𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Leading Innovative Research Initiatives: Spearheading cutting-edge research projects aimed at advancing process development, synthesis methodologies, and novel compound discovery within Chemazon Laboratories. ❖ Innovating Synthetic Processes: Leading the development of a synthetic process for 4-amino-2-mercaptophenol hydrochloride, contributing to the advancement of pharmaceutical synthesis methodologies. ❖ Scale-Up Synthesis:… Show more 𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Leading Innovative Research Initiatives: Spearheading cutting-edge research projects aimed at advancing process development, synthesis methodologies, and novel compound discovery within Chemazon Laboratories. ❖ Innovating Synthetic Processes: Leading the development of a synthetic process for 4-amino-2-mercaptophenol hydrochloride, contributing to the advancement of pharmaceutical synthesis methodologies. ❖ Scale-Up Synthesis: Successfully synthesized non-2-yn-1-ol compound in quantities up to 2 kilograms, demonstrating proficiency in large-scale synthesis techniques and ensuring consistent product quality. ❖ Process Development Expertise: Leading the synthesis and process development efforts for tert-butyl (S)-6-hydroxy-6-methyl-1,4-oxazepane-4- carboxylate, facilitating the expansion of the chemical library with potential pharmaceutical applications. ❖ Collaborating Across Disciplines: Collaborating with cross-functional teams to integrate diverse perspectives and expertise, fostering a culture of innovation and collaboration to tackle complex scientific challenges. ❖ Optimizing Process Efficiency: Continuously evaluating and optimizing process efficiency to streamline operations, reduce costs, and accelerate project timelines, driving productivity and innovation. ❖ Identifying Emerging Opportunities: Proactively identifying emerging trends and opportunities in the pharmaceutical landscape, guiding strategic decision-making and investment in promising research areas. ❖ Establishing Strategic Partnerships: Cultivating strategic partnerships with academic institutions, industry collaborators, and research organizations to enhance Chemazon Laboratories' research capabilities and drive collaborative innovation. Show less

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Spearheaded Agrichem Projects: Led the synthesis initiatives for agrichemical compounds, including Azoxystrobin, Haloxyfop-(R)-Methyl, and Propyzamide, overseeing process research and development as well as impurity synthesis.❖ Conducted Process R&D: Conducted extensive research and development activities to optimize synthesis processes, enhance product yields, and improve overall efficiency in agrichemical.❖ Contributed to… Show more 𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Spearheaded Agrichem Projects: Led the synthesis initiatives for agrichemical compounds, including Azoxystrobin, Haloxyfop-(R)-Methyl, and Propyzamide, overseeing process research and development as well as impurity synthesis.❖ Conducted Process R&D: Conducted extensive research and development activities to optimize synthesis processes, enhance product yields, and improve overall efficiency in agrichemical.❖ Contributed to Cross-Functional Collaboration: Collaborated closely with interdisciplinary teams including chemists, engineers, and regulatory experts, facilitating seamless integration of project goals and objectives across departments for successful project execution Show less

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Led Medicinal Chemistry Projects: Directed and managed medicinal chemistry projects at Sambi Pharma, focusing on the discovery and development of new therapeutic compounds through full-time research work (FT-work).

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Conducted Process R&D Projects: Led Process R&D projects and cost reduction initiatives, contributing to the optimization of manufacturing processes and enhancing operational efficiency within KEMINNTEK LABORATORIES in Hyderabad, India.❖ Synthesized Substituted Cathinone Compounds: Led projects focused on the synthesis of compounds belonging to the substituted cathinone class, demonstrating expertise in organic synthesis and medicinal… Show more 𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Conducted Process R&D Projects: Led Process R&D projects and cost reduction initiatives, contributing to the optimization of manufacturing processes and enhancing operational efficiency within KEMINNTEK LABORATORIES in Hyderabad, India.❖ Synthesized Substituted Cathinone Compounds: Led projects focused on the synthesis of compounds belonging to the substituted cathinone class, demonstrating expertise in organic synthesis and medicinal chemistry.❖ Executed Route of Synthesis (ROS): Developed and executed routes of synthesis (ROS), overseeing reactions and coordinating with chemists to ensure the smooth progress of projects on a day-to-day basis, facilitating the timely completion of objectives and milestones. Show less

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Synthesis of 4H-chromene-3,4-dicarboxylate derivatives via an isocyanide-based one-pot three component reaction.❖ Synthesis of benzo[a]anthracen-5-one, phenazine-8, 9-diol, pyrido[2,3-b] quinoxaline-7,8-diol and their derivatives.

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– June 2012-August 2014 with as Associate Research Scientist❖ Performed Process R&D-projects (CRAMS), done Ethacrynic acid synthesis in Kg scale API and Prepared Process Development Report (PDR).❖ Success fully delivered Montelukast API-intermediate and prepared Feasibility report for Route-I and Route-II synthesis.

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Diligently carried out the research based on the development of novel medicinal agents with drug abuse and addiction application, based on our modeling studies.❖ Efficiently worked on a series of novel Naltrexamine derivatives are designed and synthesized.❖ Successfully administered Total synthesis of Anibamine core unit compounds: Total synthesis of Anibamine core unit library of compounds for chemokine receptor, CCR5 antagonist as novel… Show more 𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Diligently carried out the research based on the development of novel medicinal agents with drug abuse and addiction application, based on our modeling studies.❖ Efficiently worked on a series of novel Naltrexamine derivatives are designed and synthesized.❖ Successfully administered Total synthesis of Anibamine core unit compounds: Total synthesis of Anibamine core unit library of compounds for chemokine receptor, CCR5 antagonist as novel anti-HIV agent and prostate cancer activity.❖ Ascertained five step chemical synthesis of Tirofiban structural analogs as an anti-platelet molecule (anticoagulant), reductive amination with Dextran sulfate sodium salt as a key step reaction. Show less

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Stellar in monitoring the design, synthesis, and biological active compounds like Neuroprotective agents: 47 compounds of 3-Substituted indolones have been synthesized and evaluated their biological activity.❖ Successfully developed more than 100 compounds neuroprotective 3’-substituted indolin-2-one derivatives and 35 of 1, 4-Benzoxazine compounds as novel class of neuroprotective agents and new method on “benzyne generated copper-catalyzed… Show more 𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Stellar in monitoring the design, synthesis, and biological active compounds like Neuroprotective agents: 47 compounds of 3-Substituted indolones have been synthesized and evaluated their biological activity.❖ Successfully developed more than 100 compounds neuroprotective 3’-substituted indolin-2-one derivatives and 35 of 1, 4-Benzoxazine compounds as novel class of neuroprotective agents and new method on “benzyne generated copper-catalyzed alkyne-aryne coupling” under microwave conditions.❖ Instrumental in communicating effectively with different levels of management. Show less

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔 – • Looked after the synthesis of:❖ Eicosanoids analogues and pyrophosphates.❖ DDMS: DDMS (10, 10-Dibromo-N-(methylsulfonyl) dec-9-enamide) synthesized from commercially available Methyl oleate.❖ Arachidonic acid derivatives: Synthesis of 14, 15-EET and 11, 12-EET.

𝑲𝒆𝒚 𝑹𝒆𝒔𝒑𝒐𝒏𝒔𝒊𝒃𝒊𝒍𝒊𝒕𝒊𝒆𝒔– ❖ Gained extensive exposure for drug intermediates basic R &D and Process R & D projects.❖ Carried out multi step, medicinal chemistry synthesis of Drug intermediates with GMP standards: Synthesis of 1, 3, 5-triazine derivatives and glycosidation reaction on sugar derivatives, Metabasis and SuperGen projects.❖ Instrumentally scaled up-synthesis of halogenations reaction on p-toluene sulfonic acid