- Define product features- Define product marketing strategy and lead marketing team to conduct market analysis- Identify and seize business opportunities and manage business relationships with collaborators and customers- Lead R&D team to develop ultra-fast bio-detection products

- Principal Investigator of a H2020 Marie Curie Individual Fellowship project (EUR 185,076 in 2 years, 10-15% successful rate) aims at developing a low-cost and reliable microfluidicdisposable chip based on qPCR technology and producing the corresponding plug-and-play operating system for fast point-of-care diagnosis of infectious disease- Responsible for IP filling, FTO analysis- Submitted 17 grant proposals- Market expanding in Asia

Joint research team: Dr. Zhiping Wang @SIMTech, Agency for Science, Technology and Research (A*STAR), Prof. Stephen. T. Wong @TMHRI, Houston Methodist Research Institute l and Prof. Chang, Joseph Sylvester@ Nanyang Technological UniversitityLead the team successfully built a self-contained, portable and automated molecular diagnostic MiniLab for rapid liver toxicity testing- Integrated mRNA extraction from liver tissue and RT-PCR test in one microfluidic chip- Automatized and miniaturized a point-of-care testing device to run the entire procedure- Analyzed and reported multiple biomarkers from liver tissue directly within 1 hour

1. Investigated combined effects of multi-topographical and surface chemical cues on mesenchymal stem cell fates- Fabricated PDMS hybrid patterns of microholes, micropillars and microgrooves - Verified that hybrid PDMS micropatterns would enhance MSCs adhesion, proliferation and osteogenic differentiation2. Controlled neural network in a microfluidic cell-trapping system - Designed a microfluidic chip to trap single neural cell - Investigated how the geometry of micropatterns influence and control neural network

Co-supervisor of PhD students and research interns1. Integrated microfilter into microfluidic device for capture of circulating tumor cells (CTCs)- Integrated the microfluidic chip with a microfilter with conical-shaped holes- Captured CTCs in cancer patient blood at high efficiency by size-dependent filtration2. Fabricated PDMS microlattices as a novel three-dimensional neuron cell culture platform - Produced 3D lattice-type scaffold from a photolithography defined 2D template- Observed a higher neuron to astrocyte ratio and a higher degree of cell ramification in 3D lattice

Supervisor: Prof. Yong Chen1. Captured rare cells in human blood samples in a microfluidic device- Integrated flow-derivation microstructures into microfluidic channels- Trapped endothelial progenitor cells (EPCs) in human blood efficiently by the narrowly spaced two linear arrays of microcolumns2. Integrated ZnO nanowires into microfluidic device to improve photocatalytic efficiency- Grew ultra-long and well-aligned ZnO NWs in microfluidic chamber- Highly improved the photodegradation efficiency of methylene blue3. Gel-embossed gelatin nanopatterns for cell culture studies- Demonstrated a novel technique to generate defined nanoscale patterns with gelatin- Verified the compatibility of nanopatterned substrate for cell adhesion and proliferation4. Anisotropic wet etched silicon substrates for reoriented and selective growth of ZnO nanowires- Discovered higher growth rate of ZnO nanowires on Si <111> facets than on <100> facets- Investigated enhanced wetting property of micro- and nano- dual scale patterned surface

Electrospun PLGA aligned nanofibers for human cardiac tissue engineering

Integrated surface plasmon resonance (SPR) microscope into microfluidic device