Shreya Thammana Email & Phone Number

Manchester, New Hampshire, United States

Clemson, South Carolina, United States

Chronic wounds such as diabetic foot ulcers can pose physical and financial burdens onpatients. Doctors need quick, accurate, and objective methods to diagnose and monitor wound healing. In this study, we investigate the use of biosensors to detect cytokines commonly found in the wound bed, based on impedance measurements.In my departmental honors research project, titled "Fabrication and Characterization of a Nanofiber Composite Biosensor for Chronic Wound Inflammation Diagnosis", I assisted a Ph.D. student with their research and worked on the development and manufacturing of solution blow spun nanofibers as electrical and cell biosensing interfaces.I manufactured and functionalized biosensors through processes such as solution blow spinning, screen printing, and ELISA techniques. Electrochemical impedance spectroscopy and UV-Vis Spectroscopy were used to analyze functionality of the sensors and characterize antibody binding occurring at the electrode surface.I presented my research at the Society of Biomaterials Research Exposition in the spring of 2021. I also completed and presented my departmental honors thesis to the honors board to receive my departmental honors distinction.

Clemson, South Carolina, United States

As a teaching assistant for several core engineering classes (Engineering Disciplines and Skills, Programming and Problem Solving, and Engineering Graphics and Machine Design), I assisted professors by answering students' questions during class, provided weekly tutoring services to students, and graded homework, ensuring that students got the support and assistance to understand complex engineering concepts.

Clemson, South Carolina, United States

A buildup of plaque in the arteries can cause a potentially fatal disease called carotid stenosis, the narrowing of a major blood vessel that leads to the brain. The objective of this project was to create a model of the carotid bifurcation at the stenosis, simulate the patient’s blood flow, and analyze the results to determine whether the patient’s condition is severe enough to cause a stroke. By using CT scans from five patients and SimVascular software, segments of the carotid artery were created and lofted together to create an accurate representation of the shape and path of the carotid artery. To create a simulation, CT scans were opened in SimVascular, where the vessel was traced to make a model and create a mesh. Flow rate data was extracted from patient doppler ultrasound graphs, and then data files were created with time and calculated volumetric flow rate data over one heartbeat. The data was used to run simulations mimicking the human cardiovascular system by applying realistic pressures and flow boundary conditions to the 3D model. The results gained from these experiments provide detailed hemodynamic information that can help inform clinical diagnostics and treatment planning. Research findings were presented with team at the EUREKA! poster forum to Clemson professors and students.

Clemson, South Carolina, United States

Planned and helped execute all the activities and seminars held during this 5-week research program with fellow counselors, helping 33 honors freshmen get a head start on undergraduate research, explore campus, and create valuable peer and faculty connections prior to their freshman year.

Assisted with bioink formulation mixing (over 250 liters) and scale-up efforts on the Process Feasibility Team. Created a comprehensive raw material inventory and conducted quality testing for over 150 lots of material. Utilized an Electronic Laboratory Notebook (Benchling) to collect, visualize, and automate data analysis using SQL.

Greenville, South Carolina, United States

Shadowed prosthetists/orthotists and technicians at the clinic. Observed clinician-patient interactions and patient care at appointments. Learned about prosthetic/orthotic devices and manufacturing, and emerging technologies in the field.

Learned about tire composite materials and rubber technology. Conducted studies focusing on the incorporation of Biochar into rubber, a carbon-negative reinforcing filler used to improve tire life and performance, obtained from sources such as chicken feather meal and corn husks. Made rubber mixes testing various Biochar fillers and conducted materials testing on the samples (rheometer testing, tensile testing, dynamic materials testing, crosslink analysis). Analyzed data and shared findings with the materials research team and vendor to improve the use of Biochar in tire rubber.

Clemson, South Carolina, United States

Cellulose nanocrystals (CNCs) have recently gained attention because cellulose is an abundant, cheap, and biologically degradable material with low cytotoxicity. CNCs are studied as nanocomposites and thin films. They can be synthesized using cellulose from plants, animals, bacteria, and agricultural biomass. The synthesis is done aqueously and with few chemical hazards, making it sustainable. This study investigated the aqueous (liquid phase) behavior of sulfonated CNCs. As a researcher in the lab, I assisted a PhD student by synthesizing cellulose nanocrystals and investigating their liquid phase properties. I learned valuable lab and research skills during this experience and presented my research findings to professors at the annual EUREKA! poster forum.

Bachelor'S Degree, Bioengineering (Biomedical Engineering)

Activities and Societies: President, Tau Beta Pi SC Alpha Chapter (2022-2023). Clemson Bioengineering Diversity & Inclusion Council Member.

High School Diploma, Grade 12

High School Diploma, Grade 10 And 11

High School Diploma, Grade 9