Shaji Chacko Email and Phone Number

- Chacko SK, Ordonez J, Sauer PJJ, Sunehag AL: Gluconeogenesis is not regulated by either glucose or insulin in extremly low birth weight infants receiving TPN. Journal of pediatrics 2011.- Chacko SK, Sunehag AL: Gluconeogenesis continues in premature infants receiving total parenteral nutrition. Arch Dis Child Fetal Neonatal Ed 2010- Chacko SK, Sunehag AL, Sharma S, Sauer PJ, Haymond MW: Measurement of gluconeogenesis using glucose fragments and mass spectrometry after ingestion of deuterium oxide. J Appl Physiol 2008.- Riedijk MA, Stoll B, Chacko S, Schierbeek H, Sunehag AL, van Goudoever JB, Burrin DG: Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract. Proc Natl Acad Sci USA 2007.- Chung ST, Chacko SK, Sunehag AL, Haymond MW. Measurements of Gluconeogenesis and Glycogenolysis: A Methodological Review. Diabetes.2015 - Webster CC, Noakes TD, Chacko SK, Swart J, Kohn TA, Smith JA. Gluconeogenesis during endurance exercise in cyclists habituated to a long-term low carbohydrate high fat diet. J Physiol. 2016- Axelsson AS, Tubbs E, Mecham B, Chacko S, Nenonen HA, Tang Y, Fahey JW, Derry JMJ, Wollheim CB, Wierup N, Haymond MW, Friend SH, Mulder H, Rosengren AH. Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 Diabetes.Sci Transl Med. 2017.- Chung ST, Courville AB, ..., Walter PJ, Garraffo HM, Chacko S, Haymond MW, Sumner AE. Gluconeogenesis and risk for fasting hyperglycemia in Black and White women. JCI Insight.2018.- Sekizkardes H, Chung ST, Chacko S, Haymond M, Startzell M, Walter M, Walter PJ, Lightbourne M, Brown RJ. Free fatty acid processing diverges in human pathologic insulin resistance conditions. J Clin Invest.2020.- Baykal AP, Parks EJ, Shamburek R, Syed-Abdul MM, Chacko S, Cochran E, Startzell M, Gharib AM, Ouwerkerk R, Abd-Elmoniem KZ, Walter PJ, Walter M, Muniyappa R, Chung ST, Brown RJ. Leptin decreases de novo lipogenesis in patients with lipodystrophy. JCI Insight. 2020- Quaye E, Chacko S, Chung S, Brychta R, Chen K, Brown R. Energy expenditure due to gluconeogenesis in pathologic conditions of insulin resistance. Am J Physiol Endocrinol Metab 2021.- Tan HC, Hsu JW, Tai ES, Chacko S, Wu V, Lee CF, Kovalik JP, Jahoor F. De Novo Glycine Synthesis Is Reduced in Adults With Morbid Obesity and Increases Following Bariatric Surgery. Front Endocrinol (Lausanne).2022.- Zhong S, Chèvre R, ......., Chacko S, Flannick J, Sim X, Tan HC, Singaraja RR.Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans. J Clin Invest.2022