Shaun Chen
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Shaun Chen Email & Phone Number

Data Scientist at Sapient
Location: San Diego, California, United States 10 work roles 3 schools
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Current company
Role
Data Scientist
Location
San Diego, California, United States
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Who is Shaun Chen? Overview

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Shaun Chen is listed as Data Scientist at Sapient, a with 45 employees, based in San Diego, California, United States. AeroLeads shows a matched LinkedIn profile for Shaun Chen.

Shaun Chen previously worked as Data Scientist II at Sapient and Postdoctoral Researcher at Scripps Research. Shaun Chen holds Doctor Of Philosophy - Phd, Biological And Biomedical Sciences from The Scripps Research Institute.

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Sapient

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Profile bio

About Shaun Chen

At the forefront of predictive genomics, my work at Scripps Research have been dedicated to innovating healthcare through bioinformatics. My recent achievements include developing a SHAP-based explainable AI framework for disease risk prediction and integrating a genotype imputation pipeline that delivers rapid results during clinical visits. My work embodies a commitment to advancing disease prevention and treatment, training machine learning/deep learning models from biobank with vast genomic datasets and longitudinal electronic health records. The goal is to empower physicians and patients with actionable insights, transforming the landscape of clinical trials and personalized medicine.

Listed skills include Primary Cell Isolation, Multi Color Flow Cytometry, Scientific Analysis, Scientific Writing, and 17 others.

Current workplace

Shaun Chen's current company

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Sapient
Sapient
Data Scientist
San Diego, CA, US
Website
Employees
45
AeroLeads page
10 roles

Shaun Chen work experience

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Data Scientist

San Diego, Ca, Us

Data Scientist Ii

San Diego, Ca, Us

Postdoctoral Researcher

San Diego, California, United States

- Machine Learning (ML) for Risk Prediction and Targeted Interventions: Developed multi-task SHAP-explained risk prediction framework for complex common diseases using UK Biobank, All of Us and eMERGE (>1 million individuals) integrated with multi-modal data. Processed longitudinal EHR data, including mapping PheCode with UK (ICD-9/10, OPCS) and US (SNOMED, CPT) systems. Enabled personalized medicine through polygenic risk stratification integrated with EHR, enhancing clinical decision-making in line with clinical guideline.- Scalable PRS Pipeline for Real-Time Clinical Utility: Implemented bioinformatics pipeline for MyGeneRank [https://mygenerank.scripps.edu] and PEPRS clinical trials. Integrated the multidisciplinary efforts of mobile app software engineers, physicians, and statisticians. Delivered ancestry-adjusted percentile ranking PRSs from whole genome data within 6 minutes, allowing results to be available during clinical visits.- Deep Learning (DL) for Genotype Imputation: Supported the development of a reference-free deep-learning genotype imputation method using autoencoder. Modeled haplotype structures from large-scale, multi-ancestral whole genome data (1000 Genomes, HRC, HGDP, Wellderly, TOPMed; ~200k individuals). Achieved a 4x increase in speed, improving generalizability and accuracy while enhancing accessibility by eliminating reliance on restricted reference panels.- Ancestry-Specific PRS: Developed multi-ancestry PRS by combining global and ancestry-specific SNPs, prioritized using fine-mapping, functional annotation, and individualized similarity of subpopulation.- Leadership and Project Management: Mentored over 5 interns and junior graduate students, successfully coordinating complex projects. - Analytical Review: Applied critical thinking in peer review roles for high-impact journals, including npj Digital Medicine and npj Parkinson’s Disease.

Graduate Researcher

Greater San Diego Area

PhD Thesis: "Integrative polygenic risk prediction of coronary artery disease."

Jun 2018 - May 2024

Research Assistant

Topic: "Optimized Rejuvenation of adult stem cell by small molecules"

May 2017 - Jun 2018

Graduate Researcher

Taipei City, Taiwan

Master Thesis: Optimize the Methods of Reprogramming Chemically Induced Mesenchymal Stem Cells from Human Somatic Cells

Sep 2015 - May 2017

Research Intern

United States

Topic: "Quantitative detection of circulating tumor cells (CTCs) in prostate cancer patients by thermoresponsive NanoVelcro chips"

Jun 2015 - Sep 2015

Research Intern

Taipei City, Taiwan

Independent study in Dr. Hsiao-Chun Huang’s laboratory.Design synthetic regulatory networks of asymmetric cell division in Escherichia coli. .Regulation of gene expression by toggling switch circuit in Escherichia coli.

Jan 2014 - Jun 2015

Research Intern

United States

Topic: "Diagnosis of advanced prostate cancers with the morphological subset of circulating tumor cells by liquid biopsy"

Jun 2014 - Sep 2014

Research Intern

Taipei City, Taiwan

Independent study in Dr. Jiun-Hong Chen’s laboratory.Pathways of head regeneration and wound healing in Aeolosoma viride..In vitro toxicity of the organophosphorus compounds to Eisenia andrie.

Jul 2012 - Jul 2013
3 education records

Shaun Chen education

Doctor Of Philosophy - Phd, Biological And Biomedical Sciences

Activities and Societies: 2023 Teaching Assistant, Advanced Methods in Statistical Analysis 2022 Teaching Assistant, Molecular Medicine.

Master'S Degree, Molecular And Cellular Biology

Activities and Societies: 2016 Teaching Assistant, General Biology Lab Master Student in Dr. Hsiao-Chun Huang's group with Dr. Jean Lu.

FAQ

Frequently asked questions about Shaun Chen

Quick answers generated from the profile data available on this page.

What company does Shaun Chen work for?

Shaun Chen works for Sapient.

What is Shaun Chen's role at Sapient?

Shaun Chen is listed as Data Scientist at Sapient.

Where is Shaun Chen based?

Shaun Chen is based in San Diego, California, United States while working with Sapient.

What companies has Shaun Chen worked for?

Shaun Chen has worked for Sapient, Scripps Research, The Scripps Research Institute, Academia Sinica, Taiwan, and National Taiwan University.

How can I contact Shaun Chen?

You can use AeroLeads to view verified contact signals for Shaun Chen at Sapient, including work email, phone, and LinkedIn data when available.

What schools did Shaun Chen attend?

Shaun Chen holds Doctor Of Philosophy - Phd, Biological And Biomedical Sciences from The Scripps Research Institute.

What skills is Shaun Chen known for?

Shaun Chen is listed with skills including Primary Cell Isolation, Multi Color Flow Cytometry, Scientific Analysis, Scientific Writing, Confocal Microscopy, Molecular Cloning, Python, and R.

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