most common membrane-bound receptor in the central nervous system. They and the NMDA receptors are central to long-term potentiation, memory, and mechanisms of neurodegeneration. The AMPA receptor is an obligate heterotetramer, composed of subunits GluA1-4. Subunit permutation determines ion conductance and other functional characteristics. Current antibodies are not subunit-specific, inhibiting the ability of researchers to accurately visualize all AMPA receptors in the nervous system. This study sought to visualize a novel monoclonal GluA1/2/3 antibody with functional avidity for three of four receptor subunits and to characterize its localization using confocal and electron microscopy. Show less
Sebastian A. Brunemeier Education Details
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Biochemistry Of Aging. Clarendon Scholarship -
Dept Of Molecular Medicine -
Cum Laude -
Cum Laude (Top 10%) -
3.85/4.00 (Magna Cum Laude, Full Scholarship) -
Telomere Biology & Cellular Senescence -
Honors Undergrad Thesis
Frequently Asked Questions about Sebastian A. Brunemeier
What company does Sebastian A. Brunemeier work for?
Sebastian A. Brunemeier works for Longgame Ventures
What is Sebastian A. Brunemeier's role at the current company?
Sebastian A. Brunemeier's current role is Partner and Co-Founder.
What is Sebastian A. Brunemeier's email address?
Sebastian A. Brunemeier's email address is se****@****game.vc
What schools did Sebastian A. Brunemeier attend?
Sebastian A. Brunemeier attended University Of Oxford, The Scripps Research Institute, University Of Amsterdam, Vrije Universiteit Amsterdam (Vu Amsterdam), Pitzer College, Gulbenkian Institute (Instituto Gulbenkian De Ciencia - Igc), Icahn School Of Medicine At Mount Sinai.
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