π Dr. Shivalee D Email and Phone Number
I am an accomplished Post-Doctoral Fellow specializing in immunology and infectious diseases. With a strong background in scientific research, I have excelled in prestigious institutions worldwide, conducting impactful studies in my field.Currently, I am a Post-Doctoral Fellow at the National Cancer Institute (NCI-NIH) in Frederick, Maryland, USA. Under the guidance of Dr. Mary Kearney I am elucidating the integration of retroviral vectors used for gene therapy of cancer patients.Previously, I worked as a Post-Doctoral Fellow at Aarhus University in Denmark, collaborating with STIPE therapeutics, Ltd. I researched the role of P62 in the early stages of STING activation for interferon release, contributing to our understanding of the innate immune response to viral infections.I obtained my Ph.D. at Friedrich Schiller University in Jena, Germany, under the supervision of Prof. Dr. Michael Bauer. My doctoral research focused on cytosolic innate immunity during sepsis, studying membrane vesicles secreted by Gram-positive bacteria and their role in inflammasome signaling pathways.Throughout my career, I have developed a diverse skill set in biochemical techniques, molecular biology, microscopy, and spectroscopy. I am experienced in data analysis and bioinformatics and possess strong scientific writing and editing skills.In addition to my research accomplishments, I am dedicated to scientific outreach and mentoring. I founded "Path2PhD," a mentoring initiative for aspiring PhD students, and represent the National Postdoc Association (NPA) at the National Institutes of Health (NIH). I have also shared my insights and experiences as a speaker and panelist in conferences and podcasts.I am driven by a desire to contribute to scientific knowledge and improve healthcare. Seeking opportunities in a dynamic research institute, I aim to continue my passion for scientific discovery, foster collaborations, and contribute to institutional and personal growth.Feel free to reach out to me at s.duduskar@gmail.com or shivalee.duduskar@nih.gov. I look forward to connecting with colleagues who share a similar passion for advancing scientific understanding and improving human health.
National Cancer Institute (Nci)
View- Website:
- cancer.gov
- Employees:
- 4070
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Postdoctoral ResearcherNational Cancer Institute (Nci) Mar 2022 - PresentFrederick, Maryland, United StatesWorking with gene therapy cancer patients to unravel the integration of retroviral vectors
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Founder And Academic Content Creator, Path2Phd AcademiePath2Phd Academie Jan 2021 - PresentCoaching program for aspiring researcher to land into their dream Ph.D. -
Postdoctoral ResearcherAarhus University Dec 2020 - Feb 2022Aarhus, Middle Jutland, Denmarkβ’ Scrutinized the role of P62 in the early stages of STING activation for the interferon release.β’ Investigated the role of P62 in STING activation with respect to HSV viruses and STING activators.β’ Analyzed the interaction of activated STING with P62 on ER membrane.β’ Tested various P62 peptides which plays an inhibitory role in the STING activation. -
Founding MemberThe Founders Vault Jun 2020 - Jun 2021 -
Phd StudentUniversity Of Jena Dec 2015 - Dec 2020Jena Area, Germanyβ’ Optimized and isolated the novel membrane vesicles (MLBs, MVs) secreted by Gram-positive bacteria (GBS and S. aureus).β’ Characterized the novel membrane vesicles by Raman spectroscopy, mass spectroscopy electron microscopy and Cryo-electron microscopy.β’ Designed, edited, and maintained CRISPR-Cas9 knockouts of caspases (CASP4, CASP5, CASP1, ASC) in human macrophages (THP1).β’ Investigated the canonical and non-canonical inflammasome signaling pathways activated by the extracellular vesicles of Gram-positive bacteria for the release of cytokines and alarmins.β’ Investigated the role of STING in the release of IL-1Ξ² upon stimulation of MLBs from Gram-positive bacteria.β’ Analyzed the immunostimulatory RNA packed in the membrane vesicles through Nanopore RNA sequencing and Illumina sequencing.β’ Studied the role of regulatory small RNA of S. aureus in activation inflammasome for the release of cytokines. -
Junior Research FellowAdvanced Center For Treatment Research And Education In Cancer Sep 2014 - Aug 2015Mumbai, Maharashtra, Indiaβ’ HIV 1 protease cloned in PET 11 vector.β’ Transformed into BL21 competent cells and purified proteins from inclusion bodies.β’ Crystal trials was established with different concentration of precipitin.β’ X-ray diffraction and data collection of crystal was obtained.
π Dr. Shivalee D Skills
π Dr. Shivalee D Education Details
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Biotechnology
Frequently Asked Questions about π Dr. Shivalee D
What company does π Dr. Shivalee D work for?
π Dr. Shivalee D works for National Cancer Institute (Nci)
What is π Dr. Shivalee D's role at the current company?
π Dr. Shivalee D's current role is Path2PhD academie mentor π l immunologists π¬I Gene Therapy π§¬l Scientific writer and editor βοΈ.
What schools did π Dr. Shivalee D attend?
π Dr. Shivalee D attended Shivaji University.
What skills is π Dr. Shivalee D known for?
π Dr. Shivalee D has skills like Research, Molecular Biology, Cell Culture, Life Sciences, Polymerase Chain Reaction, Biochemistry, Microbiology, Protein Purification, Scientific Writing, Science Illustration.
Who are π Dr. Shivalee D's colleagues?
π Dr. Shivalee D's colleagues are Isabel Quintanilla Leo, M.sc, Ph.d, Michael Marino, Zhijie Li, Michael Emanuel, Sam (Nih/nci) Roach, P. Boon Chock, John Chittum.
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