Simone Bonaccorsi, Phd Email & Phone Number

Italy

Switzerland

Gothenburg, Vastra Gotaland County, Sweden

• Combined cell biology, robotic imaging, and Artificial Intelligence analysis to enhance the understanding of nanoparticle delivery and efficacy and study spatio-temporal cell response.• Developed and implemented AI models, used foundation models, to accurately predict and classify cellular responses to nanomedicine, achieving high prediction accuracy.• Conducted in-depth phenotypic analysis on single cells, identifying key factors influencing cargo delivery efficiency and cellular response to nanomedicine.• Improved model robustness by systematically testing under various experimental conditions, increasing overall model reliability by 20%.

Sydney, Australia

- Researched the internalization of nanoparticles into the nucleus of breast cancer cell lines and drug delivery, including coordinating and performing laboratory experiments. - Conducted in-depth statistical, qualitative, and quantitative analysis of confocal microscopy data using Matlab and 3D renderer software. - Fostered a collaborative working relationship with the Riken Institute in Japan to design and microfabricate microfluidic devices for single cell studies on glass substrate. - Spearheaded the successful development of a data analysis tool for 3D analysis of experimental data. - Co-authored two scientific publications in peer-reviewed journals; contributed to scientific publications by performing COMSOL simulations for nanoparticles-based biosensors.

Tokyo, Japan

- Headed the development of a prototype of microfluidic devices for single cell studies. - Ensured optimal quality while conducting bioinformatic analysis of sequenced data. - Aligned objectives and bridged communications with cross-functional teams. - Documented and maintained detailed records of study findings and results. - Identified and resolved issues and discrepancies in a timely manner to mitigate risks. - Adhered to all internal and external regulations, standards, protocols, and best practices.

Boston, Massachusetts, United States

- Established new processes for fabrication of tumor-on-chip devices and led the microfabrication of 3D vascularized and perfusable microfluidic devices for tumor-on-chip devices. - Tasked with conducting statistical, qualitative, and quantitative analysis of experimental data collected through confocal microscopy. - Provided high-quality support and leadership to five undergraduate and graduate students participating in research projects and writing theses.

Lausanne, Vaud, Switzerland

- Maintained responsibility for creating and testing reversible peptide MHC technology. - Liaised with team members to analyze new product development procedures and techniques. - Optimized product performance and process efficiency while minimizing costs by improving existing formulation and processes.

Lausanne Area, Switzerland

- Utilized flow cytometry and fluorescence microscopy for cancer therapy, with a focus on Adoptive Cell Transfer Therapy, to conduct experiment, data acquisition, and data analysis of peptide MHC-T-cell receptor association/dissociation kinetics. - Enabled high throughput screening by designing microfluidic devices prototypes for single cell analysis. - Coordinated with the École Polytechnique Fédérale de Lausanne (EPFL) research team in Switzerland.

Cameroon

- Reviewed and analyzed radiology department conditions, work standards, and safety procedures in Cameroon hospitals. - Facilitated meetings with government and hospital stakeholders to communicate radioprotection regulations and standards. - Trained and educated technicians on radioprotection through meetings and discussions. - Tested and analyzed on-site safety equipment performance and operations. - Drafted and prepared technical reports outlining processes and improvements.

London, United Kingdom

- Charted the development of a noninvasive ultrasonic pulse sequences system with interconnected transducers and electronic components for the purpose of drug delivery and BBB penetration. - Orchestrated and managed the implementation of an automated data acquisition system. - Succeeded in co-authoring two scientific publications resulting from the new system.

Turin Area, Italy

R&D

Doctor Of Philosophy - Phd, Chemistry, Faculty Of Science

Master'S Degree, Nanotechnology

Master'S Degree, Nanotechnology

Master'S Degree, Nanotechnology

Bachelor'S Degree, Electrical And Electronics Engineering