Serena Silver

Serena Silver Email and Phone Number

Chief Scientific Officer @ Accent Therapeutics, Inc.
Cambridge, MA, US
Serena Silver's Location
Cambridge, Massachusetts, United States, United States
Serena Silver's Contact Details

Serena Silver personal email

n/a
About Serena Silver

Innovative and creative scientific leader, skilled in strategic planning, complex collaborations, and building diverse teams to enable effective experimental design, implementation, and analysis; Expertise across the drug discovery process, from Target Discovery and Validation to in vivo pharmacology and translational research; Proven leadership in portfolio strategy, disease selection and portfolio prioritization; Key player in multiple highly productive scientific and strategic partnerships with industry and academia; Deep expertise in biology platforms to accelerate drug discovery for cancer biology and rare disease; broad experience with RNAi, CRISPR and chemical genetics, disease model building, and pharmacology.

Serena Silver's Current Company Details
Accent Therapeutics, Inc.

Accent Therapeutics, Inc.

View
Chief Scientific Officer
Cambridge, MA, US
Website:
accenttx.com
Employees:
33
Serena Silver Work Experience Details
  • Accent Therapeutics, Inc.
    Chief Scientific Officer
    Accent Therapeutics, Inc.
    Cambridge, Ma, Us
  • Accent Therapeutics, Inc.
    Vice President Of Biology
    Accent Therapeutics, Inc. Sep 2022 - Present
    Lexington, Massachusetts, Us
  • Fulcrum Therapeutics
    Vice President, Discovery Biology & Technologies
    Fulcrum Therapeutics Jul 2021 - Aug 2022
    Head of Discovery Biology & Technologies organization, including Target Discovery, Cell Biology and Target Validation, cell assays for lead optimization, in vivo pharmacology, and technology platforms for target and drug discovery (lab automation, imaging, RNAseq and scRNAseq). Managed biology resources and budget to drive drug discovery.
  • Fulcrum Therapeutics
    Senior Director, Discovery Biology
    Fulcrum Therapeutics Jul 2020 - Jun 2021
  • Fulcrum Therapeutics
    Director, Discovery Biology
    Fulcrum Therapeutics Apr 2019 - Jul 2020
  • Novartis Institutes For Biomedical Research
    Senior Investigator Ii, Head Of Molecular Pharmacology
    Novartis Institutes For Biomedical Research Sep 2017 - Apr 2019
    Basel, Baselstadt, Ch
    Directed a multidisciplinary department focused on novel assay development to interrogate cancer target biology, and to enable drug discovery and indication expansion. As a member of Oncology Drug Discovery Leadership team (ODD-LT), contributed to portfolio review, strategic planning for new areas of focus, and decision making around resourcing and prioritization.
  • Novartis Institutes For Biomedical Research
    Senior Investigator I, Head Of Molecular Pharmacology
    Novartis Institutes For Biomedical Research Nov 2013 - Nov 2017
    Basel, Baselstadt, Ch
  • Sanofi
    Lead Research Investigator, Section Head Target Discovery
    Sanofi Mar 2013 - Oct 2013
    Paris, France, Fr
    Led development and maintenance of a robust early pipeline for Sanofi Oncology. Managed initiatives of the Target ID and Validation group in a highly matrixed environment.
  • Sanofi
    Principal Research Investigator
    Sanofi Mar 2011 - Mar 2013
    Paris, France, Fr
    Head of research team which conducted and analyzed functional genomics and chemical screens, as single agents and in combination, to identify new targets and expand indications for existing molecules in Sanofi pipeline.
  • Broad Institute
    Group Leader, Rnai Screening Projects
    Broad Institute May 2006 - Mar 2011
    Cambridge, Ma, Us
    Group leader within the RNAi Platform to design and execute large scale RNAi screens in mammalian tissue culture using lentivirus-based shRNA library, collaborating across diverse project areas, including cancer research, infectious disease, and metabolic disease.
  • Harvard Medical School
    Postdoctoral Fellow
    Harvard Medical School May 2004 - May 2006
    Boston, Ma, Us
    Primary Project: Identify and characterize the role of miRNAs in Signal Transduction networks. Utilized cell-based assays to screen miRNAs for cellular function and validated findings in vivo; led to identification of miR-315 as a potent activator of Wnt signaling.Secondary Project: Determine the extent and nature of “off-target” effects in the Drosophila RNAi Screening Center (DRSC) dsRNA collection through analysis of data from over 40 genome-wide RNAi screens in Drosophila cells.
  • Mit
    Graduate Student
    Mit 1999 - 2004
    Cambridge, Ma, Us
    Investigation of the effects of Ras/MAPK signaling on the transcription factor EYES ABSENT, and demonstration that this protein also functions as a novel protein tyrosine phosphatase.
  • Whitehead Institute
    Graduate Student
    Whitehead Institute 1999 - 2004

Serena Silver Skills

Molecular Biology High Throughput Screening Assay Development Cell Biology Drug Discovery Biochemistry Genomics Rnai Genetics Cell Cell Culture Cancer Cancer Research In Vivo Flow Cytometry Fluorescence Microscopy In Vitro

Serena Silver Education Details

  • Massachusetts Institute Of Technology
    Massachusetts Institute Of Technology
    Biology
  • New York University
    New York University
  • New York University
    New York University
    English & American Literature

Frequently Asked Questions about Serena Silver

What company does Serena Silver work for?

Serena Silver works for Accent Therapeutics, Inc.

What is Serena Silver's role at the current company?

Serena Silver's current role is Chief Scientific Officer.

What is Serena Silver's email address?

Serena Silver's email address is ss****@****mit.edu

What schools did Serena Silver attend?

Serena Silver attended Massachusetts Institute Of Technology, New York University, New York University.

What skills is Serena Silver known for?

Serena Silver has skills like Molecular Biology, High Throughput Screening, Assay Development, Cell Biology, Drug Discovery, Biochemistry, Genomics, Rnai, Genetics, Cell, Cell Culture, Cancer.

Who are Serena Silver's colleagues?

Serena Silver's colleagues are Gordon J Lockbaum, Shihua Yao, David Brennan, Taylor Hotz, Kevin Mcgann.

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