Seng Lor Saelee Email & Phone Number

Pleasanton, California, United States

• Collaborate with team leads to develop and optimize protocols to investigate the role of higher-order genome structures, including methylation and chromatin immunoprecipitation (ChIP) sequencing workflows• Oversee, plan, and execute studies in support of Business Development group• Primary lead on optimization studies on the MGI sequencing platform with the goal of comparing data across multiple sequencing instruments• Acquire biological samples for projects across different… Show more • Collaborate with team leads to develop and optimize protocols to investigate the role of higher-order genome structures, including methylation and chromatin immunoprecipitation (ChIP) sequencing workflows• Oversee, plan, and execute studies in support of Business Development group• Primary lead on optimization studies on the MGI sequencing platform with the goal of comparing data across multiple sequencing instruments• Acquire biological samples for projects across different research departments; supervise development of DNA sample bank• Presented data and progress updates at R&D meetings with Senior Leadership and cross-functional project teams Show less

Pleasanton, California, United States

• Hired, trained and managed cohort of Scientists for the research department; performed employee evaluations of up to 7 direct reports at a time• Led assay team on an expansive and interdisciplinary oncology research project with various partnerships and ongoing experiments; managed clinical sample receipt and inventory• Created, developed, and taught classroom curriculum and wet lab training courses (NGS Academy)) on library preparation and target enrichment for diverse research and… Show more • Hired, trained and managed cohort of Scientists for the research department; performed employee evaluations of up to 7 direct reports at a time• Led assay team on an expansive and interdisciplinary oncology research project with various partnerships and ongoing experiments; managed clinical sample receipt and inventory• Created, developed, and taught classroom curriculum and wet lab training courses (NGS Academy)) on library preparation and target enrichment for diverse research and cross-functional groups across Roche sites• Served as an independent scientific subject matter expert reviewer for projects in development • Led weekly classroom scientific educational sessions covering relevant molecular biology topics • Part of 4-member taskforce to consolidate and reconfigure research department-wide lab spaces to improve work efficiency; coordinated department move from Development to Research labs Show less

Pleasanton, Ca

• Led and authored Technical Performance Verification (TPV) studies for the Next Generation HyperCap project, planning and executing experiments to meet product requirements.• Supervised optimization and troubleshooting during early product development, including sample and library preparation and target enrichment, utilizing established and innovative procedures and approaches• First author on cfDNA quantification paper (Quantitative PCR Based Method to Assess Cell-Free DNA Quality… Show more • Led and authored Technical Performance Verification (TPV) studies for the Next Generation HyperCap project, planning and executing experiments to meet product requirements.• Supervised optimization and troubleshooting during early product development, including sample and library preparation and target enrichment, utilizing established and innovative procedures and approaches• First author on cfDNA quantification paper (Quantitative PCR Based Method to Assess Cell-Free DNA Quality, Adjust Input Mass, and Improve Next-Generation Sequencing Assay Performance)• Trained new employees and visiting scientists on DNA extraction and NGS library preparation assays Show less

Pleasanton, California, United States

• Prepared Next Generation Sequencing (NGS) libraries for sequencing utilizing both established (AVENIO ctDNA and Tumor Tissue assays) and novel protocols• Sequenced NGS libraries on the Illumina NextSeq, HiSeq, and NovaSeq instruments• Participated in TPV performance and concordance studies for the AVENIO Tumor Tissue assay. • Optimized DNA extraction and library prep with PDWB samples with the goal of writing a white paper on PDWB to accompany the AVENIO Tumor Tissue assay… Show more • Prepared Next Generation Sequencing (NGS) libraries for sequencing utilizing both established (AVENIO ctDNA and Tumor Tissue assays) and novel protocols• Sequenced NGS libraries on the Illumina NextSeq, HiSeq, and NovaSeq instruments• Participated in TPV performance and concordance studies for the AVENIO Tumor Tissue assay. • Optimized DNA extraction and library prep with PDWB samples with the goal of writing a white paper on PDWB to accompany the AVENIO Tumor Tissue assay kit• Analyzed library prep and sequencing results to form conclusions and determine next experimental steps Show less

Hercules, Ca

• Built and maintained a standard operating procedure (SOP) system• Performed high quality experiments on time and in compliance with SOPs• Independently prioritized and completed tasks• Identified, communicated, and resolved study issues that impacted budget, resources, and timelines• Navigated changing plans, timelines, and competing priorities while being proactive and flexible• Trained clients and new employees on the next generation genotyping (NGG) library… Show more • Built and maintained a standard operating procedure (SOP) system• Performed high quality experiments on time and in compliance with SOPs• Independently prioritized and completed tasks• Identified, communicated, and resolved study issues that impacted budget, resources, and timelines• Navigated changing plans, timelines, and competing priorities while being proactive and flexible• Trained clients and new employees on the next generation genotyping (NGG) library assay• Managed, tracked, and performed the NGG assay on at least 2000 samples a week for sequencing• Coordinated the sample indexing of all NGG libraries prepared each week• Created prototypes of NGG library preparation kits for product launch• Manufactured kits for shipment to clients after product launch• Developed and managed user manuals for NGG kits Show less

Emeryville, Ca

• Established roles, managed workflows, and participated in weekly teleconferences with the Covance Dedham Antibody Products site• Analyzed experimental data from various molecular biology assays, wrote batch record reports, summarized and communicated results to product inventory manager and marketing team• Provided daily technical and presentation support to the sales department for customer questions and complaints• Trained and supervised part-time lab assistant in conducting… Show more • Established roles, managed workflows, and participated in weekly teleconferences with the Covance Dedham Antibody Products site• Analyzed experimental data from various molecular biology assays, wrote batch record reports, summarized and communicated results to product inventory manager and marketing team• Provided daily technical and presentation support to the sales department for customer questions and complaints• Trained and supervised part-time lab assistant in conducting routine assays to enable the research and development of new antibodies• Developed and did troubleshooting on lab assay protocols for streamlining of quality control processes• Ran on average three assays (such as western blots, immunofluorscence, and immunoprecipitation) for evaluation of antibodies per week• Performed weekly Protein A, Protein G, and Peptide Affinity purifications on the AKTA FPLC system to restock product inventory• Coupled antibodies with matrix beads, fluorescent dyes and biotin for product inventory on a weekly basis• Managed inventories of hybridoma and immortal cell lines • Grew immortal cell lines for use in cell staining and for use as whole cell lysates to support product quality control assays• Maintained lab supplies, calibration schedules of all lab equipment, and hazardous waste inventory and disposal• Created and updated all SOPs pertaining to the lab including all lab processes and equipment maintenance• Created electronic filing system for managing batch records for all antibodies tested/purified in Emeryville lab• Conducted most of the western blots, and all purifications and all cell staining assays in the research and development of approximately 80 new antibody products to be added to product catalog in 2012 Show less

Certificate In Clinical Research Conduct And Management

• Introduction to Clinical Research: Clinical Trial Phases and Design, GCP • Clinical Trial Planning: Protocol Development, Data.

Bachelor'S Degree, Molecular Cell Biology

Activities and Societies: Alpha Phi Omega