Shaguna Seth Phd Email & Phone Number

Durham, North Carolina, Us

Technical and Business Strategy Advisor to CEO and Executive Team, Operational and Business Excellence

Bothell, Wa, Us

Bothell, Wa, Us

Bothell, Wa, Us

• Responsible for Scientific Strategy and program management of disease portfolio of influenza and tetanus vaccine (Virus-Like Particles) microneedle based delivery agents and therapeutic peptides from non-coding RNA (small RNA, long non-coding RNA, miRNA) using system biology approach.• in vitro screening and proof-of-concept studies in animal disease models, Pharmacology and toxicology of drug candidates from preclinical proof-of-concept to IND filing.• Initiating/managing research collaborations with academia, biotech companies and CROs.

Seattle, Washington, Us

Provide scientific expertise and business assessment to biotechnology startup companies originating from University of Washington, Seattle WA. Help pitch the technology to Venture Capitalist and Angel Investors for transition from academic lab setting to a DNA detection-based biotech startup.Scientific (in vitro and in vivo toxicology testing) strategy in development/expansion of technology portfolio in biotechnology start-ups at UW C4C (DANPY-Nucleic acid based reagents).

Pittsburgh, Pa, Us

Fund-raising by soliciting biotechnology and pharmaceutical companies for sponsorship opportunities in educational programs towards the success of women entrepreneurs, executives, scientists, professionals and students in the life sciences industry.

City Of Industry, Ca, Us

Oversee and serve as the technical lead in guiding the GLP-level bio-analytical assays on human tissues encompassing gene expression based biomarker determination, immunological profile in patient samples from Phase Ib oncology trial. Led a team of PhD level scientists and Research Associates in providing scientific direction and all aspects of troubleshooting in the screening/validation of siRNA and miRNA based single and double-stranded drug candidates and delivery agents for oncology, pulmonary diseases and metabolic indications. Provide scientific expertise towards development of animal disease models (Orthotopic liver cancer, ovarian cancer and bladder cancer) for efficacy, proof-of-concept studies in mice, PK/PD profile of drug candidates, toxicology analysis and immunological aspects of lead candidates in rodents and no-human primate model systems.Provide scientific expertise in collaborations with pharmaceutical companies, academic institutions, government agencies (CDC, Atlanta GA) and CROs. Co-manage scientific due diligence of technology based assets, assessing strategic fit and developability for in-licensing opportunities.Assist the SVP business development in providing scientific/preclinical representation to potential collaborators in liaison with business development.Present and communicate scientific data demonstrating progress in drug discovery programs internally to Chief Scientific Officer, the executive team and the board of directors. Also present scientific findings in national and international conferences to scientific audience describing core technologies developed internally.Write and review research articles, book chapter and collaborative research manuscripts describing scientific data for peer reviewed journals.

Manage and provide leadership (manage a team of 5 scientists) towards NIH-funded R01 and SBIR grants for generation of RNA based therapeutics for oncology, metabolic diseases and infectious diseases.Provide scientific direction towards discovery, proof-of-concept and preclinical efficacy and toxicology based IND-enabling studies focussed on cancer (solid cancers: Liver, Bladder and Ovarian), autoimmunity (TNFα, IL6), metabolic diseases (ApoB and PCSK9) and infectious diseases (Influenza and other human respiratory diseases) using peptide and lipid based nanoparticles harboring single-stranded or double- stranded oligonucleotides.Co-managed technology assessments for in-licensing opportunities and detailed report generation.

Atlanta, Ga, Us

Atlanta, Ga, Us

Certificate Program, Biomedical Regulatory Affairs

Doctor Of Philosophy (Phd), Microbiology And Cell Biology

Master Of Science (M.S.), Genetics

Bachelor Of Science (B.S.), Zoology (Honors)