Shahulhameed Liyakathali Email & Phone Number

Oxford, England, United Kingdom

As part of a Hepatic Target Discovery group, my primary role is to identify and validate hepatocyte-specific drug targets for T2D and CVDs.• Directed cross-functional project teams to validate drug targets using human-centric in vitro models and disease-relevant functional assays. • As a pre-project manager, generated in vitro data using human primary cells and collaborated with geneticists and computational biologists to develop target packages. • Played a pivotal role in developing disease-relevant models and assays to understand disease biology and identify new drug targets.• Worked with primary cells (hepatocytes, stellate cells), cell lines (Huh7, HepG2, EndoC), iPSCs. • Collaborated with various of stakeholders to progress the targets through the value chain.• As part of a project team, published 2 scientific articles in high-profile peer-reviewed journals.

Copenhagen, Capital Region, Denmark

I performed my Job Rotation in Translational Medicine department as a Translational lead. • Primary role is to identify target engagement biomarkers for drug targets which are potentially progressing towards clinical trails as part of a team.• Participated in biomarker discovery effort for two different projects in rare disease area. • Exposed to precision medicine strategy and companion diagnostics• Expanded knowledge base to new therapeutic areas, such as rare diseases

Oxford, England, United Kingdom

• Contributed to studying the impact of Gluco- and Lipotoxicity in EndoC cell lines. • Studied the impact of microtubule inhibitors on hepatic glucose production. • Involved in maintaining iPSCs• Proposed new project idea for target discovery in an internal site-wide meeting• Engaged with a number of stakeholders

Stockholm, Sweden

Obtained PhD degree from Karolinska Institute in Cell and Molecular Biology within Neuroscience and Regenerative Medicine.• Evaluated the role of reactive oxygen species on neural stem cells in vivo and in vitro • Studied the differentiation potential of neural stem cells towards astrocytes• Taught cell biology to medical students for 3+ years• Published 5 scientific articles in high-profile peer-reviewed journals • Presented research results to diverse audiences (group meetings, international conferences, seminars)• Reviewed scientific and technical literature• Developed ability to analyse and communicate science

Gurgaon, India

• Studied the impact of neural stem cells on learning and behaviour using in vivo and in vitro model• Investigated auditory cortex developed using histology staining in primary human brain tissue. • Worked independently and as a team to publish 3 papers in high impact peer-reviewed journals

Doctor Of Philosophy - Phd, Medical Sciences

Activities and Societies: Handled three different projects dealing with Neuronal regeneration, Brain development, and tumor induction..

Master'S Degree, Medical Biochemistry, 76%

Activities and Societies: Participated in the number of seminars and sports activities at the university level.Apart from participating.

Bachelor'S Degree, Biochemistry, 76%

Activities and Societies: College level Topper. Participated and won medals in the sports events.