Lead Pharma Holding BV. (LPH) is a small, young and dynamic pharmaceutical company located in Den Bosch and Nijmegen, the Netherlands. LPH is is dedicated to develop new medicine against ageing related diseases, especially chronic heart failure and cancer.LPH has developed an innovative strategy that is based on 15 years extensive scientific research in chronic heart failure and other age related diseases and has resulted in the discovery of unique disease mechanisms and methods to discover new medications. LPH uses the following techniques to identify new chemical structures against their targets:• 3-dimensional computer models of the protein of interest and homology modeling • X-ray crystallography• 2-D NMR • Structural protein chemistry • Proteomics – mass spectrometry• Protein production and peptide synthesis• Adult organ specific Stem cell technology used for Human cellular disease and ADME Tox models.LPH's approach will result in new classes of curative drugs for chronic heart failure,cancer and other age related diseases.