Scott Miller Email & Phone Number

San Francisco, Ca

• Led sensor development program for personal health monitoring system for continuous, high resolution measurement of metabolites and electrolytes.• Developed productizable wearable biosensors on MEMS-based transdermal form factor. Multiple patent applications in progress.• Conceptualized and developed multiple-analyte sensing schemes for in vivo biosensors.• Demonstrated in vivo continuous metabolite monitoring with prototype sensor patch.• Managed R&D team of scientists and engineers.• Met all R&D goals and timelines.• Streamlined laboratory systems and operation to increase experiment throughput ten-fold.

• Co-investigator and co-author on successful NIH, NSF, and DOD SBIR grant and contract applications securing $3M+ in R&D funding for bio-analytical lab-on-a-chip systems.• Technical lead for medical device development projects. Responsible for conceptualization, development, and validation of innovative medical diagnostic and research tools. Select Examples:• Multiplexed Biosensor for Detecting Low Abundance Cancer. An optical microfluidic cancer marker assay system was developed for point-of-care diagnostics. Project successfully resulted in NIH SBIR Phase II funding.• Hand-held Device for Multiplex Analysis of Proteins in Blood. A 12-sensor immunoassay microchip was developed and demonstrated. Successfully resulted in DOD Phase II funding.• Label Free Nucleic Acid Assays for POC Diagnostics. An electrochemical impedance spectroscopy biosensor with high sensitivity for DNA/RNA was developed. Project successfully resulted in NSF SBIR Phase II funding.• MEMS Based Continuous Alcohol Monitoring Device. A system was developed for transdermal ISF extraction into a microfluidic patch with enzymatic 3D-micro-electrode.• Managed project workflows to meet project goals and timelines.• Directed, mentored, trained, and advised junior scientists and interns.

• Research and development of nanofluidic and microfluidic systems for pre-concentration and electrophoretic separation of proteins as proteomics research tools. • Investigated nature of electroosmotic flow and electrophoresis at nanofluidic-microfluidic interfaces.• Discovered and characterized ionic current rectification across asymmetric nanofluidic-microfluidic interface.• Developed nanocapillary membrane-based electrokinetic protein concentrator on a microfluidic platform.• Developed capillary, microchannel, and membrane coating technologies for control of surface chemistry, electroosmotic flow, and biocompatibility for capillary electrophoresis and lab-on-a-chip platforms.

• Researched novel applications for carbon nanotube membranes and electrodes including fuel cells, battery electrodes, electrochemical sensors and actuators, and nanofluidic molecular gates.• Fabricated template-synthesized nanomaterials using CVD, electroless plating, and other thin-film deposition methods.• Characterized carbon nanomaterials using SEM, TEM, electrokinetic analysis, permeability analysis, XPS, and EDS.• Modulated molecular delivery across nanotube membranes using electroosmotic flow.• Modified carbon, gold, and silica nanotube membrane surface chemistries with various coating methods: thiols, sol-gels, silanes, surfactant, organic derivatives, nanoparticles, and electro-active polymers.• Published the first reports of electrokinetic fluid transport across carbon nanotube membranes and dynamic modulation of electroosmotic flow by electrochemical control of redox surface chemistries.• Graduate research advisor: Prof. Charles R. Martin

Doctor Of Philosophy (Phd), Analytical Chemistry - Electrochemistry

Bachelor Of Science (Bs), Chemistry