Platform CURIECORETECHCustom Single-Cell Omics (CSCO) core facility

in the Systems Neuroscience Lab, under the supervision of Dr. Özgün Gökce- Established a low-volume Smart-seq2 pipeline- Semi-automatised the pipeline with liquid handling robotics- Established a bioinformatics scRNA-seq analysis pipeline- Specialised in aging and neurodegeneration- Characterised the white-matter associated microglia (WAM) in aging- WAM paper made the cover of Neuron and is highly cited since 2021 - Collaborated extensively as main taskforce in the core facility- Main contact for 15 collaborative projects, support in 5 projects- Teaching and supervision responsibilities- Responsible for new users of Sony cell sorter and Formulatrix Mantis- Regular presentation of results within or outside the lab- 6 publications, 2 pre-publications, and 1 book chapter

Intern at the RIKEN – CLST – DGT - Genomics Miniaturization Technology Unit – Yokohama, Japan – under the supervision of Charles Plessy, PhD, unit leader."Vizection: an interactive application for the analysis of big datasets from single-cell transcriptomics studies":- Familiarisation with single-cell related technologies- Design of a statistical analysis pipeline (classification, dimension reduction, etc.)- Development of an R/Shiny application for single-cell data analysis- Encapsulation in an R package available on Github at shamansim/Vizection

Intern at INSA-Lyon – Laboratory MAP – UMR5240 – Villeurbanne, France – under the supervision of Sam Meyer, PhD, docent"Analysis of thermodynamic properties of bacterial promoter sequences and modelling of DNA topology role in transcriptional regulation genome-wide":- Development of Python/R scripts to extract the transcription start sites of genes sensitive to DNA supercoiling- Statistical analyses of the promoter region of DNA supercoiling sensitive genes

"Research for proof of concept of in silico in the last 20 years scientific publications":- Design of a research protocol- Use of bibliographic tools- Familiarisation with a start-up environment