• Founding member of scientific team• Directed all scientific efforts including design, synthesis, ADME studies, in vitro cell studies, PK studies, and xenograft studies.• Led an external chemistry team of 10 FTE scientists.

• Developed and characterized drug conjugates for controlled, extended release.• Project manager responsible for design, synthesis, evaluation, lead optimization, and lead selection of PEGylated topoisomerase, PARP, and other inhibitors of DNA damage response.• Managed external alliances with 4 CROs, 5 academic groups, and 2 industry partners coordinating activities including synthesis, pharmacokinetics, toxicity, PET imaging, and tumor xenograft studies.

• Investigated 1,2,4-trioxolane drug conjugates for the selective delivery of antimalarial agents to malaria parasites in infected host systems.

•Investigated [4+2] cycloadditions of iminoacetonitriles including enantioselectve and catalytic variants as well as their use as the key-step in the total synthesis of Quinolidizine 207I.

Undergraduate Research Assistant in the Burkart Laborartory. • Synthesized late-stage intermediates and optimized problematic reactions for the synthesis of mycolactone.

Synthesized intermediates and lead compounds for preliminary biological screening

Provided assistance for large scale preparation of lead compounds