Shahulhameed Liyakathali Email & Phone Number

Oxford, England, United Kingdom

• As part of a Hepatic Target Discovery group, my primary role is to identify and validate hepatocyte-specific drug targets for T2D and CVDs.
• Directed cross-functional project teams to validate drug targets using human-centric in vitro models and disease-relevant functional assays.
• As a pre-project manager, generated in vitro data using human primary cells and collaborated with geneticists and computational biologists to develop target packages.
• Played a pivotal role in developing disease-relevant models and assays to understand disease biology and identify new drug targets.
• Worked with primary cells (hepatocytes, stellate cells), cell lines (Huh7, HepG2, EndoC), iPSCs.
• Collaborated with various of stakeholders to progress the targets through the value chain.

Copenhagen, Capital Region, Denmark

• I performed my Job Rotation in Translational Medicine department as a Translational lead.
• Primary role is to identify target engagement biomarkers for drug targets which are potentially progressing towards clinical trails as part of a team.
• Participated in biomarker discovery effort for two different projects in rare disease area.
• Exposed to precision medicine strategy and companion diagnostics
• Expanded knowledge base to new therapeutic areas, such as rare diseases

Oxford, England, United Kingdom

• Contributed to studying the impact of Gluco- and Lipotoxicity in EndoC cell lines.
• Studied the impact of microtubule inhibitors on hepatic glucose production.
• Involved in maintaining iPSCs
• Proposed new project idea for target discovery in an internal site-wide meeting
• Engaged with a number of stakeholders

Stockholm, Sweden

• Obtained PhD degree from Karolinska Institute in Cell and Molecular Biology within Neuroscience and Regenerative Medicine.
• Evaluated the role of reactive oxygen species on neural stem cells in vivo and in vitro
• Studied the differentiation potential of neural stem cells towards astrocytes
• Taught cell biology to medical students for 3+ years
• Published 5 scientific articles in high-profile peer-reviewed journals
• Presented research results to diverse audiences (group meetings, international conferences, seminars)

Gurgaon, India

• Studied the impact of neural stem cells on learning and behaviour using in vivo and in vitro model
• Investigated auditory cortex developed using histology staining in primary human brain tissue.
• Worked independently and as a team to publish 3 papers in high impact peer-reviewed journals

Doctor Of Philosophy - Phd, Medical Sciences

Activities and Societies: Handled three different projects dealing with Neuronal regeneration, Brain development, and tumor induction..

Master'S Degree, Medical Biochemistry, 76%

Activities and Societies: Participated in the number of seminars and sports activities at the university level.Apart from participating in.

Bachelor'S Degree, Biochemistry, 76%

Activities and Societies: College level Topper. Participated and won medals in the sports events.