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In cancer patients, the migration of cancer cells away from the primary tumor and their subsequent metastasis to distant organs is the leading cause of mortality. My research interests are focus on the remodeling of the cytoskeleton during the process of cell migration. Aberrant regulation of cell migration drives progression of many diseases, including cancer invasion and metastasis. In particular, my research is focus on the remodeling of extracellular matrix (ECM) that allows cancer cells to alter their microenvironment to clear space and create tracks along which cells can migrate more efficiently. To do that cells form actin-based subcellular structures termed invadopodia or podosomes that are well-characterized as a specialized machinery for ECM degradation. Therefore, the fundamental mechanisms of cell migration and invasion are critical for our understanding of both basic biology and the pathology of disease.
The University Of Toledo
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Research Associate Professor, Department Of Biological SciencesThe University Of ToledoToledo, Oh, Us -
Research Associate Professor, Department Of Biological SciencesThe University Of Toledo Jan 2019 - PresentToledo, Oh -
Research Assistant Professor, Department Of Biological SciencesUniversity Of Toledo Aug 2012 - Jan 2019Toledo, Oh -
Diversity And Inclusion OfficerCollege Of Natural Sciences And Mathematics At The University Of Toledo Jan 2019 - PresentToledo, OhAs an Diversity and Inclusion Officer I work in collaboration with the Vice President for Diversity and inclusion to develop and launch College/Department as well as The University of Toledo's Strategic Diversity Plan.My responsibilities include:- Implement and monitor the College/Department Diversity Plan throughout the year.- In conjunction with departmental curriculum committees and with assistance from the Office of Diversity and Inclusion, create discipline specific teaching modules that highlight the diversity, in particular the presence and contributions of women and ethic minorities in each discipline within the college/unit.- Provide quarterly updates on diversity and inclusion efforts of the college/unit.- Attend quarterly Council of Inclusion Officer meetings.- Chair or co-chair one of the Inclusion Committees. -
Research Assistant ProfessorUniversity Of North Carolina At Chapel Hill 2010 - Aug 2012Chapel Hill, NcMaintain an independent research program aimed at the discovery of molecular mechanisms that regulate cell invasion during pancreatic and breast cancer metastasis. As a secondary project, I worked in vascular smooth muscle differentiation and development. -
Research InstructorUniversity Of North Carolina At Chapel Hill 2004 - 2010Maintain an independent research program aimed at the discovery of molecular mechanisms that regulate cell invasion during breast cancer metastasis. As a secondary project, I worked in vascular smooth muscle differentiation and development. -
Post Doctoral FellowUniversity Of North Carolina At Chapel Hill 2002 - 2004Chapel Hill -
Post Doctoral FellowUniversity Of Alabama At Birmingham 1997 - 2002Birmingham, AlI focused on the process of cell adhesion to extracellular matrix and its role in cell migration. I specifically studied cell-matrix interaction and focal adhesion disassembly.
Silvia Goicoechea Skills
Silvia Goicoechea Education Details
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Universidad Nacional De Mar Del Plata, ArgentinaBiology -
Universidad Nacional De Mar Del Plata, ArgentinaBiology
Frequently Asked Questions about Silvia Goicoechea
What company does Silvia Goicoechea work for?
Silvia Goicoechea works for The University Of Toledo
What is Silvia Goicoechea's role at the current company?
Silvia Goicoechea's current role is Research Associate Professor, Department of Biological Sciences.
What is Silvia Goicoechea's email address?
Silvia Goicoechea's email address is sg****@****unc.edu
What is Silvia Goicoechea's direct phone number?
Silvia Goicoechea's direct phone number is +141953*****
What schools did Silvia Goicoechea attend?
Silvia Goicoechea attended Universidad Nacional De Mar Del Plata, Argentina, Universidad Nacional De Mar Del Plata, Argentina.
What skills is Silvia Goicoechea known for?
Silvia Goicoechea has skills like Molecular Biology, Biochemistry, Science, Confocal Microscopy, Protein Expression, Molecular Cloning, Pcr, Western Blotting, Polymerase Chain Reaction, Life Sciences, Cell Culture, Cell Biology.
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Silvia Goicoechea
Argentina -
SILVIA GOICOECHEA
Operador Socio Terapéutico En Drogadicciones En Centro Psicosocial Argentino, Capital Federal - ArgentinaArgentina -
Silvia Goicoechea
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