Shail Rakesh Modi, Phd Email & Phone Number

Houston, Tx, Us

Boston, Ma, Us

• Identified master regulators and their transcriptional network using TCGA datasets by utilizing R language and other computational tools. Validated the molecular targets by siRNA silencing of genes in breast cancer cell lines and employing luciferase gene reporter assay, and co-immunoprecipitation analysis. • Evaluated the combination effect of Piperlongumine with EGFR-TKIs (erlotinib, gefitinib) to reverse desensitization in mutated lung cancer cells• Performed cell viability studies in lung cancer and breast cancer cells. Investigated mechanism of action through flow cytometry analysis, western blot method, and fluorescence staining.• Assessed dysregulated and overexpressed genes between COVID-19 patients and healthy volunteers and identified genes associated with cytokine storm and T-cell signaling pathways to be upregulated in COVID-19 patients. • Utilized different machine learning models to characterize the receptor status of an uncharacterized patient dataset from TCGA data.

Boston, Ma, Us

- Mentored and trained PharmD students in their research activities- Engaged in collaborative efforts within and between labs, involving negotiation and coordinating reagent/equipment procurement- Assisted professors in conducting lab courses and providing support as a knowledge resource

Teaneck, New Jersey, Us

- Supported Sanofi as a client in the pharmacovigilance department, ensuring compliance with regulatory requirements and conducting case assessments for drugs under clinical trials in the therapeutic areas of Diabetes and Oncology

Thane , Maharashtra, In

- Developed analytical methods for small-molecule drugs for different formulated products, both for clients and in-house formulations via HPLC and dissolution followed by validation in a US FDA-approved facility.

-Investigated pharmacological activities of two newly synthesized drugs, 4-thiazolidione and 1,3,4 - thiadiazoles- Performed in-vitro and in-vivo analysis to analyze the toxicity of the compounds along with anti-inflammatory and analgesic activity.

Mumbai, Maharashtra, In

Summer internship to get exposure to the pharmaceutical industry. Working in different departments such as formulation, quality control, analytical lab to understand different processes.

Doctor Of Philosophy - Phd, Pharmacology

Master'S Degree, Pharmacy (Quality Assurance)

Bachelor Of Pharmacy (Bpharm), Pharmacy